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A new type of ligand-free Ni-nanoparticles supported on rGO (size distribution average d = 9 ± 3 nm) was prepared and fully characterized via morphological (Fe-SEM), structural (P-XRD, HR-TEM), and spectroscopic (ICP-EOS, XPS) analysis tools. The metal composite was effectively employed in the unprecedented heterogeneously Ni-assisted cross-coupling reaction of aryl/vinyl iodides and thiocarboxylates. A range of sulfur-containing aryl as well as vinyl derivatives (15 examples) was achieved in high yields (up to 82%), under mild reaction conditions, and with wide functional group tolerance. [ABSTRACT FROM AUTHOR]

A perspective on the literature dealing with the organocatalytic asymmetric preparation of axially chiral N-heterocycles is provided. A particular focus is devoted to rationalize the synthetic strategies employed in each case. Moreover, specific classes of organocatalysts are shown to stand out as privileged motives for the stereoselective preparation of such synthetically challenging molecular architectures. Finally, an overview of the main trends in the field is given. 1 Introduction 2 Five-Membered Rings 2.1 Arylation 2.2 Dynamic Kinetic Resolution 2.3 Ring Construction 2.4 Central-to-Axial Chirality Conversion and Chirality Transfer 2.5 Desymmetrization 3 Six-Membered Rings 3.1 Desymmetrization 3.2 (Dynamic) Kinetic Resolution 3.3 Ring Construction 3.4 Central-to-Axial Chirality Conversion 4 Conclusion [ABSTRACT FROM AUTHOR]