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Ultrasound (US) is the primary imaging technique for the diagnosis of thyroid cancer. However, accurate identification of nodule malignancy is a challenging task that can elude less-experienced clinicians. Recently, many computer-aided diagnosis (CAD) systems have been proposed to assist this process. However, most of them do not provide the reasoning of their classification process, which may jeopardize their credibility in practical use. To overcome this, we propose a novel deep learning (DL) framework called multi-attribute attention network (MAA-Net) that is designed to mimic the clinical diagnosis process. The proposed model learns to predict nodular attributes and infer their malignancy based on these clinically-relevant features. A multi-attention scheme is adopted to generate customized attention to improve each task and malignancy diagnosis. Furthermore, MAA-Net utilizes nodule delineations as nodules spatial prior guidance for the training rather than cropping the nodules with additional models or human interventions to prevent losing the context information. Validation experiments were performed on a large and challenging dataset containing 4554 patients. Results show that the proposed method outperformed other state-of-the-art methods and provides interpretable predictions that may better suit clinical needs. [ABSTRACT FROM AUTHOR]

Fuzzy c-means (FCM) algorithms with spatial information have been widely applied in the field of image segmentation. However, most of them suffer from two challenges. One is that the introduction of fixed or adaptive single neighboring information with narrow receptive field limits contextual constraints leading to clutter segmentations. The other is that the incorporation of superpixels with wide receptive field enlarges spatial coherency leading to block effects. To address these challenges, we propose fuzzy STUDENT’S t-distribution model based on richer spatial combination (FRSC) for image segmentation. In this article, we make two significant contributions. The first is that both the narrow and wide receptive fields are integrated into the objective function of FRSC, which is convenient to mine image features and distinguish local difference. The second is that the rich spatial combination under STUDENT’S t-distribution ensures that spatial information is introduced into the updated parameters of FRSC, which is helpful in finding a balance between the noise-immunity and detail-preservation. Experimental results on synthetic and publicly available images further demonstrate that the proposed FRSC addresses successfully the limitations of FCM algorithms with spatial information, and provides better segmentation results than state-of-the-art clustering algorithms. [ABSTRACT FROM AUTHOR]

This study presents a high-accuracy, efficient, and physically induced method for 3D point cloud registration, which is the core of many important 3D vision problems. In contrast to existing physics-based methods that merely consider spatial point information and ignore surface geometry, we explore geometry aware rigid-body dynamics to regulate the particle (point) motion, which results in more precise and robust registration. Our proposed method consists of four major modules. First, we leverage the graph signal processing (GSP) framework to define a new signature, i.e., point response intensity for each point, by which we succeed in describing the local surface variation, resampling keypoints, and distinguishing different particles. Then, to address the shortcomings of current physics-based approaches that are sensitive to outliers, we accommodate the defined point response intensity to median absolute deviation (MAD) in robust statistics and adopt the X84 principle for adaptive outlier depression, ensuring a robust and stable registration. Subsequently, we propose a novel geometric invariant under rigid transformations to incorporate higher-order features of point clouds, which is further embedded for force modeling to guide the correspondence between pairwise scans credibly. Finally, we introduce an adaptive simulated annealing (ASA) method to search for the global optimum and substantially accelerate the registration process. We perform comprehensive experiments to evaluate the proposed method on various datasets captured from range scanners to LiDAR. Results demonstrate that our proposed method outperforms representative state-of-the-art approaches in terms of accuracy and is more suitable for registering large-scale point clouds. Furthermore, it is considerably faster and more robust than most competitors. Our implementation is publicly available at https://github.com/zikai1/GraphReg. [ABSTRACT FROM AUTHOR]

Fitting ellipses from unrecognized data is a fundamental problem in computer vision and pattern recognition. Classic least-squares based methods are sensitive to outliers. To address this problem, in this paper, we present a novel and effective method called hierarchical Gaussian mixture models (HGMM) for ellipse fitting in noisy, outliers-contained, and occluded settings on the basis of Gaussian mixture models (GMM). This method is crafted into two layers to significantly improve its fitting accuracy and robustness for data containing outliers/noise and has been proven to effectively narrow down the iterative interval of the kernel bandwidth, thereby speeding up ellipse fitting. Extensive experiments are conducted on synthetic data including substantial outliers (up to 60%) and strong noise (up to 200%) as well as on real images including complex benchmark images with heavy occlusion and images from versatile applications. We compare our results with those of representative state-of-the-art methods and demonstrate that our proposed method has several salient advantages, such as its high robustness against outliers and noise, high fitting accuracy, and improved performance. [ABSTRACT FROM AUTHOR]

