Search

New mixed-ligand heteronuclear complexes of lanthanum and cobalt (nickel) with acetylacetone (НАА) and α,α'-dipyridyl were synthesized and investigated by physic-chemical methods of analysis (eleme...

Transition metal carboxylates with O- and N-donor ligands are interesting for their structural features. Seven novel isonicotinamide(inic)-based metal complexes of [Cd(inic)2(L1)2(H2O)2] · 2H2O (1)...

A new Cu(II) coordination polymer (CP) of [Cu5(µ3-OH)2(bcpt)4(bib)2] (1, bib = 1,4-bis(1-imidazoly)benzene and H2bcpt = 3,5-bis(3′-carboxyphenyl)-1,2,4-triazole) was synthesized by reaction of Cu(N...

In this current experiment, by applying the mixed-ligand synthesis method, two coordination polymers (CPs) containing Co(II) were created triumphantly with reaction between 1,3-bis(1-imidazoly)benzene (mbib) and Co(II) salts with the aid of diverse carboxylic ligands, and their chemical formulae are [Co3(opda)3(mbib)4(H2O)4]·2H2O (1, H2opda is 1,2-phenylenediacetic acid) and [Co(mpda)(mbib)]·H2O (2, H2mpda is 1,3-phenylenediacetic acid). The two compounds’ magnetic performances suggest that between the adjacent metal ions, there present the antiferromagnetic coupling. The evaluation of their treatment activity against chronic subdural hematoma was carried out and the relevant mechanism was studied simultaneously. Firstly, before the treatment of compound, the chronic subdural hematoma was generated. Furthermore, the enzyme-linked immunosorbent assay detection kit was implemented and in hematoma capsule, the anti-inflammatory cytokines level and pro-inflammatory cytokines level was detected. Additionally, the cytotoxicity of compounds 1 and 2 on the normal human cells was determined with Cell Counting Kit-8 assay. Above all, we proved compound 1 decreased the pro-inflammatory cytokines content and increased the anti-inflammatory cytokines content in the hematoma capsule, which is much stronger than that of compound 2. Both compounds 1 and 2 showed no cytotoxicity on the normal human cells.

By utilizing the mixed-ligand method, two novel metal-organic frameworks (MOFs) based on Zn(II) ions as nodes with the chemical formulae of {[Zn2.5(abta)(trz)2(H2O)]·3H2O}n (1, Htrz = 1H-1,2,4-triazole) and [Zn3(abta)2(bibb)2]n (2, bibb = 1,4-bis(benzimidazol-1-yl)-2-butene) were produced via Zn(NO3)2·6H2O reacting with the 1-aminobenzene-3,4,5-tricarboxylic acid (H3abta) in the existence of distinct nitrogen-donor co-ligands. The different N-donor ligands result in their distinct framework structures, and the compound 1 with higher solvent accessible void and large window size shows highly heterogeneous catalytic activities for Knoevenagel condensation. The treatment of Staphylococcus aureus biofilms formation during spine surgery incision infection and the related mechanism was explored at the same time. First of all, the S. aureus bacterial numbers in the infectious site was measured under compound 1 or 2 treatment. In addition to this, the relative expression levels of the genes related with S. aureus biofilms was determined with real time RT-PCR.

Based on 5-dimethylamino-isophthalic acid (H2dia) and 1,2-bis(4-pyridyl)ethylene (bpe) mixed linkers, a new Cu(II) coordination polymer material, [Cu(dia)(bpe)(H2O)]n (1), has been successfully pre...

By a bifunctional organic ligand 2-(benzimidazol-1-yl)terephthalic acid (H2bitp) featuring both imidazol-carboxylate groups, two new Cu(II)-containing coordination polymers (CPs) with the chemical ...

Two new mixed-ligand coordination polymers based on the Ni(II) ion as the metal center [Ni(L1)(DCTP)] n (1, L1 = 1,1′-(1,4-butanediyl)bis-1H-benzimidazole) and [Ni(L2)(DCTP)] n (2, L2 = 1,4-bis(5,6...

Two new mixed-ligand coordination polymers (CPs) with the chemical formulae of [Co(L)(phen)]n (1, phen = 1,10-phenanthroline and [Co(L)(4,4′-bipy)4·2H2O]n (2, 4,4′-bipy = 4,4′-bipyridine) have been...

