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3 results on '"Anna E Goudriaan"'

1. Sodium oxybate for the maintenance of abstinence in alcohol-dependent patients: An international, multicenter, randomized, double-blind, placebo-controlled trial

Author

Julien Guiraud, Giovanni Addolorato, Mariangela Antonelli, Henri-Jean Aubin, Andrea de Bejczy, Amine Benyamina, Roberto Cacciaglia, Fabio Caputo, Maurice Dematteis, Anna Ferrulli, Anna E Goudriaan, Antoni Gual, Otto-Michael Lesch, Icro Maremmani, Antonio Mirijello, David J Nutt, François Paille, Pascal Perney, Roch Poulnais, Quentin Raffaillac, Jürgen Rehm, Benjamin Rolland, Claudia Rotondo, Bruno Scherrer, Nicolas Simon, Katrin Skala, Bo Söderpalm, Lorenzo Somaini, Wolfgang H Sommer, Rainer Spanagel, Gabriele A Vassallo, Henriette Walter, Wim van den Brink, Amsterdam UMC - Amsterdam University Medical Center, University of Amsterdam [Amsterdam] (UvA), Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Centre de recherche en épidémiologie et santé des populations (CESP), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Paul Brousse-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Saclay, Hôpital Paul Brousse, University of Gothenburg (GU), Laboratorio Farmaceutico CT [San Remo, Italy] (LFCT), Università degli Studi di Ferrara = University of Ferrara (UniFE), Université Grenoble Alpes (UGA), IRCCS Ospedale San Raffaele [Milan, Italy], Università degli Studi di Milano = University of Milan (UNIMI), Amsterdam School of Public Health [the Netherlands], Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Universitat de Barcelona (UB), University of Vienna [Vienna], University of Pisa - Università di Pisa, Istituto di Ricovero e Cura a Carattere Scientifico, Ospedale Casa Sollievo della Sofferenza [San Giovanni Rotondo] (IRCCS), Imperial College London, Centre Hospitalier Universitaire de Nancy (CHU Nancy), Centre Hospitalier Universitaire de Nîmes (CHU Nîmes), Université de Montpellier (UM), D&A Pharma Paris - Laboratoires pharmaceutiques (DAPP), Centre for Addiction and Mental Health [Toronto] (CAMH), University of Toronto, Technische Universität Dresden = Dresden University of Technology (TU Dresden), I.M. Sechenov First Moscow State Medical University [Moscow, Russia] (MSMU), Centre de recherche en neurosciences de Lyon - Lyon Neuroscience Research Center (CRNL), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Université Jean Monnet - Saint-Étienne (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Centro di Riferimento Alcologico della Regione Lazio [Roma, Italy] (CRARL), Bruno Scherrer Conseil [Saint Arnoult en Yvelines] (BSC), Sciences Economiques et Sociales de la Santé & Traitement de l'Information Médicale (SESSTIM - U1252 INSERM - Aix Marseille Univ - UMR 259 IRD), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM), Service de Pharmacologie Clinique [AP-HM Hôpital Ste Marguerite], Hôpital Sainte-Marguerite [CHU - APHM] (Hôpitaux Sud ), Medizinische Universität Wien = Medical University of Vienna, Addiction Treatment Center [ASL Biella, Italy] (ATC - Local Health Unit), Universität Heidelberg [Heidelberg] = Heidelberg University, Barone Lombardo Hospital [Canicattì, Italy] (BLH), Amsterdam University Medical Centers (Amsterdam UMC), Adult Psychiatry, APH - Mental Health, Amsterdam Neuroscience - Compulsivity, Impulsivity & Attention, and APH - Digital Health

Subjects
Adult, Male, MESH: Ethanol, Alcohol Drinking, Alcohol use disorders, Double-Blind Method, MESH: Alcoholism, Humans, Maintenance of abstinence, Pharmacology (medical), MESH: Double-Blind Method, MESH: Treatment Outcome, Pharmacology, MESH: Humans, Ethanol, Sodium oxybate, Alcohol dependence, MESH: Adult, MESH: Male, Psychiatry and Mental health, Alcoholism, Treatment Outcome, [SDV.MHEP.PSM]Life Sciences [q-bio]/Human health and pathology/Psychiatrics and mental health, [SDV.SP.PHARMA]Life Sciences [q-bio]/Pharmaceutical sciences/Pharmacology, Female, [SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC], MESH: Sodium Oxybate, GHB, MESH: Female, RCT, MESH: Alcohol Drinking
Abstract

