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Objective: To explore the effect of rapid rehabilitation nursing combined with continuous nursing after discharge on patients with cerebral infarction (CI) in recovery period and its influence on motor function, mental state, and quality of life., Methods: From January 2018 to December 2020, 136 patients with CI in recovery period were selected and randomly divided into control group ( n  = 68) and observation group ( n  = 68). The control group was given routine nursing, and the observation group was given rapid rehabilitation nursing combined with continuous nursing after discharge. The general clinical data of the two groups were recorded, and the nursing efficiency, modified Barthel index scale (MBI), stroke patients motor assessment scale (MAS), self-rating anxiety and depression scale (SAS and SDS), and quality of life assessment scale (QLI) were compared between the two groups., Results: The nursing effective rate of the observation group (94.12%, 64/68) was higher than that of the control group (82.35%, 56/68) ( P < 0.05). The MBI score, MAS score, and QLI score in the observation group were higher than those in the control group, while the SAS and SDS scores in the observation group were lower than those in the control group ( P < 0.05)., Conclusion: Rapid rehabilitation nursing combined with continuous nursing after discharge can promote the rapid recovery of patients with CI in recovery period, which can improve the patient's motor function, reduce unhealthy psychology, and improve the quality of life., Competing Interests: The authors declare no conflicts of interest., (Copyright © 2021 Rongxiang Xie et al.)