1. Triclosan exposure, transformation, and human health effects
- Author
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Lisa M. Weatherly and Julie A. Gosse
- Subjects
0301 basic medicine ,business.product_category ,Hand Sanitizers ,Health, Toxicology and Mutagenesis ,Population ,Mouthwashes ,010501 environmental sciences ,Soaps ,Toxicology ,01 natural sciences ,Article ,Food and drug administration ,03 medical and health sciences ,chemistry.chemical_compound ,Human health ,Hand sanitizer ,Environmental health ,Animals ,Humans ,Medicine ,education ,0105 earth and related environmental sciences ,education.field_of_study ,Personal care ,Toothpaste ,business.industry ,fungi ,Antimicrobial ,Triclosan ,030104 developmental biology ,chemistry ,Anti-Infective Agents, Local ,Environmental Pollutants ,business ,Toothpastes - Abstract
Triclosan (TCS) is an antimicrobial used so ubiquitously that 75% of the U.S.A. population is likely exposed to this compound via consumer goods and personal care products. In September 2016, TCS was banned from soap products following the risk assessment by the U.S.A. Food and Drug Administration (FDA). However, TCS still remains, at high concentrations, in other personal care products such as toothpaste, mouthwash, hand sanitizer, and surgical soaps. Triclosan is readily absorbed into human skin and oral mucosa and found in various human tissues and fluids. The aim of this review was to describe TCS exposure routes and levels as well as metabolism and transformation processes. The burgeoning literature on human health effects associated with TCS exposure, such as reproductive problems was also summarized.
- Published
- 2017