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10 results on '"Christelle Mansuy"'

1. Three-Electrode Analytical and Preparative Electrochemistry in Micro-Volume Hanging Droplets

Author

Christelle Mansuy, Olivier Buriez, Manon Guille-Collignon, Lylian Challier, Eric Labbé, Christian Amatore, Solange Lavielle, Frédéric Lemaître, Ana Isabel Perez Jimenez, Margherita Di Pisa, Processus d'Activation Sélective par Transfert d'Energie Uni-électronique ou Radiatif (UMR 8640) (PASTEUR), Université Pierre et Marie Curie - Paris 6 (UPMC)-Département de Chimie - ENS Paris, École normale supérieure - Paris (ENS-PSL), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-École normale supérieure - Paris (ENS-PSL), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Université Pierre et Marie Curie - Paris 6 (UPMC), École normale supérieure - Paris (ENS Paris), and Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-École normale supérieure - Paris (ENS Paris)

Subjects
010504 meteorology & atmospheric sciences, Chemistry, Capillary action, Electroanalysis, Analytical chemistry, Platinization, 02 engineering and technology, 021001 nanoscience & nanotechnology, Electrochemistry, Cell-penetrating peptide, 01 natural sciences, Reference electrode, lcsh:Chemistry, Droplet, lcsh:Industrial electrochemistry, lcsh:QD1-999, Volume (thermodynamics), Electrode, Fritted glass, Micro-volume, [CHIM]Chemical Sciences, 0210 nano-technology, lcsh:TP250-261, 0105 earth and related environmental sciences
Abstract

Three-electrode micro-cells equipped with a conventional reference electrode (SCE) were easily constructed based on micro-volume droplets suspended by capillary forces to the fritted glass of the SCE bridge. Working and counter electrodes were simply inserted through the droplet surface, allowing classical electrochemistry to be readily performed in minute samples. Keywords: Electroanalysis, Micro-volume, Droplet, Platinization, Cell-penetrating peptide

Published
2015

2. The Efficacies of Cell-Penetrating Peptides in Accumulating in Large Unilamellar Vesicles Depend on their Ability To Form Inverted Micelles

Author

Jean-Marie Swiecicki, Christelle Mansuy, Fabienne Burlina, Benjamin Heller, Julien Tailhades, Gérard Chassaing, Solange Lavielle, Annika Bartsch, Margherita Di Pisa, Université Pierre et Marie Curie - Paris 6 (UPMC), Institut des Biomolécules Max Mousseron [Pôle Chimie Balard] (IBMM), Ecole Nationale Supérieure de Chimie de Montpellier (ENSCM)-Institut de Chimie du CNRS (INC)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Laboratoire des Matériaux Inorganiques (LMI), Université Blaise Pascal - Clermont-Ferrand 2 (UBP)-Clermont Université-SIGMA Clermont (SIGMA Clermont)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), and Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC)-Université de Montpellier (UM)-Ecole Nationale Supérieure de Chimie de Montpellier (ENSCM)

Subjects
Lipid Bilayers, Cell, Phospholipid, Chromosomal translocation, Peptide, Cell-Penetrating Peptides, Biochemistry, Micelle, 03 medical and health sciences, chemistry.chemical_compound, medicine, Molecular Biology, Micelles, Phospholipids, Unilamellar Liposomes, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, [CHIM.ORGA]Chemical Sciences/Organic chemistry, Vesicle, Bilayer, 030302 biochemistry & molecular biology, Organic Chemistry, Phosphatidylglycerols, medicine.anatomical_structure, chemistry, Molecular Medicine, lipids (amino acids, peptides, and proteins)
Abstract

International audience; : In this study, the direct translocation of cell-penetrating peptides (CPPs) into large unilamellar vesicles (LUVs) was shown to be rapid for all the most commonly used CPPs. This translocation led within a few minutes to intravesicular accumulation up to 0.5 mM, with no need for a transbilayer potential. The accumulation of CPPs inside LUVs was found to depend on CPP sequence, CPP extravesicular concentration and phospholipid (PL) composition, either in binary or ternary mixtures of PLs. More interestingly, the role of anionic phospholipid flip-flopping in the translocation process was ascertained. CPPs enhanced the flipping of PLs, and the intravesicular CPP accumulation directly correlated with the amount of anionic PLs that had been transferred from the external to the internal leaflet of the LUV bilayer, thus demonstrating the transport of peptide/lipid complexes as inverted micelles.

