1. GIPC: Glycosyl Inositol Phospho Ceramides, the major sphingolipids on earth
- Author
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Sébastien Mongrand, Paul Gouguet, Véronique Germain, Julien Gronnier, and Jean-Luc Cacas
- Subjects
0106 biological sciences ,0301 basic medicine ,Glycosylation ,Very long chain fatty acid ,Plant Science ,Biology ,Ceramides ,Models, Biological ,01 natural sciences ,Cell wall ,03 medical and health sciences ,chemistry.chemical_compound ,Membrane Microdomains ,Plant defense against herbivory ,Animals ,Glycosyl ,Inositol ,Lipid bilayer ,Sphingolipids ,Mini-Review ,Plants ,Sphingolipid ,030104 developmental biology ,chemistry ,Biochemistry ,lipids (amino acids, peptides, and proteins) ,010606 plant biology & botany - Abstract
What are the most abundant sphingolipids on earth? The answer is Glycosyl Inositol Phosphoryl Ceramides (GIPCs) present in fungi and the green lineage. In this review, we discuss the putative role of plant GIPCs in the lipid bilayer asymmetry, in the lateral organization of membrane rafts and in the very long chain fatty acid inter-leaflet coupling of lipids in the plant plasma membrane (PM). A special focus on the structural similarities -and putative functions- of GIPCs is discussed by comparison with animal gangliosides, structural homologs of plant GIPCs.
- Published
- 2016