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Introduction: An increase in sympathetic activity caused by intermittent hypoxia and reoxygenation that develops an obstruction of the upper respiratory tract in obstructive sleep apnea syndrome (OSAS) results in cardiovascular and metabolic changes. This study aimed to assess the effects of OSAS on serum vitamin D and parathyroid hormone (PTH) levels. Methods: The study population comprised 103 male patients with newly diagnosed OSAS and 58 male non-apnoeic controls matched for age, sex, and body mass index (BMI). Serum calcium, phosphorus, vitamin D, and PTH levels were measured. Results: There were no significant differences between patients with OSAS and the controls in terms of age, sex, BMI, smoking status, hypertension, and hyperlipidemia. Serum vitamin D levels were significantly lower in the OSAS group than in the control group (22.4±7.5 ng/mL vs. 31±7.9 ng/mL, respectively; p<0.001), whereas PTH levels were significantly higher in the OSAS group than in the control group (56.6±18.8 pg/mLvs. 42.3±17.6 pg/mL, respectively; p<0.001). On subgroup analysis, vitamin D levels were significantly lower in patients with severe OSAS than in those with mild/moderate OSAS (p<0.001). Vitamin D levels significantly correlated with theapnea-hypopnea index, oxygen desaturation index, PTH levels, and mean oxygen saturation. Conclusion: These results showed that OSAS is associated with low vitamin D levels and elevated PTH levels, which is related severity of OSAS. [ABSTRACT FROM AUTHOR]

Objective: The aim of this study was to evaluate bone mineral density (BMD) and to discuss the potential risk factors for osteoporosis in four different occupational groups. Materials and Methods: In this study, 100 males who were admitted to our clinics for their periodic occupational controls and 40 healthy subjects were included. Demographic features of the participants were recorded. BMD was evaluated by Dual-energy x-ray absorptiometry (DXA) from lumbar vertebrae and proximal femur. Results: Participants were mainly from the following four occupational groups; accumulator manufacturers (n=30, 21.4%), painting workers (n=30, 21.4%), welders (n=15, 10.7%), and quartz miners (n=25, 17.9%) sectors. In addition, there were 40 healthy subjects (28.6%). Compared with the control group, femoral neck T-scores (p=0.023) and Z-scores (p=0.031) were significantly lower in miners. L2-L4 BMD values were significantly lower in accumulator manufacturers (p=0.041) and quartz miners (p=0.022) as compared with the control group. Conclusion: Workers in the accumulator and mining sectors had lower BMD than control subjects. Clinicians should keep in mind occupational risk factors related with chemical exposure for osteoporosis while questioning osteoporosis risk factors. [ABSTRACT FROM AUTHOR]

Copyright of Turkish Journal of Osteoporosis / Turk Osteoporoz Dergisi is the property of Galenos Yayinevi Tic. LTD. STI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Turkish Journal of Osteoporosis / Turk Osteoporoz Dergisi is the property of Galenos Yayinevi Tic. LTD. STI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Turkish Journal of Osteoporosis / Turk Osteoporoz Dergisi is the property of Galenos Yayinevi Tic. LTD. STI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)