1. Identification of a novel thymidylate kinase activity
- Author
-
Gunnar Pejler, Liya Wang, Junmei Hu Frisk, and Staffan Eriksson
- Subjects
chemistry.chemical_classification ,Deoxythymidine diphosphate ,010405 organic chemistry ,Intracellular Space ,Thymidylate kinase activity ,General Medicine ,010402 general chemistry ,01 natural sciences ,Biochemistry ,Thymidylate kinase ,Cell Line ,0104 chemical sciences ,Kinetics ,Protein Transport ,Enzyme ,chemistry ,Deoxythymidine monophosphate ,Genetics ,Humans ,Molecular Medicine ,DTTP synthesis ,Nucleoside-Phosphate Kinase - Abstract
Thymidylate kinase (TMPK, EC2.7.4.9) is the enzyme that converts deoxythymidine monophosphate (dTMP) to deoxythymidine diphosphate (dTDP) in the synthesis of dTTP, an essential building block of DNA. To date, there is only one gene (
- Published
- 2020
- Full Text
- View/download PDF