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Coronary artery aneurysm/ectasia (CAE) is defined as a dilatation of a coronary artery segment to more than 1.5-fold normal size in diameter. The leading etiologic factor of CAE is atherosclerotic coronary artery disease, but it can be seen rarely secondary to inflammatory diseases in romatological diseases (e.g. Kawasaki disease, Takayasu’s arteritis, Systemic Lupus Erythematosus (SLE), rheumatoid arthritis). We present here in a giant coronary aneurysm, possible etiologic causes and treatment in a patient with SLE who had a previous coronary intervention. Treatment was performed successfully with a covered stent. We thought that the aneurysm was developed secondary to the drug eluting stent that was previously implanted while SLE was in remission. This case report emphasizes that coronary artery disease should be considered in SLE patients who do not have traditional risk factors for coronary artery disease.

Asymptomatic premature ventricular beats are most common presentation form of arrhyth-mia observed in patients with or without structural heart disease. In long term, frequent pre-mature ventricular beats can lead left ventricule failure in structurally normal heart. Here, we reported a case of premature ventricular complex-induced cardiomyopathy who applied to emergency department with acute heart failure and recovered promptly after catheter abla-tion of related arrhytmic focus.

Infliximab is an anti-tumor necrosis factor alpha agent, which is indicated for the treatment of resistant ankylosing spondylitis (AS). We presented a patient with AS who developed ventricular tachycardia after premature cessation of infliximab. Ventricular tachycardia did not recur after restarting of infliximab treatment. This case report remarked the significance of the suppression of inflammation in AS since the subclinical ventricular involvement may potentially lead to the fatal arrhythmias.

Aim: Angiotensin-converting enzyme (ACE) inhibitors and beta blockers were shown to be effec-tive in prevention of atrial fibrillation (AF) recurrences after electrical cardioversion, by interfering with atrial structural and electrical remodeling. In this study, we aimed to compare the effects of ACE inhibitor cilazapril and beta blocker metoprolol after cardioversion of AF in terms of sinus rhythm maintenance.Patients and Methods: The study population comprised 120 patients with persistent atrial fibril-lation (>7 days) who underwent successful cardioversion. Randomization into 3 groups was done after successful cardioversion. Group I (n=41) was treated with amiodarone, group II (n=41) was treated with amiodarone plus metoprolol, and group III (n=38) was treated with amiodarone plus cilazapril. The primary end-point of the study was the recurrence rates between groups at one year and with those who recurred, the time to recurrence of AF.Results: After 1 year follow-up, maintenance of sinus rhythm were similar among groups (Kaplan-Meier analysis, 24%, 37% and 26% respectively; log rank=0.3). There was no difference among groups with respect to time to recurrence of AF.Conclusion: Patients treated with amiodarone only, amiodarone plus metoprolol and amiodaro-ne plus cilazapril had similar rates of recurrence of AF.