Published
2014

3. Peptide-coated nanoparticles: Adsorption and desorption studies of cationic peptides on nanodiamonds

Author

Solange Lavielle, Christelle Mansuy, Gérard Chassaing, Jean-Marie Swiecicki, Julien Tailhades, Elise Lepeltier, Université Pierre et Marie Curie - Paris 6 (UPMC), Institut des Biomolécules Max Mousseron [Pôle Chimie Balard] (IBMM), Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC)-Université de Montpellier (UM)-Ecole Nationale Supérieure de Chimie de Montpellier (ENSCM), Physico-chimie, pharmacotechnie, biopharmacie (PCPB), Université Paris-Sud - Paris 11 (UP11)-Centre National de la Recherche Scientifique (CNRS), European Commission: project ``Nano4Drugs' [LSFC-CT-2005-019102], Ecole Nationale Supérieure de Chimie de Montpellier (ENSCM)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), and Ecole Nationale Supérieure de Chimie de Montpellier (ENSCM)-Institut de Chimie du CNRS (INC)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)

Subjects
[SDV]Life Sciences [q-bio], Nanoparticle, Peptide, 02 engineering and technology, 010402 general chemistry, 01 natural sciences, Nanodiamonds, Colloid and Surface Chemistry, Adsorption, Physisorption, Quantification, Zeta potential, Organic chemistry, [CHIM]Chemical Sciences, Functionalization, chemistry.chemical_classification, Cationic polymerization, Adsorption/desorption, 021001 nanoscience & nanotechnology, Combinatorial chemistry, 0104 chemical sciences, Matrix-assisted laser desorption/ionization, chemistry, Surface modification, Nanoparticles, 0210 nano-technology, Peptides
Abstract

International audience; The functionalization of nanoparticle surfaces remains a major challenge for broader applications in biology. To study the physisorption of peptides on nanodiamonds (NDs), we developed reliable and facile methods: UV titration, MALDI-TOF mass spectrometry or fluorescence spectrophotometry. These readily applicable procedures allowed us to analyze the adsorption and desorption behaviors of different cationic peptides. A rough estimate led to propose that an average of three to four shells of amphiphilic peptides rapidly adsorbed on NDs surface: about half of the molecules being adsorbed with a high affinity, while the other half may be exchanged within a few minutes. If a photoactivatable amino acid was incorporated in the peptide sequence, the subsequent irradiation allowed similarly the coating of three to five shells of peptides on the NDs surface, but in that case peptides were not exchangeable at all, even after a few days. Stable cationic nanodiamonds may be obtained by simple physisorption of amphiphilic peptides, leading to nanoparticles with a positive zeta potential in the appropriate range for biological applications.

Published
2013

4. Electrochemistry of a ferrocene-grafted cell-penetrating peptide

Author

Gérard Chassaing, Eric Labbé, Olivier Buriez, Pierluca Messina, Christelle Mansuy, Marie Béranger, Christian Amatore, Solange Lavielle, Géraldine Hallais, Université Pierre et Marie Curie - Paris 6 (UPMC), Processus d'Activation Sélective par Transfert d'Energie Uni-électronique ou Radiatif (UMR 8640) (PASTEUR), Université Pierre et Marie Curie - Paris 6 (UPMC)-Département de Chimie - ENS Paris, École normale supérieure - Paris (ENS-PSL), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-École normale supérieure - Paris (ENS-PSL), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), École normale supérieure - Paris (ENS Paris), and Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-École normale supérieure - Paris (ENS Paris)

Subjects
biology, 010405 organic chemistry, [CHIM.ORGA]Chemical Sciences/Organic chemistry, General Chemical Engineering, Cationic polymerization, Analytical chemistry, 010402 general chemistry, Electrochemistry, Photochemistry, 01 natural sciences, 0104 chemical sciences, chemistry.chemical_compound, Ferrocene, chemistry, Monolayer, Electrode, biology.protein, Moiety, Voltammetry, ComputingMilieux_MISCELLANEOUS, Avidin
Abstract