Background: Sodium oxybate (SMO) has been shown to be effective in the maintenance of abstinence (MoA) in alcohol-dependent patients in a series of small randomized controlled trials (RCTs). These results needed to be confirmed by a large trial investigating the treatment effect and its sustainability after medication discontinuation. Aims: To confirm the SMO effect on (sustained) MoA in detoxified alcohol-dependent patients. Methods: Large double-blind, randomized, placebo-controlled trial in detoxified adult alcohol-dependent outpatients (80% men) from 11 sites in four European countries. Patients were randomized to 6 months SMO (3.3–3.9 g/day) or placebo followed by a 6-month medication-free period. Primary outcome was the cumulative abstinence duration (CAD) during the 6-month treatment period defined as the number of days with no alcohol use. Secondary outcomes included CAD during the 12-month study period. Results: Of the 314 alcohol-dependent patients randomized, 154 received SMO and 160 received placebo. Based on the pre-specified fixed-effect two-way analysis of variance including the treatment-by-site interaction, SMO showed efficacy in CAD during the 6-month treatment period: mean difference +43.1 days, 95% confidence interval (17.6–68.5; p = 0.001). Since significant heterogeneity of effect across sites and unequal sample sizes among sites ( n = 3–66) were identified, a site-level random meta-analysis was performed with results supporting the pre-specified analysis: mean difference +32.4 days, p = 0.014. The SMO effect was sustained during the medication-free follow-up period. SMO was well-tolerated. Conclusions: Results of this large RCT in alcohol-dependent patients demonstrated a significant and clinically relevant sustained effect of SMO on CAD. Trial registration: ClinicalTrials.gov Identifier: NCT04648423

Published
2022
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2. Transcranial Electrical and Magnetic Stimulation (tES and TMS) for Addiction Medicine: A Consensus Paper on the Present State of the Science and the Road Ahead

Author

Colleen A. Hanlon, Anne Sauvaget, Alireza Shahbabaie, Pinhas Pn Dannon, Yoon Hee Cha, Marie Grall-Bronnec, Haley Rafferty, Graziella Madeo, Mohammad-Reza Zarrindast, Eman M. Khedr, Renée S. Schluter, Katie Witkiewitz, Fatemeh Yavari, Laurie Zawertailo, Marom Bikson, Xiaochu Zhang, Michael Mj Wesley, William Wm McDonald, Eric D. Claus, Giovanni Addolorato, Christos Kouimtsidis, Nastaran Malmir, Sarah Herremans, Josanne D. M. van Dongen, Anna E. Goudriaan, Paul B. Fitzgerald, Antonello Bonci, William Wv Lechner, Antonio Verdejo-García, Mohammad Nasehi, Abraham Zangen, Gaëlle Challet-Bouju, Tess E. den Uyl, Karolina Kozak, Primavera Pa Spagnolo, Ilse Verveer, Evgeny Krupitsky, Asif Jamil, Chris Baeken, Hamed Ekhtiari, Claus Lamm, Salvatore Campanella, Betty Jo Salmeron, Luigi Gallimberti, Mauro Pettorruso, Luis Castelo-Branco, Martin P. Paulus, Flavio Fröhlich, Ti-Fei Yuan, Elliot A. Stein, Chiara Montemitro, Martin J Herrmann, Justine W. Welsh, Carmen S. Sergiou, John R. Fedota, Marco Diana, Alessandra Del Felice, Stacey Sb Daughters, Vincent Van Waes, Xavier Noël, Basant Pradhan, Masoud Nosratabadi, Ester Em Nakamura-Palacios, Massimo Di Giannantonio, Hosna Tavakoli, Vincent Vp Clark, Gregory L. Sahlem, Ganesan Venkatasubramanian, Christine E. Sheffer, Tony P. George, Vaughn Vr Steele, Michael A. Nitsche, Felipe Fregni, Shirley Fecteau, Samir Sk Praharaj, Giovanni Martinotti, MethodS in Patients-centered outcomes and HEalth ResEarch (SPHERE), Université de Tours-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Nantes - UFR des Sciences Pharmaceutiques et Biologiques, Université de Nantes (UN)-Université de Nantes (UN), Brain, Body and Cognition, Clinical sciences, Neuroprotection & Neuromodulation, Psychiatry, Faculty of Medicine and Pharmacy, Université de Tours (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Nantes - UFR des Sciences Pharmaceutiques et Biologiques, and Clinical Psychology

Subjects
Outcome Assessment, [SDV]Life Sciences [q-bio], Review, Transcranial Direct Current Stimulation, tDCS, Behavioral Neuroscience, 0302 clinical medicine, Outcome Assessment, Health Care, rTMS, State of the science, tES, health care economics and organizations, media_common, Cognitive science, Psychiatry, NIBS, Neuromodulation (medicine), 3. Good health, Systematic review, Neuropsychology and Physiological Psychology, Practice Guidelines as Topic, Psychology, Addiction Medicine, Transcranial electrical stimulation, Substance-Related Disorders, Settore MED/12 - GASTROENTEROLOGIA, Best practice, media_common.quotation_subject, Cognitive Neuroscience, Addiction, Substance use disorder, Article, 03 medical and health sciences, Non-invasive brain stimulation, Transcranial magnetic stimulation, Humans, Mental health, 030227 psychiatry, Health Care, Addiction medicine, Brain stimulation, 030217 neurology & neurosurgery
Abstract

