1. A Prototypical First-Generation Electronic Cigarette Does Not Reduce Reports of Tobacco Urges or Withdrawal Symptoms among Cigarette Smokers
- Author
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William W. Stoops, Catherine A. Martin, Richard J. Kryscio, Arit M. Harvanko, Joshua A. Lile, and Thomas H. Kelly
- Subjects
Article Subject ,business.industry ,Chain smoking ,First generation ,3. Good health ,law.invention ,Nicotine ,03 medical and health sciences ,0302 clinical medicine ,law ,Environmental health ,Nicotine concentration ,Medicine ,lcsh:H1-99 ,030212 general & internal medicine ,Pack-year ,lcsh:Social sciences (General) ,business ,Electronic cigarette ,030217 neurology & neurosurgery ,Research Article ,medicine.drug - Abstract
It is unknown whether first-generation electronic cigarettes reduce smoking urges and withdrawal symptoms following a 24 h deprivation period. This study tested whether a first-generation electronic cigarette reduces smoking urges and withdrawal symptoms in cigarette smokers. Following 24 h of tobacco deprivation, using a within-subjects design, eight nontreatment seeking tobacco cigarette smokers (3 females) administered 10 puffs from a conventional cigarette or a first-generation electronic cigarette containing liquid with 0, 8 or 16 mg/ml nicotine. Conventional cigarettes ameliorated smoking urges and electronic cigarettes did not, regardless of nicotine concentration. First-generation electronic cigarettes may not effectively substitute for conventional cigarettes in reducing smoking urges, regardless of nicotine concentration.
- Published
- 2017
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