1. Effects of Panax Ginseng Extract on the Benzo(a)Pyrene Metabolizing Enzyime System
- Author
-
J. K. Park, K. Y. Kim, J. H. Ko, F. C. Lee, E. K. Kim, and J. S. Lee
- Subjects
Male ,Health, Toxicology and Mutagenesis ,Panax ,Toxicology ,complex mixtures ,chemistry.chemical_compound ,Ginseng ,GINSENG EXTRACT ,Benzo(a)pyrene ,Asian country ,Animals ,Glutathione transferase activity ,Glutathione Transferase ,Epoxide Hydrolases ,Pharmacology ,Korea ,Plants, Medicinal ,Chemical Health and Safety ,Ethanol ,Plant Extracts ,Public Health, Environmental and Occupational Health ,food and beverages ,Rats, Inbred Strains ,General Medicine ,Rats ,Cytosol ,chemistry ,Biochemistry ,Pyrene ,Aryl Hydrocarbon Hydroxylases - Abstract
Ethanol extract of Panax ginseng C. A. Meyer, which has been used for centuries as a tonic in Asian countries, exhibited a selective induction of epoxide hydratase and cytosolic glutathione transferase activity without the concurrent induction of aryl hydrocarbon hydroxylase activity. Thus, Panax ginseng appears to have the potential to alter the metabolic patterns of benzo(a)pyrene and its reactive metabolites.
- Published
- 1987