A cationic cell-penetrating peptide (CPP) labeled with both a ferrocenyl (Fc) moiety and a biotin (B) was successfully synthesized and investigated by electrochemistry. This original CPP derivative noted as Fc-CPP-B could be electrochemically detected, at a micromolar concentration, at a naked gold bead electrode. The presence of a biotin tag in the Fc-CPP-B complex allowed its complexation with avidin, which was itself tethered to a thiolated self-assembled monolayer. Such an avidin-modified gold surface, characterized by atomic force microscopy (AFM), allowed the immobilization of Fc-CPP-B onto the electrode surface, which greatly enhanced its electrochemical detection. Nevertheless, under these conditions the electrogenerated ferrocenium cation could not be reduced during the backward scan, indicating its unexpected reactivity when tethered within the avidin environment. In terms of detection and redox probe regeneration the best results were obtained at a glassy carbon electrode modified with a cation-exchange polymer. Ion-exchange voltammetry, performed under these conditions, allowed the pre-concentration of the peptide at the electrode surface thanks to the net positive charge of the CPP derivative. Interestingly, the anionic character of the polymer contributed to retain the electrogenerated cation Fc + in the film so that it could be reduced back to its original neutral form during the reverse voltammetric scans.

Published
2012

5. Nanodiamond as a Vector for siRNA Delivery to Ewing Sarcoma Cells

Author

Claude Malvy, Jean-Rémi Bertrand, Christelle Mansuy, François Treussart, Jacques Botsoa, Solange Lavielle, Thierry Gacoin, Marie-Pierre Adam, Anna Alhaddad, Géraldine Dantelle, Sandrine Perruchas, Laboratoire de physique de la matière condensée (LPMC), École polytechnique (X)-Centre National de la Recherche Scientifique (CNRS), Laboratoire des Matériaux Inorganiques (LMI), Université Blaise Pascal - Clermont-Ferrand 2 (UBP)-Clermont Université-SIGMA Clermont (SIGMA Clermont)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Université Pierre et Marie Curie - Paris 6 (UPMC), Vectorologie et transfert de gènes (VTG / UMR8121), Université Paris-Sud - Paris 11 (UP11)-Institut Gustave Roussy (IGR)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Photonique Quantique et Moléculaire (LPQM), École normale supérieure - Cachan (ENS Cachan)-CentraleSupélec-Centre National de la Recherche Scientifique (CNRS), Université Paris-Sud - Paris 11 (UP11), Université Blaise Pascal - Clermont-Ferrand 2 (UBP)-Clermont Université-Sigma CLERMONT (Sigma CLERMONT)-Centre National de la Recherche Scientifique (CNRS), and Centre National de la Recherche Scientifique (CNRS)-CentraleSupélec-École normale supérieure - Cachan (ENS Cachan)

Subjects
Small interfering RNA, Materials science, media_common.quotation_subject, Cell, FOS: Physical sciences, Nanoparticle, Bone Neoplasms, Sarcoma, Ewing, 02 engineering and technology, Transfection, 010402 general chemistry, 01 natural sciences, Nanodiamonds, Biomaterials, Mice, Cell Line, Tumor, Gene expression, medicine, Animals, General Materials Science, Physics - Biological Physics, RNA, Small Interfering, Nanodiamond, Internalization, media_common, Messenger RNA, [CHIM.ORGA]Chemical Sciences/Organic chemistry, Biomolecules (q-bio.BM), General Chemistry, 021001 nanoscience & nanotechnology, Physics - Medical Physics, Xenograft Model Antitumor Assays, Molecular biology, 0104 chemical sciences, medicine.anatomical_structure, Quantitative Biology - Biomolecules, Microscopy, Fluorescence, Biological Physics (physics.bio-ph), FOS: Biological sciences, Drug delivery, NIH 3T3 Cells, Biophysics, Medical Physics (physics.med-ph), 0210 nano-technology, Biotechnology
Abstract

International audience; The ability of diamond nanoparticles (nanodiamonds, NDs) to deliver small interfering RNA (siRNA) into Ewing sarcoma cells is investigated with a view to the possibility of in-vivo anticancer nucleic-acid drug delivery. siRNA is adsorbed onto NDs that are coated with cationic polymer. Cell uptake of NDs is demonstrated by taking advantage of the NDs' intrinsic fluorescence from embedded color-center defects. Cell toxicity of these coated NDs is shown to be low. Consistent with the internalization efficacy, a specific inhibition of EWS/Fli-1 gene expression is shown at the mRNA and protein level by the ND-vectorized siRNA in a serum-containing medium.

