1. QuantiFERON-TB reversion in children and adolescents with tuberculosis
- Author
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Paula Rodríguez-Molino, Araceli González Sánchez, Antoni Noguera-Julián, Aleix Soler-García, Patricia Martínez Paz, Ana Méndez-Echevarría, Fernando Baquero-Artigao, Miguel González Muñoz, María Jesús Ruíz-Serrano, Manuel Monsonís, Rocío Sánchez León, Jesús Saavedra-Lozano, Begoña Santiago-García, and Talía Sainz
- Subjects
QuantiFERON-TB ,reversion rate ,tuberculosis ,children ,adolescents ,Immunologic diseases. Allergy ,RC581-607 - Abstract
We analyzed 136 children with tuberculosis disease or infection and a positive QuantiFERON-TB (QFT) assay, followed-up for a median of 21 months (0.4-11years). QFT reversed in 16.9% of cases, with significant decreases in TB1 (-1.72 vs. -0.03 IU/ml, p=0.001) and TB2 (-1.65 vs. -0.43 IU/ml, p=0.005) levels compared to non-reverters. We found a higher QFT reversion rate among children under 5 years (25.0% vs 11.9%, p=0.042), and those with TST induration
- Published
- 2024
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