1. The geographic diversity of nontuberculous mycobacteria isolated from pulmonary samples: A NTM-NET collaborative study
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Eefje Jong, Monika Polanova, Kevin L. Winthrop, Tuula Vasankari, Tomasz Jagielski, Diego Domingo, Elia Palenque, Rosine Bauriaud, Miguel Villar, Mateja Janković, Joseph Keane, Rita Macedo, Dick van Soolingen, Renata Walkiewicz, Harald Hoffmann, Jakko van Ingen, Claire Andrejak, Raquel Cias, Frances Jamieson, Rachel Thomson, Sylvia Cardoso Leão, Elvira Richter, Martin J. Boeree, Kristian Ängeby, Charles L. Daley, Nalin Rastogi, Wo Jung Koh, Maryse Fauville-Dufaux, Po-Ren Hsueh, Dimitrios Papaventsis, Natalie Beylis, Rosa Daza, Noel Gibbons, Maria Jesus Ruiz-Serrano, Enrico Tortoli, Tamas Mlinkó, Berit Lange, Rosa Gonzalez, Jaime Esteban, Francis Drobniewski, Nora Szabó, Mar Paez-Peña, Alexander Indra, Heather Milburn, Kozo Morimoto, P. N. Richard Dekhuijzen, Teresa Fernandez, Anabela Santos Silva, Violet N. Chihota, Erica Chimara, Turid Mannsåker, Wouter Hoefsloot, Nora Morcillo, Gavin J. Churchyard, Jeannette Maugein, Dirk Wagner, Sarah E. Totten, Hülya Şimşek, Greg Tyrrell, Theodore K. Marras, Claudio Piersimoni, Enrique Gómez-Mampaso, Juana Cacho, Dorte Bek Folkvardsen, Pascale Bémer, M. Pedro Da Silva, Dept of Medical Microbiology, van Ingen (Jakko), Radboud University Medical Center [Nijmegen]-Radboud University Medical Center [Nijmegen], Departement of Clinical Microbiology, Karolinska Institutet [Stockholm], Laboratoire Central de Microbiologie, Hôpital Purpan [Toulouse], CHU Toulouse [Toulouse]-CHU Toulouse [Toulouse], Service de Bactériologie-Hygiène, Department of Microbiology, CHU Hôtel-Dieu, Lab. Fisica Aplicada, Department of Clinical Microbiology, Centre national de Référence et Laboratoire Tuberculose et Mycobactéries = National Reference Centre of Tuberculosis and Mycobacteria [Brussels] (CNR), Institut Scientifique de Santé Publique [Belgique] - Scientific Institute of Public Health [Belgium] (WIV-ISP), Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP), LPI, Institut Français de Recherche pour l'Exploitation de la Mer (IFREMER), Department of Applied Microbiology [Warsaw], Institute of Microbiology [Warsaw], Faculty of Biology [Warsaw], University of Warsaw (UW)-University of Warsaw (UW)-Faculty of Biology [Warsaw], University of Warsaw (UW)-University of Warsaw (UW), Institut Pasteur de la Guadeloupe, Réseau International des Instituts Pasteur (RIIP), Centro Regionale di Riferimento per i Micobatteri, Ospedale Careggi-Laboratorio di Microbiologia e Virologia, General Directorate of Health, Radboud Univ Nijmegen, Amiens Teaching Hosp, Karolinska Inst, Hop Purpan, CHU Nantes, Natl Hlth Lab Serv, Univ Hosp Getafe, Aurum Inst Hlth Res, Adolfo Lutz Inst, Hosp Clin San Carlos, Hosp Univ Puerta de Hierro, Natl Jewish Hlth, Hosp Univ Princesa, UK Hlth Protect Agcy, IIS Fdn Jimenez Diaz, Sci Inst Publ Hlth, Statens Serum Inst, St James Hosp, Univ Dublin Trinity Coll, Hosp Ramon & Cajal, Hosp Univ Principe Asturias, Asklepios Facbkliniken, Natl Taiwan Univ Hosp, Austrian Agcy Hlth & Food Safety, Univ Warsaw, Ontario Minist Hlth & Long Term Care, Univ Zagreb Med Sch, Univ Witwatersrand, St Jamess Hosp Dublin, Sungkyunkwan Univ Sch Med, Univ Hosp Freiburg, Universidade Federal de São Paulo (UNIFESP), Adm Reg Saude Lisboa & Vale Tejo, Norwegian Inst Publ Hlth, Univ Toronto, Univ Victor Segalen Bordeaux, Guys & St Thomas NHS Fdn Trust, Koranyi Natl Inst TB & Pulmonol, Hosp Dr Antonio Cetrangolo, Fukujuji Hosp, Sotiria Chest Dis Hosp, Hosp 12 Octubre, Hosp Severo Ochoa, United Hosp, Natl Inst TB Resp Dis & Chest Surg, Inst Pasteur Guadeloupe, Natl Reference Ctr Mycobacteria, Hosp Gregorio Maranon, Gen Directorate Hlth Lisbon, Lung Dis Ctr Venda Nova, Refik Saydam Natl Publ Hlth Agcy, Natl Inst Publ Hlth & Environm, Koranyi Natl Inst TB & Resp Med, Greenslopes Private Hosp, Hosp Val dHebron, Ist Sci San Raffaele, Univ Calgary, Natl Inst Hlth & Welf, Med Univ Warsaw, Oregon Hlth & Sci Univ, Univ Freiburg, Laboratoire de Physiologie des Invertébrés (LPI), Physiologie Fonctionnelle des Organismes Marins (PFOM), and Institut Français de Recherche pour l'Exploitation de la Mer (IFREMER)-Institut Français de Recherche pour l'Exploitation de la Mer (IFREMER)
