1. Measurements of peri-prostatic adipose tissue by MRI predict bone metastasis in patients with newly diagnosed prostate cancer
- Author
-
Bo-Hao Liu, Yun-Hua Mao, Xiao-Yang Li, Rui-Xiang Luo, Wei-An Zhu, Hua-Bin Su, Heng-Da Zeng, Chu-Hao Chen, Xiao Zhao, Chen Zou, and Yun Luo
- Subjects
prostate cancer ,metastasis ,peri-prostatic adipose tissue ,nomogram ,MRI ,Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,RC254-282 - Abstract
ObjectivesTo investigate the role of MRI measurements of peri-prostatic adipose tissue (PPAT) in predicting bone metastasis (BM) in patients with newly diagnosed prostate cancer (PCa).MethodsWe performed a retrospective study on 156 patients newly diagnosed with PCa by prostate biopsy between October 2010 and November 2022. Clinicopathologic characteristics were collected. Measurements including PPAT volume and prostate volume were calculated by MRI, and the normalized PPAT (PPAT volume/prostate volume) was computed. Independent predictors of BM were determined by univariate and multivariate logistic regression analysis, and a new nomogram was developed based on the predictors. Receiver operating characteristic (ROC) curves were used to estimate predictive performance.ResultsPPAT and normalized PPAT were associated with BM (P
- Published
- 2024
- Full Text
- View/download PDF