1. Viral Antibody Titres in HBs Antigen-Positive and -Negative Chronic Active Hepatitis
- Author
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F. B. Crimmins, Sheila Sherlock, Howard C. Thomas, M. Ross, G. Ash, and D M Adams
- Subjects
Adult ,Male ,Adolescent ,Human leukocyte antigen ,Antibodies, Viral ,Rubella ,Hepatitis ,Liver disease ,medicine ,Humans ,Aged ,Hepatitis B Surface Antigens ,biology ,business.industry ,Chronic Active ,Liver Diseases ,Complement Fixation Tests ,Gastroenterology ,virus diseases ,Hemagglutination Inhibition Tests ,Middle Aged ,Hepatitis B ,medicine.disease ,Complement fixation test ,Virology ,Antibodies, Antinuclear ,Chronic Disease ,Immunology ,biology.protein ,Female ,Antibody ,business - Abstract
A comparative study of antibody titres to nine common viruses has been carried out in hepatitis B surface (HBs) antigen-positive and -negative chronic active liver disease. The results show that increased titres of antibody to morbilli virus by complement fixation and to rubella by haemagglutination inhibition are found in HBs antigen-negative but not in HBs antigen-positive chronic active liver disease. There was a significant association of increased morbilli but not of rubella virus antibody titres with the presence of high-titre nuclear antibodies (ANA) but no association with smooth-muscle antibody or the presence of HLA-B8.
- Published
- 1980
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