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52 results on '"Just, M"'

3. Investigating Denosumab as an add-on neoadjuvant treatment for RANK/L-positive or RANK/L-negative primary breast cancer and two different nab-Paclitaxel schedules – 2 × 2 factorial design (GeparX)

Author

Kümmel, S, additional, Minckwitz, G, additional, Vladimirova, V, additional, Nekljudova, V, additional, Wimberger, P, additional, Denkert, C, additional, Just, M, additional, Hanusch, C, additional, Stötzer, O, additional, Huober, J, additional, Hofmann, M, additional, Jackisch, C, additional, Blohmer, JU, additional, Schneeweiss, A, additional, Untch, M, additional, and Loibl, S, additional

Published
2018
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9. Androgenrezeptor (AR) und Forkhead BoxA1 (FOXA1) als Prognosefaktoren beim frühen HER2-negativen Mammakarzinom – eine translationale Substudie im Rahmen der prospektiven Phase-III-WSG-Plan B Studie

Author

Degenhardt, T, primary, Kreipe, HH, additional, Gluz, O, additional, Kates, RE, additional, Liedtke, C, additional, Kraemer, S, additional, Clemens, MR, additional, Nuding, B, additional, Reimer, T, additional, Aktas, B, additional, Kuemmel, S, additional, Just, M, additional, Lorenz-Salehi, F, additional, Uleer, C, additional, Stefek, A, additional, Heyl, V, additional, Würstlein, R, additional, Nitz, U, additional, Christgen, M, additional, and Harbeck, N, additional

Published
2016
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10. Ribociclib + letrozole for postmenopausal women with hormone receptor-positive (HR+), HER2-negative advanced breast cancer (ABC) who received no prior therapy for advanced disease

Author

Grischke, EM, primary, Nusch, A, additional, Marschner, N, additional, Abenhardt, W, additional, Wilke, J, additional, Decker, T, additional, Just, M, additional, Kümmel, S, additional, Kurbacher, C, additional, Marmé, F, additional, Overkamp, F, additional, Xuan, F, additional, Miller, M, additional, and Janni, W, additional

Published
2016
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11. Prospektive Phase-III PlanB-Studie: 5 Jahres Daten zum prognostischen Stellenwert von 21-Gen Recurrence-Score, zentralpathologischem Grading, ER, PR, Ki-67 Review beim frühem Hochrisiko HR+/HER2-negativen Mammakarzinom

Author

Reimer, T, primary, Gluz, O, additional, Nitz, U, additional, Christgen, M, additional, Kates, RE, additional, Clemens, M, additional, Krämer, S, additional, Nuding, B, additional, Aktas, B, additional, Kümmel, S, additional, Lorenz-Salehi, F, additional, Krabisch, P, additional, Just, M, additional, Augustin, D, additional, Liedtke, C, additional, Svedman, C, additional, Shak, S, additional, Würstlein, R, additional, Kreipe, HH, additional, and Harbeck, N, additional

Published
2016
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13. MR-tomographische Funktionsanalyse des linken Ventrikels

Author

Manfred Thelen, Just M, Raimund Erbel, P. Grebe, Michael B. Pitton, and K.-F. Kreitner

Subjects
Contraction (grammar), business.industry, Chemistry, Diastole, Blood volume, Left Ventricles, Nuclear magnetic resonance, medicine.anatomical_structure, Ventricle, Reference values, Circulatory system, medicine, Radiology, Nuclear Medicine and imaging, Nuclear medicine, business, End-systolic volume
Abstract

The following contribution presents a continuous MRT analysis of the contraction and relaxation processes of healthy left ventricles giving reference values for contraction and relaxation velocities. For the total ventricle we have Vsyst. r. total = 342 +/- 47% LVEDV/sec and Vdiast. r. total = 303 +/- 59% LVEDV/sec. In relation to the end-diastolic (tomographic) volume (EDSV) significantly greater changes in volume per unit of time were measured apically compared to basal (systolic: 411 +/- 89% EDSV/sec apical vs 261 +/- 35% EDSV/sec basal; diastolic: 810 +/- 145% EDSV/sec apical vs 245 +/- 70% EDSV/sec basal). Occurrence of the end-systolic minimal volumes of apical tomographic layers was delayed against the total ventricle by 22.4 +/- 7.9% t syst. Within the ventricle there was systolically a redistribution of the proportions of volume from apical to basal.

Published
1993

14. Magnetresonanztomographie bei chronischer Aortendissektion

Author

K.-F. Kreitner, Mohr-Kahaly S, Just M, P. Grebe, Raimund Erbel, Manfred Thelen, and Meyer J

Subjects
Aortic dissection, Aorta, medicine.medical_specialty, medicine.diagnostic_test, business.industry, Vascular disease, Ultrasound, medicine.disease, Endoscopy, Dissection, medicine.anatomical_structure, medicine.artery, Medicine, Radiology, Nuclear Medicine and imaging, Radiology, Thrombus, Esophagus, business
Abstract

17 patients with chronic aortic dissection were examined by MRI. In 12 patients, comparison between gradient echo sequences and SE sequences was possible. Gradient echo sequences, unlike SE sequences, permitted evaluation of flow in the true and false lumen, reliable differentiation between thrombus and flowing blood and clear delineation of the intimal flap. An additional comparison between transoesophageal ultrasound and MRT in 15 patients showed significant advantages in favour of MRI. In three patients MRI was able to detect more proximal origins of the dissection. Moreover, MRI allowed evaluation of the major aortic branches and their relation to the dissection; this was not possible with ultrasound. MRI plays an important role in the follow-up of chronic aortic dissections.

