1. Brain activations in speech recovery process after intra-oral surgery: an fMRI study
- Author
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Coriandre Vilain, Alexandre Krainik, Marc Sato, Christian Righini, Georges Bettega, Audrey Acher, Laurent Lamalle, Muriel Brix, Brice Carlot, Pascal Perrier, Arnaud Attyé, GIPSA - Machines parlantes, Gestes oro-faciaux, Interaction Face-à-face, Communication augmentée (GIPSA-MAGIC), Département Parole et Cognition (GIPSA-DPC), Grenoble Images Parole Signal Automatique (GIPSA-lab), Université Pierre Mendès France - Grenoble 2 (UPMF)-Université Stendhal - Grenoble 3-Université Joseph Fourier - Grenoble 1 (UJF)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Centre National de la Recherche Scientifique (CNRS)-Université Pierre Mendès France - Grenoble 2 (UPMF)-Université Stendhal - Grenoble 3-Université Joseph Fourier - Grenoble 1 (UJF)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Centre National de la Recherche Scientifique (CNRS)-Grenoble Images Parole Signal Automatique (GIPSA-lab), Université Pierre Mendès France - Grenoble 2 (UPMF)-Université Stendhal - Grenoble 3-Université Joseph Fourier - Grenoble 1 (UJF)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Centre National de la Recherche Scientifique (CNRS)-Université Pierre Mendès France - Grenoble 2 (UPMF)-Université Stendhal - Grenoble 3-Université Joseph Fourier - Grenoble 1 (UJF)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Centre National de la Recherche Scientifique (CNRS), GIPSA - Perception, Contrôle, Multimodalité et Dynamiques de la parole (GIPSA-PCMD), NSERM U836, équipe 5, Neuro-imagerie fonctionnelle et métabolique, RMN biomédicale : de la cellule à l'homme (RBCH), Université Pierre Mendès France - Grenoble 2 (UPMF)-Université Joseph Fourier - Grenoble 1 (UJF)-CHU Grenoble-DIR CENTRALE DU SSA-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Pierre Mendès France - Grenoble 2 (UPMF)-Université Joseph Fourier - Grenoble 1 (UJF)-CHU Grenoble-DIR CENTRALE DU SSA-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), GIPSA-Services (GIPSA-Services), SFR1 RMN Biomédicale et Neurosciences - Unité IRM Recherche 3T, Grenoble Institut des Neurosciences (GIN), Université Joseph Fourier - Grenoble 1 (UJF)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Joseph Fourier - Grenoble 1 (UJF)-Institut National de la Santé et de la Recherche Médicale (INSERM), SFR1 RMN Biomédicale et Neurosciences - Unité IRM Recherche 3TRM Recherche 3T, Service de chirurgie plastique et maxillofaciale, Université Joseph Fourier - Grenoble 1 (UJF)-CHU Grenoble-Hôpital Michallon, Clinique ORL, Pôle Tête et cou et Chirurgie Réparatrice, Université Joseph Fourier - Grenoble 1 (UJF), CHU Grenoble, Université Joseph Fourier - Grenoble 1 (UJF)-CHU Grenoble, Projet REPARLE - Fondation 'Les Gueules Cassées', International Speech Communication Association, and GIPSA-lab - SFR1 RMN Biomédicale et Neurosciences - CHU Grenoble
- Subjects
medicine.medical_specialty ,Speech production ,sparse-sampling ,Computer science ,medicine.medical_treatment ,[SDV.CAN]Life Sciences [q-bio]/Cancer ,02 engineering and technology ,Superior parietal lobule ,030507 speech-language pathology & audiology ,03 medical and health sciences ,Tongue ,Motor control ,Vowel ,0202 electrical engineering, electronic engineering, information engineering ,medicine ,[SHS.LANGUE]Humanities and Social Sciences/Linguistics ,Speech recovery ,glossectomy ,whole-brain analysis ,[SCCO.NEUR]Cognitive science/Neuroscience ,fMRI ,[SDV.NEU.SC]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Cognitive Sciences ,020206 networking & telecommunications ,[SCCO.LING]Cognitive science/Linguistics ,Surgery ,Neurophonetics ,medicine.anatomical_structure ,Glossectomy ,Neurocomputational speech processing ,Syllable ,0305 other medical science - Abstract
International audience; This study aims at describing cortical and subcortical activation patterns associated with functional recovery of speech production after reconstructive mouth surgery. Our ultimate goal is the understanding of how the brain deals with altered relationships between motor commands and auditory/orosensory feedback, and establishes new inter-articulatory coordination to preserve speech communication abilities. A longitudinal sparse-sampling fMRI study involving orofacial, vowel and syllable production tasks on 9 patients and in three different sessions (one week before, one month and three months after surgery) was conducted. Healthy subjects were recorded in parallel. Results show that for patients in the pre-surgery session, activation patterns are in good agreement with the classical speech production network. Crucially, lower activity in sensorimotor control brain areas during orofacial and speech production movements is observed for patients in all sessions. One month after surgery, the superior parietal lobule is more activated for simple vowel production suggesting a strong involvement of a multimodal integration process to compensate for loss of tongue motor control. Altogether, these results indicate both altered and adaptive sensorimotor control mechanisms in these patients. Index Terms: Neurophonetics, fMRI, speech recovery, motor control, glossectomy, whole-brain analysis, sparse-sampling.
- Published
- 2013