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1. Additional file 1: Figure S1. of Validation of genotype imputation in Southeast Asian populations and the effect of single nucleotide polymorphism annotation on imputation outcome

Author

Worachart Lert-Itthiporn, Bhoom Suktitipat, Grove, Harald, Anavaj Sakuntabhai, Prida Malasit, Nattaya Tangthawornchaikul, Matsuda, Fumihiko, and Prapat Suriyaphol

Abstract

Long distance LD pr. Mb separated by the chromosome for each population LD for each SNP pair with a distance between 10Â kb and 1Â Mb taken into account. Figure S2. Accuracy and yield of imputation between each location of SNPs. Figure S3. Comparing minor allele frequencies of SNPs between imputed and actual genotypes before quality control of imputed results separately plot by each SNP location. Figure S4. Comparing allele frequencies of SNPs between imputed and actual genotypes after quality control of imputed results separately plotted by each SNP location. Figure S5. Proportion of SNPs with lower AF after imputation vs initial AF. Figure S6. Comparing p-values between cases and controls of SNPs between imputed and actual genotypes before quality control of imputed results separately plotted by each SNP location. Figure S7. Comparing p-values between cases and controls of SNPs between imputed and actual genotypes after quality control of imputed results separately plotted according to each SNP location. Figure S8. Average linkage disequilibrium as r-squared for each region. SNPs were assigned to gene locations. Figure S9. LD, measured as r2, plotted against physical distance. (PDF 1286Â kb)

Published
2018
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2. Additional file 3: of Genetic determinants of anti-malarial acquired immunity in a large multi-centre study

Author

Shelton, Jennifer, Corran, Patrick, Risley, Paul, Nilupa Silva, Hubbart, Christina, Jeffreys, Anna, Rowlands, Kate, Craik, Rachel, Cornelius, Victoria, Hensmann, Meike, Molloy, Sile, Sepulveda, Nuno, Taane Clark, Band, Gavin, Clarke, Geraldine, Spencer, Christopher, Kerasidou, Angeliki, Campino, Susana, Auburn, Sarah, Tall, Adama, Alioune Ly, Mercereau-Puijalon, Odile, Anavaj Sakuntabhai, Abdoulaye DjimdĂŠ, Boubacar Maiga, Ousmane TourĂŠ, Ogobara Doumbo, Amagana Dolo, Troye-Blomberg, Marita, Mangano, Valentina, Verra, Frederica, Modiano, David, Bougouma, Edith, Sodiomon Sirima, Muntaser Ibrahim, Hussain, Ayman, Eid, Nahid, Abier Elzein, Mohammed, Hiba, Elhassan, Ahmed, Elhassan, Ibrahim, Williams, Thomas, Ndila, Carolyne, Macharia, Alexander, Marsh, Kevin, Alphaxard Manjurano, Reyburn, Hugh, Lemnge, Martha, Deus Ishengoma, Carter, Richard, Karunaweera, Nadira, Fernando, Deepika, Rajika Dewasurendra, Drakeley, Christopher, Riley, Eleanor, Kwiatkowski, Dominic, and Rockett, Kirk

Abstract

Additional File LFST1A: Details of gene regions selected for genotyping and the SNP assay design details. This file contains a list of the genes from which SNPs were selected and typed for this study. Information is provided on the gene and its genomic location with respect to the Human Reference genome build GRCh37. Also provided is a table containing the assay design details for each SNP used in this study for the Agena Biosciences iPLEX genotyping platform. SNPs are grouped into multiplexes as assigned by the assay design software.