Published
1993

15. Hormonrezeptor-(HR)-Expression im Vergleich von Lokal- und Zentralpathologie sowie RT-PCR-basierte Analyse (Recurrence Score, RS, Oncotype DX): Ergebnisse aus der Plan B Studie

Author

Schumann, R von, primary, Gluz, O, additional, Nitz, U, additional, Clemens, M, additional, Lübbe, K, additional, Aktas, B, additional, Just, M, additional, Noesselt, T, additional, Henschen, S, additional, Hackmann, J, additional, Lorenz-Salehi, F, additional, Freese, K, additional, Svedmann, C, additional, Kates, R, additional, Kreipe, H, additional, Harbeck, N, additional, and Liedtke, C, additional

Published
2015
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16. Diskordanz der Prognosefaktoren beim frühen Mammakarzinom (Recurrence Score, zentrales Grading, Ki67) und deren Einfluss auf die frühe Rezidivierung in der prospektiven Phase III WSG-planB Studie

Author

Gluz, O, primary, Harbeck, N, additional, Kates, R, additional, Kreipe, H, additional, Christgen, M, additional, Hofmann, D, additional, Clemens, M, additional, Krämer, S, additional, Aktas, B, additional, Kümmel, S, additional, Reimer, T, additional, Kusche, M, additional, Heyl, V, additional, Lorenz-Salehi, F, additional, Just, M, additional, and Nitz, U, additional

Published
2015
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17. Meßfehlerschätzung bei der MR-tomographischen Volumetrie des linken Ventrikels mit Mehrschicht-Technik

Author

Manfred Thelen, Raimund Erbel, Just M, P. Grebe, Michael B. Pitton, and K.-F. Kreitner

Subjects
Physics, Observational error, Ejection fraction, business.industry, Stroke volume, medicine.anatomical_structure, Nuclear magnetic resonance, Volume (thermodynamics), Ventricle, medicine, End-diastolic volume, Radiology, Nuclear Medicine and imaging, Multislice, Nuclear medicine, business, End-systolic volume
Abstract

A multi-slice technique for MRT measurements of the left ventricular volume is much faster than the use of single-slice methods and is therefore better tolerated, leaving time for additional measurements. The end-diastolic left ventricular volume can be reliably measured by this method (123.3 +/- 13.5 ml vs. 124.1 +/- ml). The end-systolic volume is consistently overestimated by 23.7 +/- 18.3% compared with the reference value obtained by single slice measurements (47.9 +/- 8.9 ml vs 39.1 +/- 7.9 ml). Correspondingly, stroke volume and ejection fraction is underestimated on average by 10.6 +/- 9.7% and 10.6 +/- 7.6% respectively).

Published
1992

18. Stellenwert der MR-Tomographie bei akuten Schulterluxationen

Author

Just M, P. Grebe, Kreitner Kf, Oberbillig C, and M. Runkel

Subjects
musculoskeletal diseases, medicine.medical_specialty, Glenoid labrum, business.industry, Joint effusion, Surgery, Lesion, medicine.anatomical_structure, Edema, medicine, Tears, Radiology, Nuclear Medicine and imaging, Shoulder joint, Rotator cuff, medicine.symptom, business, Greater Tuberosity
Abstract

24 patients up to two weeks after primary traumatic shoulder dislocation were examined at 0.5 and 1.5 T. Surgical and/or arthroscopic correlation was available in 13, CT-arthrographic correlation in 16 patients. A joint effusion allowing sufficient evaluation of the capsulolabral complex was present in 21/24 (87.5%) cases. 11/14 patients with combined dislocated detachments of the glenoid labrum and capsular lesions were subsequently operated upon. Marrow edema of the humeral head was found in 16/19 Hill-Sachs lesions and in 4/5 fractures of the greater tuberosity. Two patients presented with a lesion of the long biceps tendon associated with rotator cuff tears and were also subsequently operated upon. MRI performed shortly after primary traumatic shoulder dislocation allows a comprehensive evaluation of the intraarticular lesions and decisively influences further therapy.

