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Introduction: Timely detection of Mycobacterium tuberculosis (Mtb) remain critical in the effective management of patients with suspected tuberculosis (TB) disease. While recommendations for determination of latent TB or TB exposure in industrialized countries support the use of interferon-gamma release assays (IGRA), including the QuantiFERON Gold In-Tube (QFT-GIT) and T-SPOT.TB tests, disagreement exists within neuro-ophthalmologic practice on screening protocols for TB which affects ocular function.Areas covered: The authors have reviewed the current literature discussing the manifestation of tuberculosis in neuro-ophthalmic disease. Our literature search expands on current recommendations for TB screening in neuro-ophthalmology, including a comparison of the currently available tests for screening: the TST, QFT-GIT, and T-SPOT.TB tests. We review the literature on regional TB prevalence as it applies to clinical decision making for screening, as well as medical and social factors which may cre...

Recently, the United States Food and Drug Administration approved vigabatrin (Sabril®) for the treatment of adults with refractory complex partial seizures and infants with infantile spasms. Howeve...

The aim of this article is to review disorders affecting the optic chiasm and develop a logical clinical approach to the diagnosis of a chiasmal syndrome. A review of recent and relevant literature was performed to highlight chiasmal syndromes and pathology, as well as to discuss current methods of diagnosis, prognosis and considerations in the treatment of a patient presenting with a chiasmal disorder.