Published
2015
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3. Additional file 17: of Genetic determinants of anti-malarial acquired immunity in a large multi-centre study

Author

Shelton, Jennifer, Corran, Patrick, Risley, Paul, Nilupa Silva, Hubbart, Christina, Jeffreys, Anna, Rowlands, Kate, Craik, Rachel, Cornelius, Victoria, Hensmann, Meike, Molloy, Sile, Sepulveda, Nuno, Taane Clark, Band, Gavin, Clarke, Geraldine, Spencer, Christopher, Kerasidou, Angeliki, Campino, Susana, Auburn, Sarah, Tall, Adama, Alioune Ly, Mercereau-Puijalon, Odile, Anavaj Sakuntabhai, Abdoulaye DjimdĂŠ, Boubacar Maiga, Ousmane TourĂŠ, Ogobara Doumbo, Amagana Dolo, Troye-Blomberg, Marita, Mangano, Valentina, Verra, Frederica, Modiano, David, Bougouma, Edith, Sodiomon Sirima, Muntaser Ibrahim, Hussain, Ayman, Eid, Nahid, Abier Elzein, Mohammed, Hiba, Elhassan, Ahmed, Elhassan, Ibrahim, Williams, Thomas, Ndila, Carolyne, Macharia, Alexander, Marsh, Kevin, Alphaxard Manjurano, Reyburn, Hugh, Lemnge, Martha, Deus Ishengoma, Carter, Richard, Karunaweera, Nadira, Fernando, Deepika, Rajika Dewasurendra, Drakeley, Christopher, Riley, Eleanor, Kwiatkowski, Dominic, and Rockett, Kirk

Abstract

Additional Figure SF5: Plot for 178 SNPs with logged anti-malarial antibody levels. Plot for the P-values of the analyses of 178 SNPs with logged anti-malarial antibody levels Adjusted for age, gender, parasite density, village (>20), ethnicity (>20), sample month (>20) and study. This is an extension to that shown in the main text and is a reduced dataset as not all sites provided parasitaemia data.

Published
2015
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5. Additional file 2. of Risk factors associated with asthma, atopic dermatitis and rhinoconjunctivitis in a rural Senegalese cohort

Author

Herrant, Magali, Cheikh Loucoubar, Boufkhed, Sabah, BassèNe, Hubert, Fatoumata Sarr, Baril, Laurence, Mercereau-Puijalon, Odile, MÊcheri, Salaheddine, Anavaj Sakuntabhai, and Paul, Richard

Subjects
immune system diseases, education, otorhinolaryngologic diseases, respiratory system, respiratory tract diseases
Abstract

Allergy classification criteria, description of ISAAC variables and details of allergens and immunoglobulin E titres

Published
2015
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6. Additional file 16: of Genetic determinants of anti-malarial acquired immunity in a large multi-centre study

Author

Shelton, Jennifer, Corran, Patrick, Risley, Paul, Nilupa Silva, Hubbart, Christina, Jeffreys, Anna, Rowlands, Kate, Craik, Rachel, Cornelius, Victoria, Hensmann, Meike, Molloy, Sile, Sepulveda, Nuno, Taane Clark, Band, Gavin, Clarke, Geraldine, Spencer, Christopher, Kerasidou, Angeliki, Campino, Susana, Auburn, Sarah, Tall, Adama, Alioune Ly, Mercereau-Puijalon, Odile, Anavaj Sakuntabhai, Abdoulaye DjimdĂŠ, Boubacar Maiga, Ousmane TourĂŠ, Ogobara Doumbo, Amagana Dolo, Troye-Blomberg, Marita, Mangano, Valentina, Verra, Frederica, Modiano, David, Bougouma, Edith, Sodiomon Sirima, Muntaser Ibrahim, Hussain, Ayman, Eid, Nahid, Abier Elzein, Mohammed, Hiba, Elhassan, Ahmed, Elhassan, Ibrahim, Williams, Thomas, Ndila, Carolyne, Macharia, Alexander, Marsh, Kevin, Alphaxard Manjurano, Reyburn, Hugh, Lemnge, Martha, Deus Ishengoma, Carter, Richard, Karunaweera, Nadira, Fernando, Deepika, Rajika Dewasurendra, Drakeley, Christopher, Riley, Eleanor, Kwiatkowski, Dominic, and Rockett, Kirk

Subjects
3. Good health
Abstract

Additional Table ST10: Meta-analysis p-values obtained for 178 SNPs passing QC criteria detailed in materials and methods. Details of the analyses for each SNP and antibody across all sites for different genetic inheritance models.