Published
2011

6. Peptide-grafted nanodiamonds: preparation, cytotoxicity and uptake in cells

Author

Christelle Mansuy, Solange Lavielle, Gérard Chassaing, Fabienne Burlina, Jean-Paul Boudou, Theano Irinopoulou, Sandrine Sagan, Stephanie Vial, Laboratoire des Matériaux Inorganiques (LMI), Université Blaise Pascal - Clermont-Ferrand 2 (UBP)-Clermont Université-Sigma CLERMONT (Sigma CLERMONT)-Centre National de la Recherche Scientifique (CNRS), Université Pierre et Marie Curie - Paris 6 (UPMC), Institut du Fer à Moulin, Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de la Santé et de la Recherche Médicale (INSERM), Biogéochimie et écologie des milieux continentaux (Bioemco), Centre National de la Recherche Scientifique (CNRS)-AgroParisTech-Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de la Recherche Agronomique (INRA)-École normale supérieure - Paris (ENS Paris), Université Blaise Pascal - Clermont-Ferrand 2 (UBP)-Clermont Université-SIGMA Clermont (SIGMA Clermont)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), École normale supérieure - Paris (ENS-PSL), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut de Recherche pour le Développement (IRD)-Institut National de la Recherche Agronomique (INRA)-Université Pierre et Marie Curie - Paris 6 (UPMC)-AgroParisTech-Centre National de la Recherche Scientifique (CNRS), École normale supérieure - Paris (ENS Paris), and Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut National de la Recherche Agronomique (INRA)-Université Pierre et Marie Curie - Paris 6 (UPMC)-AgroParisTech-Centre National de la Recherche Scientifique (CNRS)

Subjects
Confocal, Cells, Intracellular Space, Peptide, 02 engineering and technology, CHO Cells, 010402 general chemistry, 01 natural sciences, Biochemistry, Cricetulus, Cricetinae, Fluorescence microscope, Organic chemistry, Animals, Cytotoxicity, Molecular Biology, chemistry.chemical_classification, Cell Death, Chemistry, [CHIM.ORGA]Chemical Sciences/Organic chemistry, Organic Chemistry, 021001 nanoscience & nanotechnology, Fluorescence, Polyelectrolyte, 0104 chemical sciences, Surface coating, Silanization, Biophysics, Molecular Medicine, Nanoparticles, Diamond, 0210 nano-technology, Oxidoreductases, Oligopeptides
Abstract

International audience; Nanodiamonds that were prepared by high pressure/high temperature were functionalized with biomolecules for biological applications. Nanodiamonds (NDs, < or =35 nm) that were coated by silanization or with polyelectrolyte layers were grafted with a fluorescent thiolated peptide via a maleimido function; this led to an aqueous colloidal suspension that was stable for months. These substituted NDs were not cytotoxic for CHO cells. Their capacity to enter mammalian cells, and their localisation inside were ascertained after labelling the nucleus and actin, by examining the cells by confocal, reflected light and fluorescence microscopy.

Published
2008

7. Surface characterization of sol-gel derived scintillating rare-earth doped Lu2SiO5 thin films

Author

Jean-Marie Nedelec, Rachid Mahiou, Jean Grimblot, Christelle Mansuy, Eric Tomasella, Laboratoire des Matériaux Inorganiques (LMI), Université Blaise Pascal - Clermont-Ferrand 2 (UBP)-Clermont Université-SIGMA Clermont (SIGMA Clermont)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Unité de Catalyse et Chimie du Solide - UMR 8181 (UCCS), Université d'Artois (UA)-Centrale Lille-Institut de Chimie du CNRS (INC)-Université de Lille-Centre National de la Recherche Scientifique (CNRS), LuNATIC N5501, and Centrale Lille Institut (CLIL)-Université d'Artois (UA)-Centrale Lille-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC)-Université de Lille

Subjects
History, Materials science, Analytical chemistry, 02 engineering and technology, scintillators, coatings, 010402 general chemistry, 01 natural sciences, Education, law.invention, X-ray photoelectron spectroscopy, law, sol-gel, Thin film, Crystallization, Sol-gel, Spin coating, Doping, [CHIM.MATE]Chemical Sciences/Material chemistry, 021001 nanoscience & nanotechnology, 0104 chemical sciences, Computer Science Applications, Carbon film, Amorphous carbon, thin films, 0210 nano-technology
Abstract

International audience; Rare earth doped Lu2SiO5 thin films have been prepared by combining sol-gel process and spin coating. Annealing treatment results in the crystallization of the film and efficient incorporation of rare earth doping ions. XPS and RBS spectrocopies showed that the composition of the films is close to the nominal one. Adventitious carbon has been observed and attributed to incomplete pyrolysis of metal-organic precursors. XPS concentrations profiles show a good homogeneity for the films. RBS demonstrated some inter-diffusion between amorphous carbon substrate and silicate films resulting in a gradient of carbon at the interface between the substrate and the film itself.

