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2 results on '"O, Endoh"'

1. [A case of cardiac myxoma with multiple brain hemorrhage].

Author

Oyama H, Nakayama M, Ikeda A, Maeda M, Miyahara T, Inoue S, Sakurai H, Murayama H, Hasegawa H, Iizuka H, Endoh O, and Shibuya M

Subjects
Brain diagnostic imaging, Heart Neoplasms complications, Humans, Male, Methicillin Resistance, Middle Aged, Myxoma complications, Radiography, Sepsis etiology, Staphylococcal Infections etiology, Staphylococcus aureus, Heart Neoplasms pathology, Intracranial Hemorrhages etiology, Myxoma pathology, Neoplastic Cells, Circulating pathology
Abstract

A case of cardiac myxoma with multiple brain hemorrhage is reported. A 57-year-old male had complained of lower abdominal pain, diarrhea and fever for 3 days. On admission, he was in a condition of disseminated intravascular coagulation and sepsis. An abdominal CT scan showed infarction in the right kidney and spleen and an echocardiogram also showed myxoma in the left atrium. Although he presented no neurological symptoms, the brain CT showed multiple brain hemorrhage in the bilateral brain hemispheres. Total resection of the tumor was carried out for the improvement of the patient's general condition. Vimentin, S-100 protein and neuron specific enolase was positive in immunological staining and the pathological diagnosis was myxoma. Postoperative recovery of consciousness was poor and left hemiparesis developed. CT showed the increase of hematoma but angiography showed no cerebral aneurysm. The symptoms improved with conservative therapy. However the enhanced lesion remained in the right parietal lobe and an operation was performed 5 months later. The myxoma cell could not be found in the pathological examination, so tumor embolism, cerebral infarction, hemorrhagic infarction due to DIC, hematoma enlargement caused by heparinization during operation were suspected to have occurred in this order without tumor growth.

Published
2001

2. [A case of central nervous system anomalies (agenesis of corpus callosum, colpocephaly, hydrocephalus, congenital dermal sinus) associated with congenital heart disease(double-outlet right ventricle, complete endocardial cushion defect, atrial septal defect, pulmonary arterial stenosis, patent ductus arteriosus)].

Author

Oyama H, Numaguchi A, Sakurai H, Ichihara K, Ikeda A, Matsushima M, Maeda M, Inoue S, Iizuka H, Endoh O, and Shibuya M

Subjects
Agenesis of Corpus Callosum, Cerebral Ventricles abnormalities, Constriction, Pathologic, Double Outlet Right Ventricle complications, Ductus Arteriosus, Patent complications, Endocardial Cushion Defects complications, Female, Heart Septal Defects, Atrial complications, Humans, Hydrocephalus complications, Infant, Newborn, Pulmonary Artery pathology, Spina Bifida Occulta, Abnormalities, Multiple, Central Nervous System abnormalities, Heart Defects, Congenital complications
Abstract

A case of central nervous system anomalies(agenesis of corpus callosum, colpocephaly, hydrocephalus, congenital dermal sinus) associated with congenital heart disease(double-outlet right ventricle, complete endocardial cushion defect, atrial septal defect, pulmonary arterial stenosis, patent ductus arteriosus) is reported. Female patient had been already diagnosed as hydrocephalus during pregnancy and ventricular drainage was performed soon after the delivery. Prostaglandin E 1 was also applied for heart disease, but saturation of O2 decreased to 80% on arterial blood gas analysis. Blalock-Taussig operation and ligation of ductus arteriosus was done 41 days after the delivery and ventricle-peritoneal shunt was also made for the progressive hydrocephalus on the same day. Chromosome analysis showed no abnormality. The genesis of this complicated brain and heart anomaly is discussed from the viewpoint of neural crest cell abnormality.

Published
2001

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