1. Sequence comparisons
- Author
-
Milkman, Roger and Bridges, Melissa McKane
- Subjects
Escherichia coli -- Genetic aspects ,Chromosome mapping -- Analysis ,Genetic recombination -- Research ,Biological sciences - Abstract
A 4,400-base pair stretch of DNA starting from the end of the trp operon and including tonB and some open reading frames were compared in Escherichia coli K12 and 36 ECOR strains. Comparative sequencing showed consistency in multilocus enzyme electrophoresis and analyses of restriction fragment length polymorphism suggesting that the observed linear discontinuities are due to recombination. The replacement patterns may be explained by incorporation of small or large entrant DNA fragments or through the cascade hypothesis.
- Published
- 1993