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4 results on '"Congiu C"'

1. Synthesis and biological activity of some pyrrole derivatives. I.

Author

Cocco MT, Congiu C, Maccioni A, Plumitallo A, Schivo ML, and Palmieri G

Subjects
Anti-Bacterial Agents, Candida albicans drug effects, Chemical Phenomena, Chemistry, Escherichia coli drug effects, Magnetic Resonance Spectroscopy, Microbial Sensitivity Tests, Pyrroles pharmacology, Staphylococcus aureus drug effects, Anti-Infective Agents chemical synthesis, Pyrroles chemical synthesis
Abstract

The synthesis of some 5-substituted 2-amino-3-cyano (and 3-carboethoxy)pyrroles is described starting from the cyano- and carboethoxyacetomidines and the alpha-halogeno ketones. The compounds tested in vitro as antimicrobial agents did not show any significative activity.

Published
1988

2. Synthesis and antimicrobial activity of some pyrrole derivatives. II: 2-(2'-acylhydrazino)-3-ethoxycarbonyl-5-aryl (or alkyl)- pyrrole derivatives.

Author

Cocco MT, Congiu C, Maccioni A, Schivo ML, and Palmieri G

Subjects
Anti-Bacterial Agents, Anti-Infective Agents pharmacology, Candida albicans drug effects, Chemical Phenomena, Chemistry, Hydrazines pharmacology, Magnetic Resonance Spectroscopy, Pyrroles pharmacology, Staphylococcus aureus drug effects, Anti-Infective Agents chemical synthesis, Hydrazines chemical synthesis, Pyrroles chemical synthesis
Abstract

A series of 2-(2'-acylhydrazino)-3-ethoxycarbonyl-3-aryl (or alkyl)-pyrrole derivatives was synthesized and submitted to in vitro microbiological screening. Most derivatives showed considerable antibacterial and antifungal activities.

Published
1988

3. Synthesis and antimicrobial activity of some pyrrole derivatives. III--2-(4-arylpiperazino)-3-ethoxycarbonyl-5-aryl-pyrrole derivatives.

Author

Cocco MT, Congiu C, Maccioni A, Schivo ML, De Logu A, and Palmieri G

Subjects
Anti-Bacterial Agents pharmacology, Bacteria drug effects, Chemical Phenomena, Chemistry, Microbial Sensitivity Tests, Piperazines pharmacology, Pyrroles pharmacology, Anti-Bacterial Agents chemical synthesis, Piperazines chemical synthesis, Pyrroles chemical synthesis
Abstract

The synthesis of 3-ethoxycarbonyl-5-aryl-pyrrole derivatives with an arylpiperazine group in position 2 is described. The in vitro biological investigation showed that compound (XVIII) had considerable antibacterial activity against gram-positive microorganisms and antifungal activity against Candida rugosa, while the other compounds did not show any significative activity.

Published
1988

4. Synthesis and antifungal activities of N-arylideneaminoimidazole derivatives.

Author

Cocco MT, Congiu C, Plumitallo A, Schivo ML, and Palmieri G

Subjects
Bacteria drug effects, Candida albicans drug effects, Chemical Phenomena, Chemistry, Imidazoles pharmacology, Microbial Sensitivity Tests, Antifungal Agents chemical synthesis, Imidazoles chemical synthesis
Abstract

The synthesis and microbiological activities of 1-arylideneaminoimidazole derivatives are reported. Antimicrobial data show that some of the tested imidazoles exhibited an interesting activity on Candida albicans.

Published
1987
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