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This study investigated 80 strains, which were isolated from Chinese pickles. The preliminary selection carried out by using OD values to study the ability of the strains to resist the low pH (2.0 and 2.5) and bile salt (0.15 and 0.3%). Then the viable count was used for re-screening. The results suggested that the strain JR14 has the best tolerance for both bile salt and acid, which was identified as Lactobacillus plantarum. The antioxidant ability, including the abilities to remove hydroxyl free radicals and superoxide anion radicals, were also studied. The results suggested that the inhibition rate of hydroxyl radical were 29.47, 27.56 and 42.74% for the broth, the supernatant and the cell, respectively. The inhibition rate of superoxide free radicals was 89.38% in growth broth. The results suggested that JR14 has good tolerance in gastrointestinal, and also has certain antioxidant ability. Practical Applications Lactobacillus plantarum JR14 was isolated from Chinese traditional pickle, which could be used for pickle fermentation as probiotics. Application of JR14 would improve the antioxidant properties of the foods. The research provided useful information for the potential use of this strain in foods. [ABSTRACT FROM AUTHOR]

Background. The inhalation anesthetics nitrous oxide (N2O) and isoflurane (ISO) are used in surgical procedures for human infants. Injury to the central nervous system is often accompanied by localization of activated microglia or astrocytosis at the site of injury. The tracer that targets to the peripheral benzodiazepine receptor (PBR), [18F]N-2-(2-fluoroethoxy)benzyl)- N-(4-phenoxypyridin-3-yl)acetamide ([18F]-FEPPA), has been reported as a sensitive biomarker for the detection of neuronal damage/inflammation. Methods. On postnatal day (PND) 5 or 6 rhesus monkey neonates were exposed to a mixture of N2O/oxygen and ISO for 8 hours and control monkeys were exposed to room air. MicroPET/CT images with [18F]-FEPPA were obtained for each monkey 1 day, one week, three weeks, and 6 months after the anesthetic exposure. Results. The radiotracer quickly distributed into the brains of both treated and control monkeys on all scan days. One day after anesthetic exposure, the uptake of [18F]-FEPPA was significantly increased in the temporal lobe. One week after exposure, the uptake of [18F]-FEPPA in the frontal lobe of treated animals was significantly greater than that in controls. Conclusions. These findings suggest that microPET imaging is capable of dynamic detection of inhaled anesthetic-induced brain damage in different brain regions of the nonhuman primate. [ABSTRACT FROM AUTHOR]