Search

Your search keyword '"Jenny F. Seligmann"' showing total 1 results
Start Over Author "Jenny F. Seligmann" Publisher informa uk limited
1 results on '"Jenny F. Seligmann"'

1. Can D-Dimer Measurement Reduce the Frequency of Radiological Assessment in Patients Receiving Palliative Imatinib for Gastrointestinal Stromal Tumor (GIST)?

Author

Maria Marples, Simon Lord, Patrick Hamilton, Peter Hall, Mehran Afshar, Dan Stark, Jenny F. Seligmann, and Paul D. Baxter

Subjects
Male, Cancer Research, medicine.medical_specialty, Palliative care, Gastrointestinal Stromal Tumors, Antineoplastic Agents, Kaplan-Meier Estimate, Asymptomatic, Fibrin Fibrinogen Degradation Products, Predictive Value of Tests, medicine, Humans, Stromal tumor, Aged, Proportional Hazards Models, GiST, business.industry, Palliative Care, Imatinib, General Medicine, Middle Aged, Imatinib mesylate, ROC Curve, Oncology, Predictive value of tests, Imatinib Mesylate, Biomarker (medicine), Female, Radiology, medicine.symptom, Tomography, X-Ray Computed, business, medicine.drug
Abstract

Imatinib therapy has improved outcomes in advanced GISTs. Current guidelines suggest monitoring with CT scanning every 12 weeks. There are no validated biomarkers to assist disease evaluation. We identified 50 patients treated with imatinib for GIST in a single tertiary center. We assessed the prognostic value of D-dimers by Cox regression, and the utility as a biomarker for radiological progression (rPD) using receiver-operator curve (ROC) analysis. In asymptomatic patients with D-dimer levels

Published
2015

Catalog

Books, media, physical & digital resources
See catalog results