Published
2008

8. Concentration effect on the scintillation properties of Sol-Gel derived LuBO3 doped with Eu3+ and Tb3+

Author

Christophe Dujardin, Jean-Marie Nedelec, Rachid Mahiou, Christelle Mansuy, Laboratoire des Matériaux Inorganiques (LMI), Université Blaise Pascal - Clermont-Ferrand 2 (UBP)-Clermont Université-SIGMA Clermont (SIGMA Clermont)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Physico-Chimie des Matériaux Luminescents (LPCML), Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon, LuminiX RNTS 01-B262, Laboratoire des Matériaux Inorganiques ( LMI ), Université Blaise Pascal - Clermont-Ferrand 2 ( UBP ) -Clermont Université-Sigma CLERMONT ( Sigma CLERMONT ) -Centre National de la Recherche Scientifique ( CNRS ), Laboratoire de Physico-Chimie des Matériaux Luminescents ( LPCML ), Université Claude Bernard Lyon 1 ( UCBL ), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique ( CNRS ), LuminiX RNTS, LuNaTIC ACI Nanostructures, Université Claude Bernard Lyon 1 (UCBL), and Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS)

Subjects
Scanning electron microscope, Analytical chemistry, medical imaging, chemistry.chemical_element, Concentration effect, PACS 78.55.Hx, 81.20. Fw, 29.40.Mc, 73.61.Tm, 02 engineering and technology, scintillators, Scintillator, 010402 general chemistry, 01 natural sciences, x-ray conversion, Inorganic Chemistry, borate, sol-gel, Electrical and Electronic Engineering, Physical and Theoretical Chemistry, Boron, Spectroscopy, Sol-gel, Scintillation, Organic Chemistry, Doping, PACS: 78.55.Hx, 81.20. Fw, 29.40.Mc, 73.61.Tm, [CHIM.MATE]Chemical Sciences/Material chemistry, 021001 nanoscience & nanotechnology, Atomic and Molecular Physics, and Optics, 0104 chemical sciences, Electronic, Optical and Magnetic Materials, chemistry, [ CHIM.MATE ] Chemical Sciences/Material chemistry, 0210 nano-technology, Nuclear chemistry, Solid solution
Abstract

International audience; Lu1-xEuxBO3 and Lu1-xTbxBO3 powders have been prepared by a sol-gel process with 0 < x < 0.15 for Eu3+ and 0 < x < 0.05 for Tb3+. The purity of powders has been verified by X-Ray diffraction and the results confirm that all the materials have the vaterite type even if the calcination has been performed at 800°C. Furthermore, the solid solution for LuBO3 vaterite is observed up to x=0.15 and x=0.05 for europium and terbium ions respectively. So doping with Eu3+ or Tb3+ ions does not affect the structure. These materials have also been analyzed by Fourier Transform Infra Red Spectroscopy. The morphology of the powders has been studied by Scanning Electron Microscopy and shows a very nice morphology with small spherical particles with narrow size distribution. Optical properties have then been studied to confirm the effective substitution of Eu3+ or Tb3+ for Lu3+ ions and to determine the materials scintillation performances. The optima, in term of scintillation yield, are obtained for Eu3+ and Tb3+ concentration of x=0.05 in both cases. The afterglows have also been measured and confirm the potentiality of these materials as scintillators.

Published
2007

9. Scintillation of Sol-Gel derived Lutetium orthophosphate doped with rare earth ions

Author

Christophe Dujardin, Jean-Marie Nedelec, Rachid Mahiou, Christelle Mansuy, Laboratoire des Matériaux Inorganiques (LMI), Université Blaise Pascal - Clermont-Ferrand 2 (UBP)-Clermont Université-SIGMA Clermont (SIGMA Clermont)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Physico-Chimie des Matériaux Luminescents (LPCML), Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon, LuminiX RNTS LuNaTIC ACI nanostructures, Laboratoire des Matériaux Inorganiques ( LMI ), Université Blaise Pascal - Clermont-Ferrand 2 ( UBP ) -Clermont Université-Sigma CLERMONT ( Sigma CLERMONT ) -Centre National de la Recherche Scientifique ( CNRS ), Laboratoire de Physico-Chimie des Matériaux Luminescents ( LPCML ), Université Claude Bernard Lyon 1 ( UCBL ), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique ( CNRS ), Université Claude Bernard Lyon 1 (UCBL), and Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS)

