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Acoustic energy, especially broadband low-frequency sound energy is part of the environmental mechanical energy acquisition cannot be ignored. Herein, a multi-tube parallel Helmholtz resonator-based triboelectric nanogenerator (MH-TENG) is investigated to reap sound energy in low-frequency noise environments. The designed MH-TENG consists of a modified Helmholtz resonator and a thin-film TENG transducer. The core materials of the TENG transducer are aluminum, FEP film, and carbon. To further clarify the influence of the modified Helmholtz resonator on the conversion performance of MH-TENG, the acoustic characteristics of the improved resonators are systematically studied. A series of experiments show that the multi-tube parallel Helmholtz resonator structure has a better sound wave collection effect. Meanwhile, the flexible film TENG can reduce the optimal output frequency of the device. The power generation performance and the bandwidth of the MH-TENG are significantly improved by adopting a multi-tube Helmholtz resonator. Within the frequency bandwidth range of 230 Hz, MH-TENG can effectively improve the efficiency of acoustic energy harvesting. 110 LEDs and an electronic thermometer can be powered by the sound-driven MH-TENG. In addition, the MH-TENG has a good capacitor charging performance, which is conducive to its application in ambient sound energy harvesting.

To research the emotional interaction between customers and service staff, single-modal stimuli are being used to activate subjects’ emotions while multimodal emotion stimuli with better efficiency are often neglected. This study aims to construct a multimodal emotion stimuli database (CCSIAS) with video records of real work status of 29 service staff and audio clips of interactions between customers and service staff by setting up wide-angle cameras and searching in company’s Ocean Engine for 15 consecutive days. First, we developed a tool to assess the emotional statuses of customers and service staff in Study 1. Second, 40 Masters and PhD students were invited to assess the audio and video data to evaluate the emotional states of customers and service staff in Study 2, using the tools developed in Study 1. Third, 118 participants were recruited to test the results from Study 2 to ensure the stability of the derived data. The results showed that 139 sets of stable emotional audio & video data were constructed (26 sets were high, 59 sets were medium and 54 sets were low). The amount of emotional information is important for the effective activation of participants’ emotional states, and the degree of emotional activation of video data is significantly higher than that of the audio data. Overall, it was shown that the study of emotional interaction phenomena requires a multimodal dataset. The CCSIAS (https://osf.io/muc86/) can extend the depth and breadth of emotional interaction research and can be applied to different emotional states between customers and service staff activation in the fields of organizational behavior and psychology.

Introduction: Pulmonary fibrosis (PF) is a fatal chronic lung disease that causes structural damage and decreased lung function and has a poor prognosis. Currently, there is no medicine that can truly cure PF. Vitamin E (VE) is a group of natural antioxidants with anticancer and antimutagenic properties. There have been a few reports about the attenuation of PF by VE in experimental animals, but the molecular mechanisms are not fully understood.Methods: Bleomycin-induced PF (BLM-PF) mouse model, and cultured mouse primary lung fibroblasts and MLE 12 cells were utilized. Pathological examination of lung sections, immunoblotting, immunofluorescent staining, and real-time PCR were conducted in this study.Results: We confirmed that VE significantly delayed the progression of BLM-PF and increased the survival rates of experimental mice with PF. VE suppressed the pathological activation and fibrotic differentiation of lung fibroblasts and epithelial-mesenchymal transition and alleviated the inflammatory response in BLM-induced fibrotic lungs and pulmonary epithelial cells in vitro. Importantly, VE reduced BLM-induced ferritin expression in fibrotic lungs, whereas VE did not exhibit iron chelation properties in fibroblasts or epithelial cells in vitro. Furthermore, VE protected against mitochondrial dysmorphology and normalized mitochondrial protein expression in BLM-PF lungs. Consistently, VE suppressed apoptosis in BLM-PF lungs and pulmonary epithelial cells in vitro.Discussion: Collectively, VE markedly inhibited BLM-induced PF through a complex mechanism, including improving iron metabolism and mitochondrial structure and function, mitigating inflammation, and decreasing the fibrotic functions of fibroblasts and epithelial cells. Therefore, VE presents a highly potential therapeutic against PF due to its multiple protective effects with few side effects.

