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Start Over Author "Marianne, Agerholm" Publisher frontiers media s.a.
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1. AMP-activated protein kinase controls exercise training- and AICAR-induced increases in SIRT3 and MnSOD

Author

Josef eBrandauer, Marianne Agerholm Andersen, Holti eKellezi, Steve eRisis, Christian eFrøsig, Sara Gry Vienberg, and Jonas Thue Treebak

Subjects
AMPK, exercise training, ROS, sirt3, mitochondrial biogenesis, MnSOD, Physiology, QP1-981
Abstract

The mitochondrial protein deacetylase sirtuin (SIRT) 3 may mediate exercise training-induced increases in mitochondrial biogenesis and improvements in reactive oxygen species (ROS) handling. We determined the requirement of AMP-activated protein kinase (AMPK) for exercise training-induced increases in skeletal muscle abundance of SIRT3 and other mitochondrial proteins. Exercise training for 6.5 weeks increased SIRT3 (p

Published
2015
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