1. Two new daphnane diterpenes from the roots of Stelleropsis tianschanica.
- Author
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Zhao D, Shi LL, Guo XF, Ma GX, Han JW, Yang JS, Xu JG, and Zhang J
- Subjects
- Antineoplastic Agents, Phytogenic chemistry, Cell Line, Tumor, Drug Screening Assays, Antitumor, Drugs, Chinese Herbal chemistry, Humans, Magnetic Resonance Spectroscopy, Models, Molecular, Molecular Structure, Antineoplastic Agents, Phytogenic pharmacology, Diterpenes chemistry, Diterpenes pharmacology, Plant Roots chemistry
- Abstract
Two new daphnane diterpenes named tianchaterpenes A and B were isolated from the roots of Stelleropsis tianschanica. Their structures were elucidated on the basis of chemical and spectral analysis, including 1D, 2D NMR analyses and HRESIMS. Compounds 1 and 2 were evaluated for their cytotoxic activities against HeLa and HCT-8 cell lines. The results showed that all compounds displayed weak cytotoxicities to the HeLa cells and were inactive to the HCT-8 cells.
- Published
- 2018
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