- Subjects
Lung Diseases ,Veterinary medicine ,Mycobacterium bohemicum ,Mycobacterium lentiflavum ,Species distribution ,Global Health ,Poverty-related infectious diseases Infection and autoimmunity [N4i 3] ,Species identification ,Lung ,Nontuberculous mycobacteria ,Mycobacterium interjectum ,0303 health sciences ,Geography ,biology ,Atypical mycobacteria ,Mycobacterium abscessus ,Ecology ,Mycobacterium fortuitum ,Relative distribution ,nontuberculous mycobacteria ,geographical diversity ,Mycobacterium scrofulaceum ,Mycobacterium malmoense ,3. Good health ,Mycobacterium gordonae ,Pathogenesis and modulation of inflammation [N4i 1] ,Mycobacterium kansasii ,NTM ,Worldwide distribution ,Poverty-related infectious diseases Aetiology, screening and detection [N4i 3] ,Pulmonary and Respiratory Medicine ,Mycobacterium xenopi ,Tuberculosis ,Mycobacterium smegmatis ,Mycobacterium simiae ,Mycobacterium Infections, Nontuberculous ,Mycobacterium ,03 medical and health sciences ,Species Specificity ,medicine ,Humans ,Mycobacterium avium complex ,030304 developmental biology ,030306 microbiology ,Poverty-related infectious diseases [N4i 3] ,Respiratory infections ,Geographic diversity ,medicine.disease ,biology.organism_classification ,bacterial infections and mycoses ,[SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology ,Mycobacterium intracellulare ,Pulmonary infections ,Mycobacterium avium - Abstract
German Federal Ministry of Education and Research A significant knowledge gap exists concerning the geographical distribution of nontuberculous mycobacteria (NTM) isolation worldwide.To provide a snapshot of NTM species distribution, global partners in the NTM-Network European Trials Group (NET) framework (www.ntm-net.org), a branch of the Tuberculosis Network European Trials Group (TB-NET), provided identification results of the total number of patients in 2008 in whom NTM were isolated from pulmonary samples. From these data, we visualised the relative distribution of the different NTM found per continent and per country.We received species identification data for 20182 patients, from 62 laboratories in 30 countries across six continents. 91 different NTM species were isolated. Mycobacterium avium complex (MAC) bacteria predominated in most countries, followed by M. gordonae and M. xenopi. Important differences in geographical distribution of MAC species as well as M. xenopi, M. kansasii and rapid-growing mycobacteria were observed.This snapshot demonstrates that the species distribution among NTM isolates from pulmonary specimens in the year 2008 differed by continent and differed by country within these continents. These differences in species distribution may partly determine the frequency and manifestations of pulmonary NTM disease in each geographical location. Radboud Univ Nijmegen, Med Ctr, Dept Pulm Dis, NL-6500 HB Nijmegen, Netherlands Radboud Univ Nijmegen, Med Ctr, Dept Med Microbiol, NL-6500 HB Nijmegen, Netherlands Amiens Teaching Hosp, Dept Resp Dis, Amiens, France Karolinska Inst, Dept Clin Microbiol, Stockholm, Sweden Hop Purpan, Lab Cent Microbiol, Toulouse, France CHU Nantes, Inst Biol, Serv Bacteriol Hyg, F-44035 Nantes 01, France Natl Hlth Lab Serv, Braamfontein, South Africa Univ Hosp Getafe, Dept Microbiol, Getafe, Spain Aurum Inst Hlth Res, Johannesburg, South Africa Adolfo Lutz Inst, Secao Bacteriol, Setor Micobacterias, São Paulo, Brazil Hosp Clin San Carlos, Dept Clin Microbiol, Madrid, Spain Hosp Univ Puerta de