1. Inhibition of Amphiphilic N-Alkyl-O-carboxymethyl Chitosan Derivatives on Alternaria macrospora .
- Author
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Liu Q, Zhang J, Li D, Lang J, Zai S, Hao J, and Wang X
- Subjects
- China, Chitosan agonists, Chitosan pharmacology, Plant Diseases, Schiff Bases, Alternaria drug effects, Antifungal Agents pharmacology, Chitosan analogs & derivatives
- Abstract
Cotton leaf spot (Alternaria macrospora) is a widespread disease that occurs in the main cotton-producing area of China. In managing this disease, a novel chitosan-based biopesticide, an amphiphilic N-alkyl-O-carboxymethyl chitosan derivative, was prepared. The product was selected from variations of chitosan with different molecular structures, which were obtained via a two-step reaction. First, carboxymethyl chitosans with varying molecular sizes were obtained by etherification with chloroacetic acid; then the carboxymethyl chitosan was alkylated with C4-C12 fatty aldehyde through a Schiff-base reaction. This procedure resulted in derivatives of amphiphilic N-alkyl-O-carboxymethyl chitosan, which showed strong antifungal activities against A. macrospora , and the efficacy was determined by its molecular structure.
- Published
- 2018
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