By applying the mixed-ligand method, a new Co(II)-based coordination polymer with the chemical formula of {[Co2L(4,4′-bipy)0.5(H2O)] · 0.25H2O}n (1) have been successfully prepared by reaction of C...

In the current study, two new transition metal-organic coordination polymers (CPs) with the chemical formula of [Cu(L)(OBA)(H2O)]n (1) and [Co(L)(OBA)]n (2) (H2OBA = 4,4(L)(OBA)]dy, two new traL = ...

Two new mixed-ligand coordination polymers with the chemical formulae of {[Co(L1)(bdc)](H2O)}n (1, L1 = 1,4-bis((1H-benzo[d]imidazol-1-yl)methyl)benzene, H2bdc = terephthalic acid) and {[Co(L2)(bdc...

In the current study, a novel mixed-ligand coordination polymer, {[Co(L)(dpe)]·(ClO4)} (1) (H2LCl = 3-carboxy-1-(3-carboxybenzyl)pyridin-1-ium, dpe = (E)-1,2-di(pyridin-4-yl)ethene), was synthesize...

In the current study, two new Cu(II)-containing coordination polymers (CPs) with the chemical formula of {[Cu2(Py2TTz)(2-CH3-BDC)2]·2(DMF)·3(H2O)}n (1, 2-CH3-H2BDC = 2-methyl-1,4-benzenedicarboxyli...

Two Co(II)-containing coordination polymers, {Co(TDC)(TPB)0.5·H2O}n (1) and {[Co2(2,6-NDC)2(TPB)]·MeCN·3H2O}n (2) (TPB = 1,2,4,5-tetra(4-pyridyl)benzene, H2TDC = 2,5-thiophenedicarboxylic acid, 2,6...

A new 3D Cd(II) coordination polymer, {[Cd2(btc)(HL)(H2O)]·3H2O}n (1) (H2L= 3-(1H-pyrazol-4-yl)-5-(pyridin-2-yl)-1, 2, 4-triazole; H3btc = 1,3,5-benzenetricarboxylic acid), has been synthesized by ...

By using a mixed-ligand approach, two new coordination polymers with the chemical formula of {[Zn(L)(ip)·H2O]8}n (1, H2ip = isophthalic acid and L = 1,1’-(2-methylpropane-1,3-diyl)bis(1H-benzo[d]im...

The reaction of dimethyltin(IV) dichloride (DMT) with homopiperazine (HPIP) was studied. The equilibria of the complexes formed in solution were investigated. The complexes detected are of 1:1 stoi...

Solvothermal reactions of Co(OAc)2·4H2O or Ni(NO3)2·3H2O with 1,4-bis(benzimidazol-1-ylmethyl)-benzene (bmib) ligand and 1,4-terephthalic acid (H2bdc) afforded two 2-dimensional coordination polyme...

By employment of a mixed-ligand strategy, two coordination polymers were synthesized via the hydrothermal approach utilizing two positionally isomeric carboxylic acid ligands 1,4-benzenedicarboxyli...

Two new mixed-ligand coordination polymers with the chemical formulae of {[Zn3(nbta)2(bpfp)2(H2O)2](H2O)2}n (1, H3nbta = 5-nitro-1,2,3-benzenetricarboxylic acid, bpfp = bis(4-pyridylformyl)piperazi...

A systematic investigation into the reactions of Cd(NO3)2·4H2O with o- and p-phenylenediacetic acid within the presence of the semi-rigid 1,4-bis(imidazol-1-ylmethyl)benzene (bimb) co-ligands under...

In this study, two new mixed-ligand coordination polymers (CPs) {[Cd6(nbta)3(bimb)4(H2O)](H2O)3}n (1, bimb = 4,4′-bis((1H-imidazol-1-yl)methyl)−1,1′-biphenyl) and [Co3(bib)2(nbta)2]n (2, bib = 1,4-...

In the current study, two new mixed-ligand coordination polymers with the chemical formulae of {[Co(L1)0.5(oba)·DMF]·DMF·H2O} (1, L1 = N,N′-bis(4-pyridylmethyl)-naphthalene diimide, H2oba = 4,4′-ox...

