Search

Introduction: Despite the fact that zinc deficiency is asymptomatic, its incidence is rising over the world, with no visible clinical manifestation. Mineral and vitamin supplementation to prevent the inflammatory response is a major concern during the COVID-19 pandemic. Zinc may play a role in the development of a stronger immunological response. Nonetheless, there is insufficient information to investigate the benefits of zinc on its own. The impact of zinc deficiency on the severity of COVID-19 infection will be discussed in this systematic study. Material and Methods: We used the search phrases "COVID-19" or "SARS-CoV-2" and "Zinc Deficiency" to look for publications published between 2020 and April 2021 in scholar google, PubMed, SCOPUS, and Proquest. All of the information was examined qualitatively. Results: There are three papers that discuss the benefits of zinc and indicate that zinc deficiency has a key influence in the severity of COVID-19. According to one study, there is no link between zinc deficiency and COVID-19 severity. Conclusions: COVID-19 infection is linked to low zinc levels in the blood. It may become a risk factor for COVID-19 severity or a contributing factor that goes unnoticed in regular practice. Zinc supplementation or zinc baseline serum may play a role in determining potential daily supplementation and treatment for patients at risk of zinc insufficiency in the COVID-19 group in RCT and better design studies.

Background: Only a few published studies have directly demonstrated the effects of local soy isoflavone on the post-menopausal vaginal maturation index. This study focused on the effect of 24 weeks of local soy isoflavone (67,5 mg) consumption to improve the post-menopausal vaginal maturation index. Material and Methods: 50 post-menopausal women were randomly assigned to a double-blind clinical trial to receive cowpea (Vigna unguiculata) powder treatment (n=25) and placebo (n=23). Vaginal cytology (maturation index, maturation value) was evaluated at pre and post-treatment in Anatomy Pathology Laboratories. Collected data were analyzed by using the analysis of covariant (ANOVA) method. Result: There is no difference in maturation vaginal index between the treatment and the placebo group. The treatment was not significantly improved the vaginal maturation index (p