Subjects
Thermogravimetric analysis, Materials science, rare earth, Analytical chemistry, chemistry.chemical_element, 02 engineering and technology, scintillators, Scintillator, 010402 general chemistry, 01 natural sciences, Biomaterials, Materials Chemistry, luminescence, Sol-gel, phosphate, Scintillation, General Chemistry, [CHIM.MATE]Chemical Sciences/Material chemistry, 021001 nanoscience & nanotechnology, Condensed Matter Physics, Lutetium, 0104 chemical sciences, Electronic, Optical and Magnetic Materials, Characterization (materials science), Amorphous solid, chemistry, [ CHIM.MATE ] Chemical Sciences/Material chemistry, Ceramics and Composites, 0210 nano-technology, Luminescence
Abstract

In this paper, the synthesis, the characterization and the scintillation properties of LuPO4 doped, with several concentrations of Ce3+, Eu3+ and Tb3+ ions, are presented. These materials have been synthesized by sol-gel process. The purity of powders has been verified by X-Ray diffraction and the results confirm the xenotime structure of all the materials. A thermogravimetric analysis allows the obtention of informations on the crystallisation of LuPO4 and the study of its evolution from the amorphous to crystalline form. The morphology of the powders has been studied by Scanning Electron Microscopy and shows that the powders are constituted of small particles with narrow size distribution. Optical properties have been studied in order to determine the scintillation performances of these materials. The optima are obtained for Ce3+, Eu3+ and Tb3+ concentration of respectively 0.1%, 10% and 5% with high scintillation yields. This study thus confirms the potentialities of these materials as scintillators.

Published
2006

10. Characterization of sol-gel derived scintillating LuBO3 films doped with rare earth ions

Author

Christelle Mansuy, Eric Tomasella, Jean Grimblot, Jean-Marie Nedelec, Rachid Mahiou, Léon Gengembre, Unité de Catalyse et Chimie du Solide - UMR 8181 (UCCS), Centrale Lille Institut (CLIL)-Université d'Artois (UA)-Ecole Centrale de Lille-Centre National de la Recherche Scientifique (CNRS)-Université de Lille, Laboratoire des Matériaux Inorganiques (LMI), Université Blaise Pascal - Clermont-Ferrand 2 (UBP)-Clermont Université-SIGMA Clermont (SIGMA Clermont)-Centre National de la Recherche Scientifique (CNRS), Université de Lille-Centre National de la Recherche Scientifique (CNRS)-Ecole Centrale de Lille-Université d'Artois (UA)-Centrale Lille Institut (CLIL), Université Blaise Pascal - Clermont-Ferrand 2 (UBP)-Clermont Université-SIGMA Clermont (SIGMA Clermont)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de catalyse de Lille - UMR 8010 (LCL), Université de Lille, Sciences et Technologies-Centrale Lille-Centre National de la Recherche Scientifique (CNRS), and LuminiX RNTS LuNaTIC ACI NAnostructures

Subjects
Materials science, Mineralogy, 02 engineering and technology, scintillators, engineering.material, 010402 general chemistry, 01 natural sciences, law.invention, Coating, X-ray photoelectron spectroscopy, law, Materials Chemistry, luminescence, sol-gel, Thin film, Crystallization, Sol-gel, Spin coating, Metals and Alloys, Surfaces and Interfaces, [CHIM.MATE]Chemical Sciences/Material chemistry, 021001 nanoscience & nanotechnology, 0104 chemical sciences, Surfaces, Coatings and Films, Electronic, Optical and Magnetic Materials, PACS: 78.55.Hx, 81.15.Rs, 81.20. Fw, Carbon film, Chemical engineering, Amorphous carbon, engineering, xps, rare earth ions, 0210 nano-technology, rbs
Abstract

Rare earth doped LuBO 3 thin films have been prepared by combining sol-gel process and coating techniques such as spin coating and spray pyrolysis. Annealing treatment results in the crystallization of the film as vaterite phase and incorporation of the doping ions in solid solution. XPS and RBS spectroscopies showed that the composition of the films is close to the nominal one. Adventitious carbon has been observed and attributed to incomplete pyrolysis of metal-organic precursors. XPS concentration profiles show a good homogeneity for the films. RBS demonstrated some inter-diffusion between amorphous carbon substrate and borate films resulting in a gradient of carbon at the interface between the substrate and the film itself. Finally scintillation spectra have been recorded and demonstrate the potentiality of these films to be used as X-ray intensifying screens.

Published
2006

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