The Schiff base ligand L is developed from furan-2-carboxaldehyde, 4-aminoantipyrine together with 2-aminothiazole. The mixed ligand complexes are developed from the condensation of above Schiff base ligand L, 1,10-phenanthroline as well as metal(II) acetates of Co(II), Ni(II), Cu(II), and Zn(II). The newly produced compounds were characterized using molar conductance, elemental analysis, XRD, mass, UV-Vis, 1H NMR as well as IR spectral techniques. The X band ESR of [CuLphen] complex was recorded at 300 and 77 K. Geometry and Mulliken charge distribution of the L were studied using Density functional theory (DFT). In vitro biological analysis of L and its [CoLphen], [NiLphen], [CuLphen] as well as [ZnLphen] complexes were studied against bacterial variety such as Pseudomonas aeruginosa, Escherichia coli as well as Staphylococcus aureus. The fungal varieties include Aspergillus niger and Candida albicans. The potent DNA cleavage activities of L as well as its complexes were evaluated.

In this work, by employment of a rod-like ligand 4,4′-bis(imidazol-1-yl)-biphenyl (bibp) as the building block, a new Zn(II)-containing coordination polymer with the chemical formula of {[Zn2(HCO2)...

New mixed ligand complexes of nickel(II) were synthesized by using dibasic H/5-bromo-/5-chloro-/4-hydroxy-2-hydroxybenzophenone-thiosemicarbazones (L1–4H2) and [Ni(PPh3)2Cl2]. The ligands and complexes were characterized by cyclic voltammetry, infrared, 1H and 31P NMR spectroscopy techniques. Crystallographic analyses of the 5-bromo-substituted (2) and 5-chloro-substituted (3) complexes as representatives were performed and so confirmed the ONS chelate structure and presence of PPh3 as co-ligand in the complexes. To reveal the antioxidant properties of the compounds, TEAC values (by CUPRAC method) were determined along with free radical-scavenging activity (by DPPH method). The compounds bearing 4-hydroxy substituent, L4H2 and complex 4 were the most effective compounds. The relationship between structure and antioxidant capacity in the context of benzophenone substituents and nickel(II) center was evaluated. Electrochemical results revealed that all complexes displayed metal-centered and ligand-centered redox processes. The antioxidant capacities of complexes were well correlated to electrochemical parameters.

In this study, we report the synthesis and structural characterization of two new Co(II) and Cu(II) containing coordination polymers {[Co2(btc)(mbtz)2]·7H2O}n (1), [Cu2(btc)(mbtz)2]n (2) by using t...

The solvothermal reaction of Cd(NO3)2·4H2O with different donor ligands afforded two new Cd(II)-based coordination polymers [Cd(Hcia)(btz)]n (1, H3cia = 5-(4-carboxyphenoxy)isophthalic acid, btz = ...

Mixed ligand approach has been successfully applied to design coordination polymers with diversiform architectures. In this study, two novel mixed-ligand Zn(II)-based coordination polymers ...

In this work, a new Ni(II)-based coordination polymer (CP) with the chemical formula of {[(Ni)2(L1)(L2)(H2O)2](DMF)2}n (1, H4L1 = 5-((3,5-dicarboxybenzyl)oxy)isophthalic acid, L2 = 2,4,6-tr...

Alcohol vapour sensors can be used in many fields, such as food quality monitoring, etc. Herein, we developed an alcohol vapour sensor based on the quartz crystal microbalance (QCM) technology. A m...

A series of mixed-ligand Cu(II) complexes of the type: (i) [Cu(l-pro)(diimine)(H2O)n](ClO4) (n = 0 or 1), where l-pro is l-proline and diimine is 2,2′-bipyridine (bpy; 1), (ii) 4,4′-dimethy...

Tris(glycinato)Mn(III) and its mixed ligand complexes with azido-, thiocyanato-, chloro- and bromo- groups have been synthesized and characterized by UV–Vis spectrophotometry, IR spectropho...

