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Your search keyword '"Nikolaus Pizanis"' showing total 25 results
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25 results on '"Nikolaus Pizanis"'

1. Lung Transplantation for Adult Respiratory Distress Syndrome after SARS-CoV-2 Infection

Author

Achim Koch, Nikolaus Pizanis, Vasiliki Bessa, Frank Herbstreit, Erich Gulbins, Clemens Aigner, and Markus Kamler

Subjects
sars-cov-2, lung transplantation, sphingosine, Surgery, RD1-811
Abstract

Background The majority of patients with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection present mild symptoms. However, some patients develop severe acute respiratory distress syndrome (ARDS) and subsequent irreversible lung damage despite extracorporeal membrane oxygenation, leaving lung transplantation the ultimate therapeutically option. Case Description Here, we report a case of lung transplantation in a 31-year-old male recipient suffering from post-coronavirus disease 2019 respiratory failure with irreversible ARDS after prolonged extracorporeal membrane oxygenation therapy. Conclusion Patient selection criteria are elucidated. One relevant mechanism for susceptibility to SARS-CoV-2 in the respiratory system, the acid sphingomyelinase/ceramide system might be altered during infection with SARS-CoV-2.

Published
2022
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3. Introduction of An Ex-vivo-lung-perfusion System in Germany

Author

Achim Koch, Henning Carstens, Alexis Slama, Clemens Aigner, Nikolaus Pizanis, M Kamler, and O. Abou-Issa

Subjects
Pulmonary and Respiratory Medicine, Pathology, medicine.medical_specialty, business.industry, Ex vivo lung perfusion, Physiology, Medicine, Surgery, Cardiology and Cardiovascular Medicine, business
Published
2017

4. Does Traumatic Donor Cause of Death Influence Outcome after Lung Transplantation? A Single-Centre Analysis

Author

Kevin Pilarczyk, J. Heckmann, Nikolaus Pizanis, Jura Lubarski, Henning Carstens, Markus Kamler, and Heinz Jakob

Subjects
Adult, Male, Pulmonary and Respiratory Medicine, medicine.medical_specialty, Time Factors, Adolescent, Traumatic brain injury, medicine.medical_treatment, Medizin, Kaplan-Meier Estimate, 030204 cardiovascular system & hematology, Donor Selection, Young Adult, 03 medical and health sciences, Postoperative Complications, 0302 clinical medicine, Risk Factors, Cause of Death, Germany, Statistical significance, Brain Injuries, Traumatic, medicine, Humans, Lung transplantation, Young adult, Hypoxia, Brain, Aged, Cerebral Hemorrhage, Retrospective Studies, Cause of death, Brain Neoplasms, business.industry, Donor selection, Retrospective cohort study, Middle Aged, medicine.disease, Tissue Donors, Surgery, Transplantation, Treatment Outcome, 030228 respiratory system, Anesthesia, Female, Cardiology and Cardiovascular Medicine, business, Lung Transplantation
Abstract

Background Owing to the shortage of donor organs in lung transplantation (LuTX), liberalization of donor selection criteria has been proposed. However, some studies suggested that donor traumatic brain damage might influence posttransplantation allograft function. This article aimed to investigate the association of donor cause of death (DCD) and outcome after LuTX. Methods A retrospective analysis of 186 consecutive double LuTXs at our institution from January 2000 to December 2008 was performed. DCD was categorized into traumatic brain injury (TBI) and nontraumatic brain injury (NTBI). In addition, NTBI was sub classified as spontaneous intracerebral bleeding (B), hypoxic brain damage (H), and intracerebral neoplasia (N). Results DCD was classified as TBI in 50 patients (26.9%) and NTBI in 136 patients (73.1%): B in 112 patients (60.2%), H in 21 patients (11.3%), and N in 3 patients (1.6%). Young male donors predominated in group TBI (mean age 36.0 ± 14.5 vs. 42.8 ± 10.7, p Conclusion This study indicates that traumatic DCD does not affect outcome after LuTX. These results can be achieved with an ideal donor management combined with an individual case-to-case evaluation by an experienced LuTX surgeon.

Published
2015

6. ICU Controlled Delay for Acute Type A Aortic Dissection Repair after Intervention for Total Visceral Malperfusion: A Way Out of a Dilemma?

