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This paper presents a novel machine reading comprehension model based on deep learning techniques in Chinese environment. In our manner, the training process can be performed using a general-level GPU, and the convergence of the training process can be accelerated for a shorter period of time. In the architectural design, two main constituting parts include Self-Attention Mechanism and Convolutional Neural Networks. To enhance the interaction between an article and questions, we carry out the operation of Context-Query Attention twice, so that our model is more effectively for acquiring the information of the questions related to the article and converges faster while training. In the experiment, we adopt the Delta Reading Comprehension Dataset for model evaluation in Chinese environment. The experimental results reveal that our model is able to reach the accuracy of 64.9% for EM and 79.0% for Fl. The convergence time is less than 1 hour using the Titan XP GPU, and the memory usage is comparatively lower. The training performance is about 3 times faster than other models with state- of-the-art architecture.

We report on a light-actuated digital microfluidics platform for real-time, isothermal helicase-dependent polymerase chain reaction (PCR). This platform is used to detect Herpes Simplex Virus Type 1 (HSV-1). Reagents in droplets are individually addressed, mixed, transported and arrayed on-chip before the PCR process. 16 droplets were formed from mixing 400 nl PCR master mix droplets with 35 nl HSV-1 viral lysate droplets, arrayed into a 4×4 matrix, and amplified simultaneously, all on chip. Amplification and detection of HSV-1 can be achieved within 45 minutes. No cross contamination was observed.

This paper presents the shaping of polydimethylsiloxane (PDMS) droplet on a flexible polyethylene (PE) membrane and the associated fabrication process of PDMS ellipsoidal micro-lens array (MLA). This design enlarges the viewing field and has better resolution than spherical MLA because the presented MLA is on a curved substrate and the ellipsoidal lens improves images. The PE membrane coated with polytetrafluoroethylene (Teflon® AF) is covered on a flexible printed circuit (FPC) board. PDMS droplets are dispensed on this membrane. Due to diagonally distributed dielectrophoresis force caused by four-quarter circular electrode pairs, the PDMS droplets deform as part of ellipsoid. Ellipsoidal micro-lens arranging in two orthogonal orientations are created by applying two couples of bias voltage on different electrode pairs. The length of the major axis is different with applied bias voltage. After curing PDMS droplets, the ellipsoidal MLA on flexible membrane is manufactured.