Coordination polymers (CPs) of mixed-ligand lanthanide complexes [Ln2(1,3-pdta)(TPA)(H2O)2]n·nH2O [Ln = La, 1; Ce, 2; Pr, 3; Nd, 4] (1,3-H4pdta = 1,3-propanediaminetetraacetic acid; H2TPA = terephthalic acid) were hydrothermally synthesized with flexible 1,3-pdta and rigid TPA ligands. Moreover, lanthanide propanediaminetetraacetates [Ln(1,3-Hpdta)(H2O)]2n·nH2TPA·xH2O [Ln = Sm, 5; Gd, 6] with multi-layered structures were also obtained. In 1–4, both 1,3-pdta and TPA coordinate with lanthanide ions through carboxyl oxygen and nitrogen atoms. In 5 and 6, only 1,3-Hpdta coordinates with the central lanthanide ion, where one nitrogen atom in 1,3-Hpdta is protonated, and TPAs are crystallized as H2TPA with the central multi-layered structures of [Ln(1,3-Hpdta)(H2O)]2n through very strong hydrogen bonds [2.504(4) Å]. Solid-state 13C NMR analysis of 1 revealed the coordination of carboxyl groups. However, the methylene groups of 1,3-pdta showed an obvious upfield shift, which can be attributed to the effects of the phenyl ring in TPA ligand. The successful synthesis of these mixed-ligand lanthanides provides a rational design of such lanthanide CPs with flexible and rigid ligands.

A new 2 D Cu(II)-based coordination polymer (CP) {[Cu5(Hcia)4(dpp)2(H2O)2(μ-OH)2]·2H2O}n (1) was designed and synthesized via using the mixed-ligand strategy, using 1,3-di(4-pyridyl)propane (dpp) colinker with a flexible spacer H3cia (H3cia: 5-(2-carboxybenzyloxy)isophthalic acid). Furthermore, we use the grinding method to downsize the complex 1 to nano-region (denoted as nano 1 hereafter). Furthermore, in order to determine the inhibitory effect of nano 1 on the viability of the BT474 breast cancer cells, the Cell Counting Kit-8 (CCK-8) was performed firstly. Then, the Annexin V-FITC/PI staining method was used to evaluate the BT474 breast cancer cells apoptosis levels after treated with nano 1. Next, the reactive oxygen species (ROS) detection kit was used in this study to determine the ROS level in the cancer cells after nano 1 treatment. By calculating posture scores and docking, the latent binding pattern of compound to receptor DNA were explored.

A new Zn(II) metal-organic framework (MOFs), [Zn(BTC)(HME)]·(DMAc)(H2O) (1, H3BTC =1,3,5-benzenetricarboxylic acid, HME = protonated melamine, DMAc = N,N-dimethylacetamide), has been synthesized un...

Titanium complexes with composition TiCl2(L)(L1) and TiCl2(L)(L2) [where, L = benzoylacetone (bzac) and L1 = 1,2-diaminocyclohexane (dach), 1,10-phenanthroline (phen) L2 = 1-adamantylamine (ada)] h...

Acyclic nucleoside phosphonates (ANPs) are of medical relevance and deserve detailed chemical characterization. We focus here on 1-[2-(phosphonomethoxy)ethyl]cytosine (PMEC), (S)-1-[3-hydroxy-2-(ph...

Mixed-ligand metal-polymer complexes (MPC) of N-vinylpyrrolidone-N-vinylformamide-N-vinyl iminodiacedic acid (VP-VFA-VIDA) copolymers and diethyldithiocarbamate (DEDTC) as a co-ligand with indium were synthesized under mild conditions and pH close to physiological values. Isolated MPC were characterized by UV, IR, 1H NMR, atomic absorption spectrophotometry, and HPLC. The obtained data implied that the MPC contain 8–10 wt% of (IDA)In(DEDTC) fragments. The optimal conditions for radiochemical synthesis of VP-VFA-VIDA-111In-(DEDTC) metal-polymer complex with mixed ligands were defined. The closest coordination environment of 111In was studied by perturbed angular correlation technique. The obtained data are in good agreement with the information about weight amounts of the corresponding indium MPC.

A novel 1D alternating copper(II) chain complex of the composition {[Cu3(dmg)2(Hdmg)2(4,4′-bpy)]n⋅n[Cu(Hdmg)2(4,4′-bpy)]⋅0.5nH2dmg⋅5nH2O} (H2dmg = dimethylglyoxime, 4,4′-dpy = 4,4′-dipyridine) (1) was synthesized and characterized by elemental analysis, IR, and single-crystal X-ray diffraction. The structure of 1 consists of neutral 1D alternating copper(II) chains [Cu3(dmg)2(Hdmg)2(4,4′-bpy)]n, [Cu(Hdmg)2(4,4′-bpy)] mononuclear units, noncoordinated H2dmg and lattice water molecules. 1D alternating copper(II) chains is built up of trinuclear unit, in which copper ions are linked by three kinds of bridging ligands: dmg, Hdmg and 4,4′-bpy. The authors also studied the electronic structure and orbital energies of 1 by DFT methods, and the results are consistent with UV-vis spectrum.