Published
1992

19. MR-Tomographie versus CT-Arthrographie bei glenohumeralen Instabilitäten

Author

Just M, Franz Schweden, Hans H. Schild, Oberbillig C, Kreitner Kf, P. Grebe, Schwickert Hc, M. Runkel, and Kirschner P

Subjects
musculoskeletal diseases, medicine.medical_specialty, Glenoid labrum, business.industry, Glenohumeral instability, Predictive value, Surgery, medicine.anatomical_structure, Joint capsule, Medicine, Upper limb, Radiology, Nuclear Medicine and imaging, Ct arthrography, Shoulder joint, Nuclear medicine, business, Prospective cohort study
Abstract

In a prospective study the diagnostic value of MRI compared to CT arthrography (CT-A) was evaluated in 26 patients with 27 instable shoulder joints. Surgical and/or arthroscopic correlation was available in all cases. Both methods showed a high accuracy (96% CT-A, 94% MRI) in the evaluation of the glenoid labrum. CT-A was significantly superior to MRI in the detection of capsular lesions (sensitivity 96% vs. 44%, accuracy 96% vs. 72%, negative predictive value 96% vs. 67%). CT-A and MRI results regarding humeral head fractures were similar; fractures of the glenoid rim were better detected by CT-A, the difference, however, was statistically not significant. Overall, CT-A proved to be superior to MRI, as lesions of the joint capsule were shown with greater certainty.

Published
1992

20. Zystische Raumforderungen der Samenblasen

Author

R. Hohenfellner, Manfred Thelen, R. A. Bürger, Just M, P. Grebe, and K.-F. Kreitner

Subjects
Lesion, medicine.medical_specialty, Cystic lesion, medicine.anatomical_structure, medicine.diagnostic_test, Prostate, business.industry, medicine, Radiology, Nuclear Medicine and imaging, Cystoscopy, Radiology, medicine.symptom, business
Abstract

Between October 1990 and March 1991, 8 patients with cystic lesions in the region of the posterior bladder wall, the seminal vesicles and the prostate were examined by MRI. In all cases there was accurate characterisation of the lesion and of its anatomy. In 3 patients with abnormalities in the retrovesical space there was very good agreement with the operative findings. 4 patients were treated conservatively. In these patients there was good agreement with the findings on cystoscopy, CT and sonography.

Published
1992

21. MR-Tomographie bei Hodenprozessen

Author

Manfred Thelen, Just M, P. Grebe, S. Melchior, R. A. Bürger, R. Hohenfellner, and K.-F. Kreitner

Subjects
endocrine system, medicine.medical_specialty, Contrast enhancement, medicine.diagnostic_test, business.industry, media_common.quotation_subject, Magnetic resonance imaging, medicine.disease, Tunica albuginea (ovaries), Parenchyma, medicine, Contrast (vision), Orchitis, Radiology, Nuclear Medicine and imaging, Radiology, Tomography, T2 weighted, business, media_common
Abstract

The value of T1-weighted sequences after intravenous administration of Gd-DTPA and of T2-weighted sequences was compared in 43 patients suspected of having scrotal abnormalities. T2-weighted sequences gave better demonstration of the tunica albuginea and better contrast between tumor and parenchyma. The two techniques were equally sensitive for demonstrating testicular tumors but orchitis was better demonstrated on the contrast enhanced sequences. Motion artifacts were less marked in the T1-weighted sequences with contrast enhancement. In selected cases, contrast enhancement may be a valuable addition to native protocols. Our experience has indicated that MRI provides specific findings in cases of orchitis which are clinically atypical; this facilitates the decision to conservative treatment and prevents unnecessary exploration of the testes.

Published
1992

22. MR-Tomographie bei Innenbandverletzungen des Kniegelenkes

Author

K.-F. Kreitner, P. Grebe, Manfred Thelen, Just M, J. Ahlers, and M. Runkel

Subjects
medicine.medical_specialty, business.industry, Meniscal tears, Anatomy, Knee Joint, medicine.anatomical_structure, hemic and lymphatic diseases, Ligament, Medicine, Radiology, Nuclear Medicine and imaging, Tomography, Radiology, business, Mri findings
Abstract

Frequency and characteristics of lesions of the medial collateral ligaments (MCL) were studied by MRI in 155 patients with trauma to the knee. There were abnormalities of the MCL in 38% of cases with ligamentous injuries and in 27% these were combined with meniscal tears. 11% of these patients showed isolated rupture of MCL and as a result of the MRI findings were treated conservatively. By means of T2*-weighted images the individual lesions could be accurately localised. Characteristic findings have been defined.

Published
1992

23. Sonographie bei Skelettmetastasen - Stellenwert im Vergleich zur Computertomographie und konventionellen Röntgendiagnostik

Author

Manfred Thelen, H. P. Rösler, Just M, and J. Kutzner

Subjects
Radiation therapy, Conventional radiography, business.industry, medicine.medical_treatment, Radiography, Ultrasound, medicine, Soft tissue, Radiology, Nuclear Medicine and imaging, Nuclear medicine, business, medicine.disease, Metastasis
Abstract

The value of CT, conventional radiography and ultrasound was compared in 40 patients with 52 skeletal metastases. For superficial lesions, the combination of sonography and conventional radiography was equivalent to CT in showing the extent of bone destruction and soft tissue involvement. As expected sonography was unsatisfactory for deeper lesions. Sonography can provide useful information for planning radiation therapy for superficial lesions, but it does not replace conventional radiography.

Published
1990

39. MR-Tomographie bei Hodenprozessen

Author

Just, M., primary, Melchior, S., additional, Grebe, P., additional, Kreitner, K.-F., additional, Bürger, R., additional, Hohenfellner, R., additional, and Thelen, M., additional

Published
1992
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