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Your search keyword '"Cesari, Eleonora"' showing total 2 results
Start Over Author "Cesari, Eleonora" Publisher firenze university press
2 results on '"Cesari, Eleonora"'

1. Evaluation of the combined inhibition of alternative splicing and EZH2 activity as pro-immunogenic treatment for triple-negative breast cancers.

Author

Medici, Vanessa, Cesari, Eleonora, Caggiano, Cinzia, Pieraccioli, Marco, Ciucci, Alessandra, Di Leone, Alba, Sanchez, Martin, Masetti, Riccardo, Sette, Claudio, and Naro, Chiara

Abstract

The article focuses on exploring a potential pro-immunogenic treatment for triple-negative breast cancers (TNBC) by combining the inhibition of alternative splicing with EZH2 activity, aiming to enhance tumor immunogenicity and potentially improve therapeutic outcomes for TNBC patients.

Published
2023

2. The RNA binding protein QKI guides a pro-mesenchymal splicing program driving a subtype switch and limiting outcome in pancreatic cancer.

Author

Ruta, Veronica, Naro, Chiara, Pieraccioli, Marco, Archibugi, Livia, Cesari, Eleonora, Panzeri, Valentina, Quero, Giuseppe, Alfieri, Sergio, Doglioni, Claudio, Kleger, Alexander, Capurso, Gabriele, and Sette, Claudio

Abstract

The article focuses on the identification of a subtype-specific splicing signature in pancreatic ductal adenocarcinoma (PDAC) associated with prognosis, with the splicing factor QKI playing a key role in promoting the aggressive basal-like subtype and its associated poor clinical.

Published
2023

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