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Investigation of the chemical constituents of Salvia judaica growing wild in Jordan led to the isolation and identification of 15 known compounds. These included: luteolin-3'-methyl ether (1), indole-3-carboxyaldehyde (2), p-hydroxybenzaldehyde (3), tricin (4), apigenin (5), methyl isoferuloyl-7-(3,4-dihydroxyphenyl) lactate (6), methyl rosmarinate (7), rosmarinic acid (8), salvigenin (9), β-sitosterol (10), 3β, 28-dihydroxyurs-12-ene (11), cirsilineol (12), 2,3-dihydroxyurs-12-en-28-oic acid (13), β-sitosteryl glucoside (14), and tormentic acid (15). Compounds 6 and 7 exhibited strong radical scavenging and chelating activities as compared to α-tocopherol and ascorbic acid, compound 7 showed a 2-fold greater antioxidant activity as compared to compound 6. Furthermore, low doses of compounds 6 and 7 were able to inhibit the growth of leukemic (HL-60, Jurkat, K562 and CCRF-SB) and solid tumor cells (MCF-7, MDA-MB-231 and Caco-2). Compound 7 showed a ca. 3-4-fold stronger cytotoxicity against the tested cells as compared to compound 6.

In this study, the composition of the essential oil, flavonoid and phenolic contents, and the antioxidant activities of three Phlomis species from Jordan (P. viscosa Poiret., P. platystegia Post. a...

The antioxidant activity of the essential oils obtained from Ononis Natrix L. and Ononis Sicula Guss were investigated by the DPPH and ATBS methods. The oils exhibited good to moderate antioxidant activity in a concentration-dependent manner. Essential oils of the two plants were analyzed by GC and GC- MS. Seventy-seven components (95.60 %) were characterized in the essential oil of O. Sicula. The oil was rich in oxygenated sesquiterpenes (66.29 %), sesquiterpene hydrocarbons (20.10 %) including selin-11-en-4-α-ol (12.76 %) and α-selinene (6.27 %) as the major constituents. From the 85 identified compounds (97.11 %) in the oil of O. Natrix (2E,6E)-farnesol (18.83 %), dodecanal (12.58 %) and 2-phenyl ethyl tiglate (5.20 %) were the main constituents.

The objective of this study was to identify risk factors for back pain among health care workers of Saudi Aramco. A validated questionnaire was used to collect information on back pain in the last 12 months as well as relevant risk factors among health care workers at a single Saudi Aramco health care facility. Completed responses were received from 964 of 3,295 workers. Three significant predictors for the presence of back pain were identified: female gender (odds ratio [OR] = 1.9, 95% confidence interval [CI] = 1.3-2.7), Saudi nationality (OR = 2.3, 95% CI = 1.4-3.9), and working as a surgeon (OR = 5.4, 95% CI = 1.4-21.5). Educational level was of borderline significance (OR = 1.6, 95% CI = 0.98-2.7). An interaction between gender and race was identified, with Saudi females being at particularly high risk of reporting back pain (OR = 3.9, 95% CI = 1.8-8.5). Gender, occupation, and nationality were identified as risk factors for back pain, and a particularly high risk was seen among female Saudis health care workers in Saudi Aramco. Nationality may be important because of cultural difference between groups, but also because of differences in benefits available.

The new substituted cyclopentadienyl organoiron dimers [Fe- (ButC5H4)(CO)2]2, I and [Fe(1,3-di-ButC5H3)(CO)2]2, II, were prepared from the reaction of Fe2(CO)9 with t-butylcyclopentadiene, or 1,3-di-t-butylcyclopentadiene. The equilibrium concentration of the trans-geometrical isomer decreases in the order II>I> [FeCp(CO)2]2 as a result of increasing bulkiness of Cp-substituents and increasing the steric repulsion in the cis-configurations. The 1H NMR spectra of I and II showed an anisotropic shielding effect of the bridging metal-carbonyl on the cyclopentadienyl protons.