Author

T Konorza, T. Zoepf, H Jakob, Konstantinos Tsagakis, Raimund Erbel, M Kamler, and Nikolaus Pizanis

Subjects
Male, Pulmonary and Respiratory Medicine, medicine.medical_specialty, Critical Care, Ischemia, Hemodynamics, Radiography, Interventional, Blood Vessel Prosthesis Implantation, Fatal Outcome, Internal medicine, Intervention (counseling), medicine, Humans, Aged, 80 and over, Surgical repair, Aortic dissection, Cardiopulmonary Bypass, Aortic Aneurysm, Thoracic, business.industry, Middle Aged, medicine.disease, Surgery, Restitution, Aortic Dissection, Viscera, Regional Blood Flow, Acute type, Reperfusion Injury, Cardiology, Female, Cardiology and Cardiovascular Medicine, business, Visceral ischemia
Abstract

Despite immediate surgical repair of the entry site in acute thoracic aortic dissection with visceral malperfusion, the results are poor. Primary restitution of visceral flow by intervention might be one way to cope with this problem, but probably causes ischemia/reperfusion associated problems after prolonged complete visceral ischemia. In this report, we demonstrate a successful attempt of controlled delay of thoracic aortic surgical repair after visceral flow restitution with stable hemodynamics.

Published
2008

7. Health-related quality of life after heart and lung transplantation with prolonged intensive medical care

Author

H Jakob, Günter Marggraf, P Azhari, M Kamler, Mingo Beckmann, M Pennewiß, Nikolaus Pizanis, and Yesim Erim

Subjects
Pulmonary and Respiratory Medicine, Health related quality of life, medicine.medical_specialty, business.industry, medicine.medical_treatment, Medical care, Ambulatory care, Emergency medicine, medicine, Lung transplantation, Surgery, Cardiology and Cardiovascular Medicine, Intensive care medicine, business
Published
2010

8. Safe guidance of hybrid stentgraft placement and emergency true lumen cannulation in aortic dissection by angioscopy

Author

H Jakob, Paschalis Tossios, D Natour, M Kamler, P Massoudy, J. Benedik, Konstantinos Tsagakis, and Nikolaus Pizanis

Subjects
Pulmonary and Respiratory Medicine, Aortic dissection, medicine.medical_specialty, medicine.diagnostic_test, business.industry, Lumen (anatomy), Angioscopy, medicine.disease, Surgery, medicine, Radiology, Cardiology and Cardiovascular Medicine, business
Published
2010

10. To test or not to test – a question?

Author

Brigitte R. Osswald, V Steinweg, Nikolaus Pizanis, Stephan Knipp, Daniel Wendt, H Jakob, and Konstantinos Tsagakis

Subjects
Pulmonary and Respiratory Medicine, medicine.medical_specialty, business.industry, medicine, Surgery, Medical physics, Cardiology and Cardiovascular Medicine, business, Test (assessment)
Published
2010

11. Donor cause of death and mid-term survival in lung transplantation

Author

Kevin Pilarczyk, H Jakob, Konstantinos Tsagakis, P Massoudy, M Kamler, J. Heckmann, and Nikolaus Pizanis

Subjects
Pulmonary and Respiratory Medicine, Oncology, medicine.medical_specialty, business.industry, medicine.medical_treatment, Internal medicine, medicine, Lung transplantation, Surgery, Cardiology and Cardiovascular Medicine, business, Term (time), Cause of death
Published
2010

12. Serial CT-volumetry confirms shrinking of the false lumen throughout the descending aorta after antegrade stentgrafting for aortic dissection

Author

Raimund Erbel, H Jakob, Nikolaus Pizanis, H Kuehl, Paschalis Tossios, W. Kowalczyk, Konstantinos Tsagakis, M Kamler, Holger Eggebrecht, and H Juette

Subjects
Pulmonary and Respiratory Medicine, Aortic dissection, medicine.medical_specialty, business.industry, False lumen, medicine.disease, Descending aorta, medicine.artery, Medicine, Surgery, Radiology, Cardiology and Cardiovascular Medicine, business, Ct volumetry
Published
2009

