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IntroductionIn cognitive behavioral experiments, we often asked participants to make judgments within a deadline. However, the most common instruction of “do the task quickly and accurately” does not highlight the importance of the balance between being fast and accurate.MethodsOur research aimed to explore how instructions about speed or accuracy affect perceptual process, focus on event-related potentials (ERPs) and event-related oscillations (EROs) of two brain responses for visual stimuli, known as P1 and N1. Additionally, we compared the conventional analysis approach with principal component analysis (PCA) based methods to analyze P1 and N1 ERP amplitude and ERO power.ResultsThe results showed that individuals instructed to respond quickly had lower P1 amplitude and alpha ERO than those who prioritized accuracy, using the PCA-based approach. However, these two groups had no differences between groups in the N1 theta band using both methods. The traditional time-frequency analysis method could not detect any ERP or ERO distinctions between groups due to limitations in detecting specific components in time or frequency domains. That means PCA is effective in separating these components.DiscussionOur findings indicate that the instructions given regarding speed and accuracy impact perceptual process of subjects during cognitive behavioral experiments. We suggest that future researchers should choose their instructions carefully, considering the purpose of study.

IntroductionPreeclampsia, one of the leading causes of maternal and fetal morbidity and mortality, demands accurate predictive models for the lack of effective treatment. Predictive models based on machine learning algorithms demonstrate promising potential, while there is a controversial discussion about whether machine learning methods should be recommended preferably, compared to traditional statistical models.MethodsWe employed both logistic regression and six machine learning methods as binary predictive models for a dataset containing 733 women diagnosed with preeclampsia. Participants were grouped by four different pregnancy outcomes. After the imputation of missing values, statistical description and comparison were conducted preliminarily to explore the characteristics of documented 73 variables. Sequentially, correlation analysis and feature selection were performed as preprocessing steps to filter contributing variables for developing models. The models were evaluated by multiple criteria.ResultsWe first figured out that the influential variables screened by preprocessing steps did not overlap with those determined by statistical differences. Secondly, the most accurate imputation method is K-Nearest Neighbor, and the imputation process did not affect the performance of the developed models much. Finally, the performance of models was investigated. The random forest classifier, multi-layer perceptron, and support vector machine demonstrated better discriminative power for prediction evaluated by the area under the receiver operating characteristic curve, while the decision tree classifier, random forest, and logistic regression yielded better calibration ability verified, as by the calibration curve.ConclusionMachine learning algorithms can accomplish prediction modeling and demonstrate superior discrimination, while Logistic Regression can be calibrated well. Statistical analysis and machine learning are two scientific domains sharing similar themes. The predictive abilities of such developed models vary according to the characteristics of datasets, which still need larger sample sizes and more influential predictors to accumulate evidence.

Novel metaphors in literary texts (hereinafter referred to as literary metaphors) seem to be more creative and open-ended in meaning than metaphors in non-literary texts (non-literary metaphors). However, some disagreement still exists on how literary metaphors differ from non-literary metaphors. Therefore, this study explored the neural mechanisms of literary metaphors extracted from modern Chinese poetry by using the methods of Event-Related Potentials (ERPs) and Event-Related Spectral Perturbations (ERSPs), as compared with non-literary conventional metaphors and literal expressions outside literary texts. Forty-eight subjects were recruited to make the semantic relatedness judgment after reading the prime-target pairs in three linguistic conditions. According to the ERPs results, the earliest differences were presented during the time window of P200 component (170–260 ms) in the frontal and central areas, with the amplitude of P200 for literary metaphors more positive than the other two conditions, reflecting the early allocation of attention and the early conscious experience of the experimental stimuli. Meanwhile, significant differences were presented during the time window of N400 effect (430–530 ms), with the waveform of literary metaphors more negative than others in the frontal and central topography of scalp distributions, suggesting more efforts in retrieving conceptual knowledge for literary metaphors. The ERSPs analysis revealed that the frequency bands of delta and theta were both involved in the cognitive process of literary metaphor comprehension, with delta band distributed in the frontal and central scalp and theta band in parietal and occipital electrodes. Increases in the two power bands during different time windows provided extra evidences that the processing of literary metaphors required more attention and effort than non-literary metaphors and literal expressions in the semantic related tasks, suggesting that the cognitive process of literary metaphors was distinguished by different EEG spectral patterns.