1. Comparison of Unipolar and Bipolar Voltage Mapping for Localization of Left Atrial Arrhythmogenic Substrate in Patients With Atrial Fibrillation
- Author
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Deborah, Nairn, Heiko, Lehrmann, Björn, Müller-Edenborn, Steffen, Schuler, Thomas, Arentz, Olaf, Dössel, Amir, Jadidi, and Axel, Loewe
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arrhythmogenic substrate ,lcsh:QP1-981 ,Physiology ,atrial fibrillation ,ddc:620 ,bipolar voltage mapping ,low voltage areas ,lcsh:Physiology ,Engineering & allied operations ,Original Research ,unipolar voltage mapping - Abstract
Background: Presence of left atrial low voltage substrate in bipolar voltage mapping is associated with increased arrhythmia recurrences following pulmonary vein isolation for atrial fibrillation (AF). Besides local myocardial fibrosis, bipolar voltage amplitudes may be influenced by inter-electrode spacing and bipole-to-wavefront-angle. It is unclear to what extent these impact low voltage areas (LVA) in the clinical setting. Alternatively, unipolar electrogram voltage is not affected by these factors but requires advanced filtering. Objectives: To assess the relationship between bipolar and unipolar voltage mapping in sinus rhythm (SR) and AF and identify if the electrogram recording mode affects the quantification and localization of LVA. Methods: Patients (n = 28, 66±7 years, 46% male, 82% persistent AF, 32% redo-procedures) underwent high-density (>1,200 sites, 20 ± 10 sites/cm2, using a 20-pole 2-6-2 mm-spaced Lasso) voltage mapping in SR and AF. Bipolar LVA were defined using four different thresholds described in literature
- Published
- 2020
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