1. The impact of fetal gender and ethnicity on the risk of spontaneous preterm delivery in women with symptoms of preterm labor.
- Author
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Wilms FF, Vis JY, Oudijk MA, Kwee A, Porath MM, Scheepers HC, Spaanderman ME, Bloemenkamp KW, Bolte AC, Bax CJ, Cornette JM, Duvekot JJ, Nij Bijvanck BW, Eijck Jv, Franssen MT, Sollie KM, Vandenbussche FP, Woiski MD, van der Post JA, Bossuyt PM, Opmeer BC, Mol BW, and van Baaren GJ
- Subjects
- Adult, Cervical Length Measurement statistics & numerical data, Chi-Square Distribution, Female, Fetal Development, Fibronectins analysis, Gestational Age, Humans, Male, Pregnancy, Prospective Studies, Risk, Sex Distribution, White People ethnology, Obstetric Labor, Premature ethnology, Premature Birth ethnology, Sex Factors
- Abstract
Objective: The objective of this study is to evaluate the relation among fetal gender, ethnicity, and preterm labor (PTL) and preterm delivery (PTD)., Methods: A secondary analysis was performed of a prospective cohort study including women with symptoms of PTL between 24 and 34 weeks. The proportion of women carrying a male or female fetus at the onset of PTL was calculated. Gestational age at delivery and risk of PTD of both fetal genders was compared and interaction of fetal gender and maternal ethnicity on the risk of PTD was evaluated., Results: Of the 594 included women, 327 (55%) carried a male fetus. Median gestational age at delivery in women pregnant with a male fetus was 37 5/7 (IQR 34 4/7-39 1/7) weeks compared with 38 1/7 (IQR 36 0/7-39 5/7) weeks in women pregnant with a female fetus (pā=ā0.032). The risk of PTD did not differ significantly. In Caucasians, we did find an increased risk of PTD before 37 weeks in women pregnant with a male fetus (OR 1.9 (95% CI 1.2-3.0))., Conclusions: The majority of women with PTL are pregnant with a male fetus and these women deliver slightly earlier. Race seems to affect this disparity.
- Published
- 2016
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