Clustering algorithms by minimizing an objective function share a clear drawback of having to set the number of clusters manually. Although density peak clustering is able to find the number of clusters, it suffers from memory overflow when it is used for image segmentation because a moderate-size image usually includes a large number of pixels leading to a huge similarity matrix. To address this issue, here we proposed an automatic fuzzy clustering framework (AFCF) for image segmentation. The proposed framework has threefold contributions. First, the idea of superpixel is used for the density peak (DP) algorithm, which efficiently reduces the size of the similarity matrix and thus improves the computational efficiency of the DP algorithm. Second, we employ a density balance algorithm to obtain a robust decision-graph that helps the DP algorithm achieve fully automatic clustering. Finally, a fuzzy c-means clustering based on prior entropy is used in the framework to improve image segmentation results. Because the spatial neighboring information of both the pixels and membership are considered, the final segmentation result is improved effectively. Experiments show that the proposed framework not only achieves automatic image segmentation, but also provides better segmentation results than state-of-the-art algorithms. [ABSTRACT FROM AUTHOR]

Morphological reconstruction (MR) is often employed by seeded image segmentation algorithms such as watershed transform and power watershed, as it is able to filter out seeds (regional minima) to reduce over-segmentation. However, the MR might mistakenly filter meaningful seeds that are required for generating accurate segmentation and it is also sensitive to the scale because a single-scale structuring element is employed. In this paper, a novel adaptive morphological reconstruction (AMR) operation is proposed that has three advantages. First, AMR can adaptively filter out useless seeds while preserving meaningful ones. Second, AMR is insensitive to the scale of structuring elements because multiscale structuring elements are employed. Finally, the AMR has two attractive properties: monotonic increasingness and convergence that help seeded segmentation algorithms to achieve a hierarchical segmentation. Experiments clearly demonstrate that the AMR is useful for improving performance of algorithms of seeded image segmentation and seed-based spectral segmentation. Compared to several state-of-the-art algorithms, the proposed algorithms provide better segmentation results requiring less computing time. [ABSTRACT FROM AUTHOR]

A great number of improved fuzzy c-means (FCM) clustering algorithms have been widely used for grayscale and color image segmentation. However, most of them are time-consuming and unable to provide desired segmentation results for color images due to two reasons. The first one is that the incorporation of local spatial information often causes a high computational complexity due to the repeated distance computation between clustering centers and pixels within a local neighboring window. The other one is that a regular neighboring window usually breaks up the real local spatial structure of images and thus leads to a poor segmentation. In this work, we propose a superpixel-based fast FCM clustering algorithm that is significantly faster and more robust than state-of-the-art clustering algorithms for color image segmentation. To obtain better local spatial neighborhoods, we first define a multiscale morphological gradient reconstruction operation to obtain a superpixel image with accurate contour. In contrast to traditional neighboring window of fixed size and shape, the superpixel image provides better adaptive and irregular local spatial neighborhoods that are helpful for improving color image segmentation. Second, based on the obtained superpixel image, the original color image is simplified efficiently and its histogram is computed easily by counting the number of pixels in each region of the superpixel image. Finally, we implement FCM with histogram parameter on the superpixel image to obtain the final segmentation result. Experiments performed on synthetic images and real images demonstrate that the proposed algorithm provides better segmentation results and takes less time than state-of-the-art clustering algorithms for color image segmentation. [ABSTRACT FROM AUTHOR]

As fuzzy c-means clustering (FCM) algorithm is sensitive to noise, local spatial information is often introduced to an objective function to improve the robustness of the FCM algorithm for image segmentation. However, the introduction of local spatial information often leads to a high computational complexity, arising out of an iterative calculation of the distance between pixels within local spatial neighbors and clustering centers. To address this issue, an improved FCM algorithm based on morphological reconstruction and membership filtering (FRFCM) that is significantly faster and more robust than FCM is proposed in this paper. First, the local spatial information of images is incorporated into FRFCM by introducing morphological reconstruction operation to guarantee noise-immunity and image detail-preservation. Second, the modification of membership partition, based on the distance between pixels within local spatial neighbors and clustering centers, is replaced by local membership filtering that depends only on the spatial neighbors of membership partition. Compared with state-of-the-art algorithms, the proposed FRFCM algorithm is simpler and significantly faster, since it is unnecessary to compute the distance between pixels within local spatial neighbors and clustering centers. In addition, it is efficient for noisy image segmentation because membership filtering are able to improve membership partition matrix efficiently. Experiments performed on synthetic and real-world images demonstrate that the proposed algorithm not only achieves better results, but also requires less time than the state-of-the-art algorithms for image segmentation. [ABSTRACT FROM AUTHOR]