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A new flavonolignan, sonyamandin (1) , along with other known compounds was isolated from the aerial parts and seeds extracts of Silybum marianum (milk thistle) collected from Jordan. The known ones are ursolic acid (2) , oleanolic acid (3) , maslinic acid (4), oleic acid (5) , β-sitosterol (6) , β-, sitosteryl glucoside (7), apigenin (8) , kaempferol-3-O-rhamnoside (9) , apigenin-7-O-β-D-glycoside (10) , isosylibin A (11) , isosylibin B (12), and silybin B (13) . The absolute stereochemistry of 1 was confirmed by 2D NMR and CD analysis.

Phytochemical investigation of the aerial parts and latex of Pergularia tomentosa from Jordan, utilizing column chromatography accompanied with NMR (1 & 2D), IR, UV, and HR-ESI-Mass spectroscopy have led to the isolation and characterization of two new compounds, pergularol (1) and 3-O-acetyl-28-hydroxytaraxasterol (2) for the first time along with other ten known compounds including linoleic acid (3) , 3'-didehydroafroside (4) , apigenin (5) , β-sitosteryl glucoside (6) , luteolin (7) , apigenin 7-(6''-crotonoyl)glucoside (8) , 3'-O-β-glucopyranosylcalotropin (9) , apigenin-7-O-β-D-glycoside (10) , pergularine A (11) , taraxasterol (12) . Compound (8) is isolated for the first time from Pergularia genus.

Two new cardenolides, named ischarin and ischaridin in addition to 10 known compounds, were isolated from Calotropis procera Ait. (Asclepiadaceae), growing wild in Jordan. Their structures were established mainly by the extensive application of one- and two-dimensional (1)H and (13)C-NMR spectroscopy.