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Your search keyword '"Li, Xueqian"' showing total 9 results
Start Over Author "Li, Xueqian" Publisher frontiers media sa
9 results on '"Li, Xueqian"'

1. Appropriate pre-transplant strategy for patients with myelodysplastic syndromes receiving allogeneic haematopoietic stem cell transplantation after myeloablative conditioning

Author

Wang, Hong, primary, Wang, Qingyuan, additional, Qi, Jiaqian, additional, Li, Xueqian, additional, Chu, Tiantian, additional, Qiu, Huiying, additional, Fu, Chengcheng, additional, Tang, Xiaowen, additional, Ruan, Changgeng, additional, Wu, Depei, additional, and Han, Yue, additional

Published
2023
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6. Prognostic Value of Thrombocytopenia in Myelodysplastic Syndromes After Hematopoietic Stem Cell Transplantation

Author

Wang, Hong, Qi, Jiaqian, Li, Xueqian, Chu, Tiantian, Qiu, Huiying, Fu, Chengcheng, Tang, Xiaowen, Ruan, Changgeng, Wu, Depei, and Han, Yue

Subjects
Cancer Research, Oncology
Abstract

Prolonged isolated thrombocytopenia (PT) is a common complication affecting the outcome of stem cell transplantation. In this study, we undertook a real-world study of 303 myelodysplastic syndrome (MDS) patients who received allogeneic hematopoietic stem cell transplantation (HSCT) between December 2007 and June 2018. 28.4% of MDS patients suffered from PT after HSCT. Survival analysis indicated that PT was associated with worse overall survival (OS) in MDS patients. The 2-year and 5-year OS in MDS patients with PT after HSCT were 49% and 47%, significantly worse than that of 68% and 60% in patients without PT (P=0.005). For RFS, patients with PT did not have an increased risk of disease relapse (P=0.964). After multivariate adjustment, PT was proved to be the independent risk factor associated with the worse OS (HR 1.49, 95% CI 1.00-2.21, P =0.048). We further analyzed risk factors associated with the occurrence of PT in MDS patients. Multiple logistic regression identified grade II-IV aGVHD, extensive chronic GVHD, hemorrhagic cystitis, and CMV activation as significant risk factors for developing PT. Among these variables, the Odds Ratio (OR) of grade II-IV aGVHD was the highest (P =0.001, OR: 2.65, 95% CI: 1.51-4.64). These data indicated the prognostic value of PT in MDS after HSCT. The identification of risk factors for PT may help improve patient management and lead to the design of effective treatment strategies.

Published
2022

7. Interferon-alpha responsible EPN3 regulates hepatitis B virus replication

Author

Li, Xueqian, primary, Wang, Zhe, additional, Zhou, Weiping, additional, Fu, Xuanhe, additional, Zhang, Yunpeng, additional, Sun, Ye, additional, Yang, Biao, additional, Bai, Yuxin, additional, Dai, Chunwei, additional, Xu, Xiaolun, additional, Cui, Fan, additional, Zhao, Ying, additional, Zhang, Yuping, additional, Wang, Bengang, additional, Li, Yingfang, additional, Muramatsu, Masamichi, additional, Wakae, Kousho, additional, and Liu, Guangyan, additional

Published
2022
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