In the voltage source power electronic converter, DC-link capacitors usually work as buffering elements between the DC and AC sides. The high failure rate and large space occupied by the DC-link capacitors directly affect the reliability and power density of the converters. The analysis and calculation of the DC-link capacitor current is crucial to achieve the refined design of converters. In this work, the analysis and calculation methods of DC-link capacitor current are divided into three categories, according to the calculation principle, namely, simulation method, RMS analysis method, and spectral analysis method, and their calculation methods are summarized. First, the types of capacitors and their characteristics are briefly introduced. Second, the three-phase two-level converter is taken as an example to introduce the basic principles, calculation steps, application scope, advantages, and disadvantages of the latter two methods in detail, as well as the influence of non-ideal factors, such as the output ripple on the calculation results. This work also discusses the calculation of the multi-level converter’s DC-link capacitor current spectrum and the current characteristics of multi-phase converters, which are rarely reported. Third, the problem of resonance between the DC-link capacitors and the DC bus inductor is introduced. For the distributed arrangement of multiple DC-link capacitors on DC bus converters, this study proposes a method based on a constant current source equivalent circuit, which can accurately calculate the DC-link capacitor current spectrum that is affected by loop current and resonance. Finally, the current problems and future directions of the DC-link capacitor design are pointed out.

BackgroundEmotions play a decisive and central role in the workplace, especially in the service-oriented enterprises. Due to the highly participatory and interactive nature of the service process, employees’ emotions are usually highly volatile during the service delivery process, which can have a negative impact on business performance. Therefore, it is important to effectively judge the emotional states of customer service staff.MethodsWe collected data on real-life work situations of call center employees in a large company. Three consecutive studies were conducted: first, the emotional states of 29 customer service staff were videotaped by wide-angle cameras. In Study 1, we constructed scoring criteria and auxiliary tools of picture-type scales through a free association test. In Study 2, two groups of experts were invited to evaluate the emotional states of customer service staff. In Study 3, based on the results in Study 2 and a multimodal emotional recognition method, a multimodal dataset was constructed to explore how each modality conveys the emotions of customer service staff in workplace.ResultsThrough the scoring by 2 groups of experts and 1 group of volunteers, we first developed a set of scoring criteria and picture-type scales with the combination of SAM scale for judging the emotional state of customer service staff. Then we constructed 99 (out of 297) sets of stable multimodal emotion datasets. Based on the comparison among the datasets, we found that voice conveys emotional valence in the workplace more significantly, and that facial expressions have more prominant connection with emotional arousal.ConclusionTheoretically, this study enriches the way in which emotion data is collected and can provide a basis for the subsequent development of multimodal emotional datasets. Practically, it can provide guidance for the effective judgment of employee emotions in the workplace.

Random flaps are widely used in tissue reconstruction, attributed to the lack of vascular axial limitation. Nevertheless, the distal end of the flap is prone to necrosis due to the lack of blood supply. Notoginseng triterpenes (NTs) are the active components extracted from Panax notoginseng, reducing oxygen consumption and improving the body’s tolerance to hypoxia. However, their role in random flap survival has not been elucidated. In this study, we used a mouse random skin flap model to verify that NT can promote cell proliferation and migration and that increasing blood perfusion can effectively improve the survival area of a skin flap. Our study also showed that the autophagy of random flaps after NT treatment was activated through the Beclin-1/VPS34/LC3 signaling pathway, and the therapeutic effect of NT significantly decreased after VPS34 IN inhibited autophagy. In conclusion, we have demonstrated that NT can significantly improve the survival rate of random flaps through the Beclin-1/VPS34/LC3 signaling pathway, suggesting that it might be a promising clinical treatment option.

Reducing neuronal death after spinal cord injury (SCI) is considered to be an important strategy for the renovation of SCI. Studies have shown that, as an important regulator of the development and maintenance of neural structure, acidic fibroblast growth factor (aFGF) has the role of tissue protection and is considered to be an effective drug for the treatment of SCI. Neural stem cells (NSCs) are rendered with the remarkable characteristics to self-replace and differentiate into a variety of cells, so it is promising to be used in cell transplantation therapy. Based on the facts above, our main aim of this research is to explore the role of NSCs expressing aFGF meditated by five hypoxia-responsive elements (5HRE) in the treatment of SCI by constructing AAV–5HRE–aFGF–NSCs and transplanting it into the area of SCI. Our research results showed that AAV–5HRE–aFGF–NSCs can effectively restore the motor function of rats with SCI. This was accomplished by inhibiting the expression of caspase 12/caspase 3 pathway, EIF2α–CHOP pathway, and GRP78 protein to inhibit apoptosis.