Hierro, Dept Microbiol, Madrid, Spain Natl Jewish Hlth, Div Mycobacterial & Resp Infect, Denver, CO USA Hosp Univ Princesa, Dept Microbiol, Madrid, Spain UK Hlth Protect Agcy, Natl Mycobacterium Reference Lab, London, England IIS Fdn Jimenez Diaz, Dept Clin Microbiology, Madrid, Spain Sci Inst Publ Hlth, Natl Reference Ctr TB & Mycobacteria, Brussels, Belgium Statens Serum Inst, Int Reference Lab Mycobacteriol, DK-2300 Copenhagen, Denmark St James Hosp, Dublin 8, Ireland Univ Dublin Trinity Coll, Dublin 2, Ireland Hosp Ramon & Cajal, E-28034 Madrid, Spain Hosp Univ Principe Asturias, Madrid, Spain Asklepios Facbkliniken, Supranat Reference Lab, Inst Microbiol & Lab Med, Gauting, Germany Natl Taiwan Univ Hosp, Dept Lab Med, Taipei, Taiwan Natl Taiwan Univ Hosp, Dept Internal Med, Taipei 100, Taiwan Austrian Agcy Hlth & Food Safety, Vienna, Austria Univ Warsaw, Fac Biol, Inst Microbiol, Dept Appl Microbiol, Warsaw, Poland Ontario Minist Hlth & Long Term Care, Publ Hlth Labs Branch, Toronto, ON, Canada Univ Zagreb Med Sch, Univ Hosp Ctr, Dept Resp Dis, Zagreb, Croatia Univ Witwatersrand, Clin HIV Res Unit, Johannesburg, South Africa St Jamess Hosp Dublin, Dublin, Ireland Sungkyunkwan Univ Sch Med, Samsung Med Ctr, Dept Med, Div Pulm & Crit Care Med, Seoul, South Korea Univ Hosp Freiburg, Ctr Infect Dis & Travel Med, Freiburg, Germany Universidade Federal de São Paulo, Escola Paulista Med, Dept Microbiol Imunol & Parasitol, Disciplina Microbiol, São Paulo, Brazil Adm Reg Saude Lisboa & Vale Tejo, Dept Publ Hlth, Publ Hlth Lab Mycobacteriol TB, Lisbon, Portugal Norwegian Inst Publ Hlth, Div Infect Dis Control, Oslo, Norway Univ Toronto, Univ Hlth Network, Joint Div Respirol, Toronto, ON, Canada Univ Toronto, Mt Sinai Hosp, Dept Med, Toronto, ON M5G 1X5, Canada Univ Victor Segalen Bordeaux, Lab Bacteriol, Bordeaux, France Guys & St Thomas NHS Fdn Trust, Dept Resp Med, London, England Koranyi Natl Inst TB & Pulmonol, Budapest, Hungary Hosp Dr Antonio Cetrangolo, Programa Control TB Prov Buenos Aires, Lab Referencia, Buenos Aires, Brazil Fukujuji Hosp, Japan AntiTB Assoc, Tokyo, Japan Sotiria Chest Dis Hosp, Natl Mycobacteria Reference Lab, Athens, Greece Hosp 12 Octubre, Dept Microbiol, E-28041 Madrid, Spain Hosp Severo Ochoa, Madrid, Spain United Hosp, Reg Reference Mycobacteria Lab, Ancona, Italy Natl Inst TB Resp Dis & Chest Surg, Vysne Hagy, Slovakia Inst Pasteur Guadeloupe, Unite TB & Mycobacteries, WHO Supranat TB Reference Lab, Abymes, Guadeloupe Natl Reference Ctr Mycobacteria, Borstel, Germany Hosp Gregorio Maranon, Serv Microbiol Clin & Enfermedades Infecciosas, Madrid, Spain Gen Directorate Hlth Lisbon, Amadora, Portugal Lung Dis Ctr Venda Nova, Amadora, Portugal Univ Witwatersrand, Johannesburg, South Africa Refik Saydam Natl Publ Hlth Agcy, Natl TB Reference Lab, Ankara, Turkey Natl Inst Publ Hlth & Environm, NL-3720 BA Bilthoven, Netherlands Koranyi Natl Inst TB & Resp Med, Budapest, Hungary Greenslopes Private Hosp, Gallipoli Med Res Ctr, Brisbane, Qld, Australia Hosp Val dHebron, Barcelona, Spain Ist Sci San Raffaele, Emerging Bacterial Pathogens Unit, I-20132 Milan, Italy Natl Jewish Hlth, Adv Diagnost Labs, Dept Mycobacteriol, Denver, CO USA Univ Calgary, Prov Lab Publ Hlth, Calgary, AB, Canada Natl Inst Hlth & Welf, Epidemiol Surveillance & Response Unit, Dept Infect Dis Surveillance & Control, Helsinki, Finland Med Univ Warsaw, Dept Internal Med Pneumol & Allergol, Warsaw, Poland Oregon Hlth & Sci Univ, Div Infect Dis Publ Hlth & Prevent Med, Portland, OR 97201 USA Univ Freiburg, Dept Internal Med Infect Dis 2, D-79106 Freiburg, Germany Universidade Federal de São Paulo, Escola Paulista Med, Dept Microbiol Imunol & Parasitol, Disciplina Microbiol, São Paulo, Brazil German Federal Ministry of Education and Research: BMBF 01 EO 0803 Web of Science
- Published
- 2013
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