1. Klinik, Analytik und Verlauf einer Intoxikation mit dem Alkylphosphat Demeton-S-Methylsulfoxid (Metasystox R®)
- Author
-
Ziegenfuss T, Krämer T, and Kleinschmidt S
- Subjects
Obidoxime ,medicine.medical_specialty ,Resuscitation ,business.industry ,medicine.medical_treatment ,digestive, oral, and skin physiology ,General Medicine ,Critical Care and Intensive Care Medicine ,Hemoperfusion ,medicine.disease ,Gastric lavage ,Organophosphate poisoning ,Surgery ,Anesthesiology and Pain Medicine ,Respiratory failure ,Anesthesia ,Intensive care ,Emergency Medicine ,medicine ,Antidote ,business ,medicine.drug - Abstract
UNLABELLED We report on a 52-year old woman who had taken an unknown dose of the organophosphate insecticide Metasystox R with suicidal intention. Ingestion was followed by cardio-respiratory failure. After successful cardio-pulmonary resuscitation, main therapeutic principles were the immediate application of atropine and decontamination procedures such as gastric lavage, induction of diarrhoea and instillation of carbon. A single combined haemoperfusion and haemodialysis treatment was performed as a secondary elimination technique. After rapid toxicological analysis, obidoxime was administered as a supplementary antidote. After 14 days of treatment, the patient could leave the ICU with a complete restitution. CONCLUSION Our case report demonstrates the efficiency of immediate application of antidotal therapy (atropine), decontamination and elimination techniques even in case of cardio- respiratory failure after organophosphate poisoning. Toxicological analysis will be beneficial for diagnosis and the indication of further treatment with obidoxime.
- Published
- 1994