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What is known and Objective: Aripiprazole has a low risk of extrapyramidal symptoms. Switching to aripiprazole has been reported to improve tardive dyskinesia caused by other medications. The authors report a case and review previous reports of dystonia and dyskinesia associated with aripiprazole. Case summary: We present a case of a 22-year-old man with schizophrenia who experienced dyskinesia and dystonia associated with aripiprazole. Switching from olanzapine to aripiprazole resulted in worsening dyskinesia and new onset of dystonia. The patient's dyskinesia and dystonia improved after switching from aripiprazole to quetiapine therapy. What is new and Conclusion: There were several previous case reports on dyskinesia and dystonia associated with aripiprazole medication. The risk factors for tardive dyskinesia include older age and female sex. However, our case was a male patient who was younger compared with the previous cases and so should have been less at risk for dyskinesia in comparison with the previous cases. The effects of aripiprazole can include tardive movement disorders. Dyskinesia, dystonia and psychotic symptoms were improved with relatively small dose of quetiapine in this case. Whether some second-generation antipsychotics are more effective than others in the treatment of tardive dyskinesia remains unclear. [ABSTRACT FROM AUTHOR]

This study replicated the factor structure of the Parental Bonding Instrument (PBI), and explored the relationships of PBI scores to demographic variables. We investigated the association between parental bonding in the parents measured by the PBI, and lifetime history of depression in their children assessed by the Inventory to Diagnose Depression Lifetime version (IDDL) in a volunteer sample of 239 Japanese workers. In factor analyses with varimax rotation (two-factor solution), the PBI items for both parents showed clear bimodality, and the total variance explained by the two factors was similar to that found in previous Western studies. Subjects with a lifetime history of depression reported a significantly lower score on maternal care than did those without a lifetime history of depression. Without requiring 2 weeks symptom duration on the IDDL, low maternal care was also related to a history of depression. The relationships between PBI scores and age, education, sex of respondent, and sex of parent differed in part from those in Western subjects. These results suggested the following: (1) child-rearing behaviors in non-Western cultures can be, similarly to those in Western cultures, described with the PBI; (2) parental styles, as measured by the PBI, may be associated with depression in non-Western subjects; and (3) sociodemographic influences on PBI scores may be different in subjects with different cultural backgrounds. [ABSTRACT FROM AUTHOR]