A new coordination network, namely [Cd(pda)(IP)(H2O)] (1) (H2pda = pyrazine-2,3-dicarboxylic acid and IP= 1-H-imidazo[4,5-f][1,10]-phenanthroline), is explored. A 2D supramolecular net is formed by the hydrogen bonding interactions between IP and coordination water molecule and between carboxylate ligand and water molecule. The luminescence study indicates that the title compound emits bright fluorescence.

A series of mixed ligand complexes of Zn(II) of molecular formula Zn(C15H12N2OX)(C6H4OCHNY) where X= ‒H, ‒CH3, ‒OCH3, Cl, and Y=C7H7, C5H4N, C6H4NO2, (C15H12N2OX) = [3(2′hydroxyphenyl)-5-(4′-X-subs...

Studies on speciation have been done in the mixtures of mixed ligand copper complexes. Three heterogeneous mixtures have been studied, each having one Cu(I) complex and one Cu(II) complex. The Cu(I) complex is [Cu(thu)Cl 0.5H2O] (1) and the Cu(II) complexes are [Cu(L-phen)(bpy) H2O] (2), [Cu(L-tyr)(phn) 2.5H2O] (3), and [Cu(dien)(ina) 4H2O.1/2SO4] (4) (where thu = thiourea, phen = 1,10-phenanthroline, bpy = 2,2′-bipyridine, tyr = tyrosine, dien = diethylenetriamine, and ina = isonicotinate anion). The mixtures have been prepared by mixing the Cu(I) complex with each of the Cu(II) complexes in the ratio of 1:1 by mole percentage. The X-ray absorption fine structure (XAFS) spectra have been recorded at the K-edge of copper in the mixtures as well as in the complexes, separately. The aim of the present work is to make a study of the different methods of speciation using XAFS, viz., principal component analysis (PCA) and the target transformation (TT) method, the linear combination fitting (LCF) meth...

To study the spectral behavior of Ti(IV) complexes with sulfur donors, several new nano-sized mixed ligand complexes of Ti(IV) have been synthesized by the reaction of titanium(IV) salts with 3(2′-...

Four new mixed-ligand complexes of lead(II) hexafluoroacetylacetonate (hfa) were synthesized and characterized by elemental analyses, IR, 1H and 13C NMR spectroscopy. The single-crystal structure of [Pb2(phen)4(hfa)2(μ-NO3)2] (1) shows the complex to be a dimeric unit as a result of nitrate bridging. The coordination number of Pb(II) is eight with four N-donors from a “phen” and four O-donors from the hexafluoroacetylacetonate and nitrate ligands. This dimeric complex is the first fluorine β-diketonate and nitrate mixed-ligand lead(II) complex that has been characterized by X-ray structural analysis. The supramolecular features in this complex are controlled by weak directional intermolecular interactions and aromatic π–π stacking interactions.

A series of lanthanide(III) complexes Ln 2 (HL)(L)(iso)(H 2 O) 4 (where Ln = La(III), Pr(III), Nd(III), Sm(III), Eu(III), Gd(III), Tb(III), Dy(III), Er(III) and H 3 L = N-(2-propionic acid)-salicyloyl hydrazone, Hiso = isonicotinic acid) have been synthesized in ethanol-water mixture and characterized on the basis of elemental analyses, molar conductance, IR, UV-vis spectra, X-ray powder diffraction, and the structures of the complexes were speculated. Inhibiting activities of six complexes against coliform were investigate by turbidimetry/spectrometry and the results showed that all these complexes possessed good antibacterial activities against coliform.

Reactions of pentapseudohalonitrosyl ferrate(II) with β-diketones formed complexes of the type, [Fe(X)3(NO)(L–L)] where X = CN−, NCO− and and L–L = acetylacetonate(acac) and benzoylacetonate (bzac). These compounds have been characterized by elemental analysis, molar conductance, magnetic susceptibility measurements, IR, electronic spectra and thermal gravimetric analysis. Molecular modeling studies have been carried out for structural analysis of some complexes using Hyperchem release 7.52 professional version.