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1. GP2017, an adalimumab biosimilar: pharmacokinetic similarity to its reference medicine and pharmacokinetics comparison of different administration methods

Author

Oliver von Richter, Thomas Koernicke, Lena Lemke, Johann Poetzl, Julia Jauch-Lembach, Maria Velinova, Ellen Schuck, Halimuniyazi Haliduola, Andrej Skerjanec, and Rainard Fuhr

Subjects
Adult, Male, musculoskeletal diseases, 0301 basic medicine, Adolescent, Clinical Biochemistry, Pharmacology, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Double-Blind Method, Pharmacokinetics, Similarity (network science), Drug Discovery, Healthy volunteers, Adalimumab, Humans, Medicine, skin and connective tissue diseases, Biosimilar Pharmaceuticals, business.industry, Drug Administration Routes, Biosimilar, Middle Aged, Healthy Volunteers, humanities, 030104 developmental biology, Therapeutic Equivalency, 030220 oncology & carcinogenesis, business, medicine.drug
Abstract

Background: To compare the pharmacokinetics of Sandoz biosimilar adalimumab (GP2017) with reference adalimumab (Humira) in healthy volunteers (PK similarity study) and to compare the pharmacokineti...

Published
2019

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