1. Diagnosis and outcome of pregnancies with prenatally diagnosed fetal dextrocardia
- Author
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Riza Madazli, Selman Gökalp, Mehmet Aytac Yuksel, Mahmut Oncul, and Funda Oztunc
- Subjects
Adult ,congenital, hereditary, and neonatal diseases and abnormalities ,medicine.medical_specialty ,Turkey ,Prenatal diagnosis ,Dextrocardia ,Ultrasonography, Prenatal ,Young Adult ,Pregnancy ,Internal medicine ,otorhinolaryngologic diseases ,medicine ,Humans ,Diaphragmatic hernia ,Survival rate ,Retrospective Studies ,medicine.diagnostic_test ,business.industry ,Incidence ,Pregnancy Outcome ,Obstetrics and Gynecology ,medicine.disease ,Situs inversus ,medicine.anatomical_structure ,Echocardiography ,embryonic structures ,Pediatrics, Perinatology and Child Health ,Cardiology ,Female ,business ,Fetal echocardiography ,Situs solitus - Abstract
To evaluate the incidence, associated cardiac and extracardiac malformations and clinical outcome of fetuses with dextrocardia.A retrospective review of 3556 fetal echocardiograms between 2000 and 2011 revealed 39 cases of dextrocardia. Dextrocardia was defined as right-sided positioning of the fetal heart. Prenatal and postnatal records of the fetuses were reviewed.The incidence was 1.1%. Of the 39 fetuses, 22 were primary dextrocardia and 17 were dextroposition. Diaphragmatic hernia was the most common cause of dextroposition with the incidence of 76%. Of the fetuses with dextroposition 35.5% had a cardiac anomaly. The survival rate of dextroposition was 31.2% and none of the survivors had an associated cardiac anomaly. Primary fetal dextrocardia was most common with situs solitus (45.4%), followed by situs ambiguous (36.3%) and then situs inversus totalis (18.1%). Structural cardiac malformations were found in 100%, 80% and 25% of fetuses with situs ambiguous, solitus and inversus, respectively. Of the dextroposition, 47.6% terminated pregnancy, 14.2% resulted in intrauterine death, 9.5% died after birth, and 28.5% survived.A wide spectrum of complex cardiac malformations are associated with fetal dextrocardia. Fetal echocardiography enables detection of complex cardiac anomalies so that parents can be appropriately counselled.
- Published
- 2014
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