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Start Over Author "Seganti, Giulio" Publisher frontline medical communications
2 results on '"Seganti, Giulio"'

1. Vesiculopustular eruption in a neonate with trisomy 21 syndrome as a clue of transient myeloproliferative disorders.

Author

Bambino Gesù Children’s Hospital – (Italy) Roma - Department of Neonatology, Piersigilli, Fiammetta, Diociaiuti, Andrea, Boldrini, Renata, Auriti, Cinzia, Curci, Marco, El Hachem, Maya, Seganti, Giulio, Bambino Gesù Children’s Hospital – (Italy) Roma - Department of Neonatology, Piersigilli, Fiammetta, Diociaiuti, Andrea, Boldrini, Renata, Auriti, Cinzia, Curci, Marco, El Hachem, Maya, and Seganti, Giulio

Abstract

We report the case of a vesiculopustular eruption associated with a transient myeloproliferative disorder (TMD) in a neonate with trisomy 21 syndrome. Examination of a skin biopsy showed a dermal mixed inflammatory infiltrate including atypical megakaryoblasts. As the white blood cell count spontaneously normalized, the eruption disappeared. This case report and review of the literature demonstrates that a vesiculopustular eruption could be an important clue to identify TMD in a neonate.

Published
2010

2. Vesiculopustular eruption in a neonate with trisomy 21 syndrome as a clue of transient myeloproliferative disorders.

Author

Piersigilli F, Diociaiuti A, Boldrini R, Auriti C, Curci M, El Hachem M, and Seganti G

Subjects
Biopsy, Female, Humans, Infant, Newborn, Leukocyte Count, Megakaryocyte Progenitor Cells metabolism, Myeloproliferative Disorders complications, Myeloproliferative Disorders etiology, Skin Diseases, Vesiculobullous diagnosis, Skin Diseases, Vesiculobullous pathology, Down Syndrome complications, Myeloproliferative Disorders diagnosis, Skin Diseases, Vesiculobullous etiology
Abstract

We report the case of a vesiculopustular eruption associated with a transient myeloproliferative disorder (TMD) in a neonate with trisomy 21 syndrome. Examination of a skin biopsy showed a dermal mixed inflammatory infiltrate including atypical megakaryoblasts. As the white blood cell count spontaneously normalized, the eruption disappeared. This case report and review of the literature demonstrates that a vesiculopustular eruption could be an important clue to identify TMD in a neonate.

Published
2010

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