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46 results on '"drug discovery3003 pharmaceutical science"'

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1. Antimicrobial treatment with the fixed-dose antibiotic combination RHB-104 for Mycobacterium avium subspecies paratuberculosis in Crohn’s disease: pharmacological and clinical implications

2. Vaccination of healthcare workers: is mandatory vaccination needed?

3. Risankizumab for the treatment of moderate to severe psoriasis

4. The carbonic anhydrase IX inhibitor SLC-0111 sensitises cancer cells to conventional chemotherapy

5. Trace amine-associated receptor 1: a multimodal therapeutic target for neuropsychiatric diseases

6. Thymosin β4 limits inflammation through autophagy

7. A patent review of butyrylcholinesterase inhibitors and reactivators 2010–2017

8. Atezolizumab for the treatment of breast cancer

9. Farnesoid X receptor modulators 2014-present: a patent review

10. Opportunities and challenges in drug discovery targeting metabotropic glutamate receptor 4

11. Reprogramming T-cells for adoptive immunotherapy of ovarian cancer

12. Ipilimumab for the treatment of metastatic prostate cancer

13. Severe eosinophilic asthma: from the pathogenic role of interleukin-5 to the therapeutic action of mepolizumab

14. Spotlight on ertugliflozin and its potential in the treatment of type 2 diabetes: evidence to date

15. Targeting endothelin-1 receptor/β-arrestin1 network for the treatment of ovarian cancer

16. Ambulatory blood pressure parameters after canrenone addition to existing treatment regimens with maximum tolerated dose of angiotensin-converting enzyme inhibitors/angiotensin II type 1 receptor blockers plus hydrochlorothiazide in uncontrolled hypertensive patients

17. TRAP1: a viable therapeutic target for future cancer treatments?

18. Recent progress on curcumin-based therapeutics: a patent review (2012-2016). Part II: curcumin derivatives in cancer and neurodegeneration

19. Are tumor-infiltrating lymphocytes protagonists or background actors in patient selection for cancer immunotherapy?

20. Nutrient sensing pathways as therapeutic targets for healthy ageing

21. Pertuzumab and breast cancer: another piece in the anti-HER2 puzzle

22. Hyperbaric oxygen therapy modulates serum OPG/RANKL in femoral head necrosis patients

23. The role of 5-arylalkylamino- and 5-piperazino- moieties on the 7-aminopyrazolo[4,3-d]pyrimidine core in affecting adenosine A1 and A2A receptor affinity and selectivity profiles

24. Systemic alkalinisation delays prostate cancer cell progression in TRAMP mice

25. Allosteric inhibition of carnosinase (CN1) by inducing a conformational shift

26. Spotlight on the 9-valent HPV vaccine

27. Spotlight on frovatriptan: a review of its efficacy in the treatment of migraine

28. Nanopatterned acellular valve conduits drive the commitment of blood-derived multipotent cells

29. Ecotoxicity interspecies QAAR models from Daphnia toxicity of pharmaceuticals and personal care products

30. Green synthesis of silver nanoparticles using Pimpinella anisum seeds: antimicrobial activity and cytotoxicity on human neonatal skin stromal cells and colon cancer cells

31. The evolving role of monoclonal antibodies in the treatment of patients with advanced renal cell carcinoma: a systematic review

32. Pembrolizumab: the value of PDL1 biomarker in head and neck cancer

33. Novel therapeutic options for cachexia and sarcopenia

34. FightingNeisseria meningitidis: past and current vaccination strategies

35. Synthesis and structural analysis of halogen substituted fibril formation inhibitors of Human Transthyretin (TTR)

36. Chemical composition and biological activities ofEruca vesicariasubsp. longirostrisessential oils

37. Inhibition of carbonic anhydrase isoforms I, II, IX and XII with secondary sulfonamides incorporating benzothiazole scaffolds

38. The protective effect of Hypericum connatum on stress-induced escape deficit in rat is related to its flavonoid content

39. Modelling the aquatic toxicity of ionic liquids by means of VolSurfin silicodescriptors

40. Could autologous hematopoietic stem cell transplantation be considered a second-line treatment option in relapsing-remitting multiple sclerosis? A critical editorial

41. X-ray crystal structure and activity of fluorenyl-based compounds as transthyretin fibrillogenesis inhibitors

42. Dopamine heteroreceptor complexes as therapeutic targets in Parkinson’s disease

43. Updates and achievements in virology

44. A Kinetic Study on the Interaction Between Tazobactam (A Penicillanic Acid Sulphone Derivative) and Active-Site Serine B-Lactamases

45. Selective use of vandetanib in the treatment of thyroid cancer

46. Labeling and exocytosis of secretory compartments in RBL mastocytes by polystyrene and mesoporous silica nanoparticles

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