1. Classification and Clustering of Human Sperm Swimming Patterns
- Author
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Moshe Kam, Leonardo F. Urbano, Puneet Masson, Matthew VerMilyea, Chizhong Wang, and Ji-won Choi
- Subjects
0209 industrial biotechnology ,Computer science ,business.industry ,Pattern recognition ,02 engineering and technology ,Subset search ,Sperm ,030218 nuclear medicine & medical imaging ,Artificial bee colony algorithm ,03 medical and health sciences ,020901 industrial engineering & automation ,0302 clinical medicine ,Iterative search ,Artificial intelligence ,Cluster analysis ,business ,human activities ,Sperm motility - Abstract
The principal observed progressive swim types of sperm cells are linear mean and circular swim. Using motility characteristic parameters produced by CASA systems, we perform a parameter subset search to produce distinct clusters of the different swim types. For this task, the artificial bee colony algorithm (an iterative search algorithm modeled after the collective behavior of bees) and the well-studied k-means clustering algorithm were used on simulated and human sperm swim data. The result is distinct clusters with features of each types of swim. The clustering approach displays potential as a tool for automated sperm swim subpopulation analysis.
- Published
- 2018
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