1. Factors associated with anaemia among preschool- age children in underprivileged neighbourhoods in Antananarivo, Madagascar
- Author
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Mirella Malala Randrianarisoa, Maheninasy Rakotondrainipiana, Ravaka Randriamparany, Prisca Vega Andriantsalama, Anjasoa Randrianarijaona, Azimdine Habib, Annick Robinson, Lisette Raharimalala, Francis Allen Hunald, Aurélie Etienne, Jean-Marc Collard, Frédérique Randrianirina, Robert Barouki, Clement Pontoizeau, Alison Nestoret, Nathalie Kapel, Philippe Sansonetti, Pascale Vonaesch, Rindra Vatosoa Randremanana, Unité d’Épidémiologie et de Recherche clinique [Antananarivo, Madagascar], Institut Pasteur de Madagascar, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP), Unité de Bactériologie Expérimentale [Antananarivo, Madagascar] (IPM), Centre Hospitalier Universitaire Mère-Enfant de Tsaralalàna (CHUMET), Centre Hospitalier Universitaire Joseph Ravoahangy Andrianavalona (CHUJRA), Institut Pasteur de Shanghai, Académie des Sciences de Chine - Chinese Academy of Sciences (IPS-CAS), Réseau International des Instituts Pasteur (RIIP), CHU Necker - Enfants Malades [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Pathogénie microbienne moléculaire, Institut Pasteur [Paris] (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM), Université de Lausanne = University of Lausanne (UNIL), This study was supported by the Total Corporate Foundation, the Institut Pasteur, the Fondation Odyssey Re and the Fondation Petram. P.V. was supported by an Early and Advanced Postdoctoral Fellowship as well by as a Return Fellowship from the Swiss National Science Foundation, a Roux-Cantarini Postdoctoral Fellowship and L’Oréal-UNESCO for Women in Science Fellowship., and Collard, Jean-Marc
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Adolescent ,Anemia, Iron-Deficiency ,[SDV]Life Sciences [q-bio] ,Public Health, Environmental and Occupational Health ,Anemia ,Anaemia ,Iron Deficiencies ,Factors ,Underprivileged neighbourhoods ,[SDV] Life Sciences [q-bio] ,Child, Preschool ,Ferritins ,Madagascar ,Prevalence ,Humans ,Child ,Poverty ,Children ,Antananarivo - Abstract
BackgroundAnaemia occurs in children when the haemoglobin level in the blood is less than the normal (11 g/dL), the consequence is the decrease of oxygen quantity in the tissues. It is a prevalent public health problem in many low-income countries, including Madagascar, and data on risk factors are lacking. We used existing data collected within the pathophysiology of environmental enteric dysfunction (EED) in Madagascar and the Central African Republic project (AFRIBIOTA project) conducted in underprivileged neighbourhoods of Antananarivo to investigate the factors associated with anaemia in children 24 to 59 months of age.MethodsChildren included in the AFRIBIOTA project in Antananarivo for whom data on haemoglobin and ferritin concentrations were available were included in the study. Logistic regression modelling was performed to identify factors associated with anaemia.ResultsOf the 414 children included in this data analysis, 24.4% were found to suffer from anaemia. We found that older children (adjusted OR: 0.95; 95% CI: 0.93–0.98) were less likely to have anaemia. Those with iron deficiency (adjusted OR: 6.1; 95% CI: 3.4–11.1) and those with a high level of faecal calprotectin (adjusted OR: 2.5; 95% CI: 1.4–4.4) were more likely to have anaemia than controls.ConclusionsTo reduce anaemia in the children in this underprivileged area, more emphasis should be given to national strategies that improve children’s dietary quality and micronutrient intake. Furthermore, existing measures should be broadened to include measures to reduce infectious disease burden.
- Published
- 2022