1. The prognostic value of the lactate/albumin ratio for predicting mortality in septic patients presenting to the emergency department: a prospective study
- Author
-
Maha Makki, Karim Abdeldaem, Mohamed Khamis, Hani Tamim, Gilbert Abou Dagher, Mohamad Assaf, Ralphe Bou Chebl, Mirabelle Geha, Saadeddine Haidar, Nadim Kattouf, and Nour Halawi
- Subjects
Adult ,medicine.medical_specialty ,Malignancy ,Gastroenterology ,sepsis ,Sepsis ,Albumins ,Internal medicine ,lactate/albumin ,medicine ,Humans ,Lactic Acid ,Prospective Studies ,Prospective cohort study ,albumin ,Outcome ,Retrospective Studies ,lactate ,Septic shock ,business.industry ,Significant difference ,Albumin ,General Medicine ,Emergency department ,Prognosis ,medicine.disease ,mortality ,Shock, Septic ,infection ,Emergency Medicine ,Biomarker (medicine) ,Emergency Service, Hospital ,business ,Research Article - Abstract
Objectives Lactate/albumin (L/A) ratio is a biomarker in sepsis that has been shown to outperform lactate. This prospective study aims to validate the superior prognostic value of the L/A ratio to lactate in sepsis and septic shock. Methods Prospective cohort conducted from September 2018 till February 2021 on adult patients presenting to the Emergency Department (ED) at a tertiary care centre with sepsis or septic shock. The primary outcome was the prognostic value of the L/A ratio compared to lactate with regards to mortality. Results A total of 939 septic patients were included throughout the study period. A total of 236 patients developed septic shock. The AUC value of the L/A ratio in septic patients was 0.65 (95% CI 0.61–0.70) and was higher than that of lactate alone 0.60 (95% CI 0.55–0.64) with a p
- Published
- 2021