International audience; There is growing interest in non-invasive brain stimulation (NIBS) as a novel treatment option for substance-use disorders (SUDs). Recent momentum stems from a foundation of preclinical neuroscience demonstrating links between neural circuits and drug consuming behavior, as well as recent FDA-approval of NIBS treatments for mental health disorders that share overlapping pathology with SUDs. As with any emerging field, enthusiasm must be tempered by reason; lessons learned from the past should be prudently applied to future therapies. Here, an international ensemble of experts provides an overview of the state of transcranial-electrical (tES) and transcranial-magnetic (TMS) stimulation applied in SUDs. This consensus paper provides a systematic literature review on published data - emphasizing the heterogeneity of methods and outcome measures while suggesting strategies to help bridge knowledge gaps. The goal of this effort is to provide the community with guidelines for best practices in tES/TMS SUD research. We hope this will accelerate the speed at which the community translates basic neuroscience into advanced neuromodulation tools for clinical practice in addiction medicine.

Published
2019
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3. Association between motor timing and treatment outcomes in patients with alcohol and/or cocaine use disorder in a rehabilitation program

Author

Anna E. Goudriaan, Yvonne Delevoye-Turrell, Susanne Yvette Young, J. J. J. van Hoof, Soraya Seedat, Stellenbosch University, Sciences Cognitives et Sciences Affectives (SCALab) - UMR 9193 (SCALab), Université de Lille-Centre National de la Recherche Scientifique (CNRS), Radboud University Medical Center [Nijmegen], VU University Medical Center [Amsterdam], Laboratoire Sciences Cognitives et Sciences Affectives - UMR 9193 (SCALab), Université de Lille, CNRS, CHU Lille, University of Stellenbosch Business School [Cape Town] [USB ], Laboratoire Sciences Cognitives et Sciences Affectives - UMR 9193 [SCALab], Amsterdam Neuroscience - Compulsivity, Impulsivity & Attention, and Adult Psychiatry

Subjects
Counseling, Male, Time Factors, Poison control, Neuropsychological Tests, Study Protocol, [SCCO]Cognitive science, 0302 clinical medicine, Clinical Protocols, Attention, media_common, Substance dependence, 05 social sciences, Motor timing, Neuropsychology, Cognition, Middle Aged, humanities, Alcoholism, Psychiatry and Mental health, Memory, Short-Term, Treatment Outcome, Psychotherapy, Group, Female, medicine.symptom, Psychology, Prognostic value, Clinical psychology, Adult, Impulsivity, Adolescent, media_common.quotation_subject, Addiction, 050105 experimental psychology, Cocaine dependence, Cocaine-Related Disorders, Young Adult, 03 medical and health sciences, Patient Education as Topic, medicine, Humans, 0501 psychology and cognitive sciences, Working memory, Action planning, Theoretical frameworks for substance use dependence, medicine.disease, [SDV.MHEP.PSM]Life Sciences [q-bio]/Human health and pathology/Psychiatrics and mental health, Impulsive Behavior, Executive functioning, Psychomotor Performance, 030217 neurology & neurosurgery, Biomarkers
Abstract

BACKGROUND: Individuals with Substance Use Disorders (SUDs) have disruptions in the brain's dopaminergic (DA) system and the functioning of its target neural substrates (striatum and prefrontal cortex). These substrates are important for the normal processing of reward, inhibitory control and motivation. Cognitive deficits in attention, impulsivity and working memory have been found in individuals with SUDs and are predictors of poor SUD treatment outcomes and relapse in alcohol and cocaine dependence specifically. Furthermore, the DA system and accompanying neural substrates play a key role in the timing of motor acts (motor timing). Motor timing deficits have been found in DA system related disorders and more recently also in individuals with SUDs. Motor timing is found to correlate with attention, impulsivity and working memory deficits. To our knowledge motor timing, with regards to treatment outcome and relapse, has not been investigated in populations with SUDs. METHODS/DESIGN: This study aims to investigate motor timing and its relation to treatment response (at 8 weeks) and relapse (at 12 months) in cocaine and/or alcohol dependent individuals. The tested sensitivity values of motor timing parameters will be compared to a battery of neurocognitive tests, owing to the novelty of the motor task battery, the confounding effects of attention and working memory on motor timing paradigms, and high impulsivity levels found in individuals with SUDs. DISCUSSION: This research will contribute to current knowledge of neuropsychological deficits associated with treatment response in SUDs and possibly provide an opportunity to individualize and modify currently available treatments through the possible prognostic value of motor task performance in cocaine and/or alcohol dependent individuals. 16

Published
2016
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