13. Acute DeBakey type I aortic dissection: Is it justified, to treat the whole thoracic aorta with hybrid stentgraft?

Author

M Kamler, Nikolaus Pizanis, P Massoudy, Matthias Thielmann, U Herold, Konstantinos Tsagakis, and H Jakob

Subjects
Pulmonary and Respiratory Medicine, Aortic dissection, medicine.medical_specialty, business.industry, medicine.artery, Internal medicine, medicine, Cardiology, Thoracic aorta, Surgery, Cardiology and Cardiovascular Medicine, business, medicine.disease
Published
2008

14. Evaluation of Custodiol N for lung preservation in a porcine lung transplantation model

Author

Kevin Pilarczyk, M Kamler, Ursula Rauen, H Jakob, H. de Groot, Andrey V. Petrov, Nikolaus Pizanis, J. Heckmann, and Konstantinos Tsagakis

Subjects
Pulmonary and Respiratory Medicine, Transplantation, medicine.medical_specialty, Porcine lung, business.industry, Urology, medicine, Lung preservation, Custodiol-N, Surgery, Cardiology and Cardiovascular Medicine, business
Published
2008

15. Use of lungs from extended donors: No impact on short-term-outcome in lung transplant recipients

Author

Konstantinos Tsagakis, Nikolaus Pizanis, M Kamler, Heinz Jakob, Kevin Pilarczyk, A. Szabó, and Ivan Aleksic

Subjects
Pulmonary and Respiratory Medicine, medicine.medical_specialty, Lung, medicine.anatomical_structure, business.industry, medicine, Surgery, Cardiology and Cardiovascular Medicine, Intensive care medicine, business, Outcome (game theory), Term (time)
Published
2007

16. Techniques for bronchial anastomosis in lung transplantation

Author

Kevin Pilarczyk, P Massoudy, Ivan Aleksic, Nikolaus Pizanis, M Kamler, and Heinz Jakob

Subjects
Pulmonary and Respiratory Medicine, medicine.medical_specialty, business.industry, General surgery, medicine.medical_treatment, medicine, Lung transplantation, Surgery, Anastomosis, Cardiology and Cardiovascular Medicine, business
Published
2007

17. Benefit of biphasic perfusion in lung harvesting

Author

Ivan Aleksic, M Kamler, V Milekhin, C Yildirim, Heinz Jakob, Nikolaus Pizanis, and Konstantinos Tsagakis

Subjects
Pulmonary and Respiratory Medicine, medicine.medical_specialty, Lung, medicine.anatomical_structure, business.industry, Internal medicine, medicine, Cardiology, Surgery, Cardiology and Cardiovascular Medicine, business, Perfusion
Published
2006

19. Effect of intravenous PDE-5 inhibitor Sildenafil on pulmonary microcirculation n

Author

M Kamler, Ghazwan Butrous, R. Maykan, V Milekhin, Nikolaus Pizanis, and Heinz Jakob

Subjects
Pulmonary and Respiratory Medicine, medicine.medical_specialty, chemistry.chemical_compound, chemistry, Sildenafil, business.industry, Internal medicine, medicine, Cardiology, Surgery, Cardiology and Cardiovascular Medicine, Pulmonary microcirculation, business
Published
2006

20. PDE-5 inhibitor modified lung perfusion improves graft function after 24h ischemia

Author

Matthias Thielmann, Konstantinos Tsagakis, Heinz Jakob, V Milekhin, Nikolaus Pizanis, and M Kamler

Subjects
Pulmonary and Respiratory Medicine, medicine.medical_specialty, business.industry, Internal medicine, Ischemia, Cardiology, Medicine, Surgery, Lung perfusion, Cardiology and Cardiovascular Medicine, business, medicine.disease, Graft function
Published
2006

21. Early postoperative predictors of intestinal ischemia after cardiac surgery

Author

Heinz Jakob, Daniel Wendt, Rainer Leyh, Günter Marggraf, W. Niebel, Matthias Thielmann, Nikolaus Pizanis, and Konstantinos Tsagakis

Subjects
Pulmonary and Respiratory Medicine, medicine.medical_specialty, Intestinal ischemia, business.industry, Internal medicine, medicine, Cardiology, Surgery, Cardiology and Cardiovascular Medicine, business, Cardiac surgery
Published
2006

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