7. Additional file 10: of Genetic determinants of anti-malarial acquired immunity in a large multi-centre study

Author

Shelton, Jennifer, Corran, Patrick, Risley, Paul, Nilupa Silva, Hubbart, Christina, Jeffreys, Anna, Rowlands, Kate, Craik, Rachel, Cornelius, Victoria, Hensmann, Meike, Molloy, Sile, Sepulveda, Nuno, Taane Clark, Band, Gavin, Clarke, Geraldine, Spencer, Christopher, Kerasidou, Angeliki, Campino, Susana, Auburn, Sarah, Tall, Adama, Alioune Ly, Mercereau-Puijalon, Odile, Anavaj Sakuntabhai, Abdoulaye DjimdĂŠ, Boubacar Maiga, Ousmane TourĂŠ, Ogobara Doumbo, Amagana Dolo, Troye-Blomberg, Marita, Mangano, Valentina, Verra, Frederica, Modiano, David, Bougouma, Edith, Sodiomon Sirima, Muntaser Ibrahim, Hussain, Ayman, Eid, Nahid, Abier Elzein, Mohammed, Hiba, Elhassan, Ahmed, Elhassan, Ibrahim, Williams, Thomas, Ndila, Carolyne, Macharia, Alexander, Marsh, Kevin, Alphaxard Manjurano, Reyburn, Hugh, Lemnge, Martha, Deus Ishengoma, Carter, Richard, Karunaweera, Nadira, Fernando, Deepika, Rajika Dewasurendra, Drakeley, Christopher, Riley, Eleanor, Kwiatkowski, Dominic, and Rockett, Kirk

Subjects
3. Good health
Abstract

Additional figure SF4: Scatter plot of the correlations between residuals from the antibody linear regression models with non-genetic factors at each site and age-group. This plot shows the pairwise correlations (as r2) for each malariaâ malaria antibody pair as a function of each study site. The sites are ordered according to malaria microscopically-positive-prevalence recorded at sample collection (low to high). Several panels are shown according to age-group.

8. Additional file 4: of Genetic determinants of anti-malarial acquired immunity in a large multi-centre study

Author

Shelton, Jennifer, Corran, Patrick, Risley, Paul, Nilupa Silva, Hubbart, Christina, Jeffreys, Anna, Rowlands, Kate, Craik, Rachel, Cornelius, Victoria, Hensmann, Meike, Molloy, Sile, Sepulveda, Nuno, Taane Clark, Band, Gavin, Clarke, Geraldine, Spencer, Christopher, Kerasidou, Angeliki, Campino, Susana, Auburn, Sarah, Tall, Adama, Alioune Ly, Mercereau-Puijalon, Odile, Anavaj Sakuntabhai, Abdoulaye DjimdĂŠ, Boubacar Maiga, Ousmane TourĂŠ, Ogobara Doumbo, Amagana Dolo, Troye-Blomberg, Marita, Mangano, Valentina, Verra, Frederica, Modiano, David, Bougouma, Edith, Sodiomon Sirima, Muntaser Ibrahim, Hussain, Ayman, Eid, Nahid, Abier Elzein, Mohammed, Hiba, Elhassan, Ahmed, Elhassan, Ibrahim, Williams, Thomas, Ndila, Carolyne, Macharia, Alexander, Marsh, Kevin, Alphaxard Manjurano, Reyburn, Hugh, Lemnge, Martha, Deus Ishengoma, Carter, Richard, Karunaweera, Nadira, Fernando, Deepika, Rajika Dewasurendra, Drakeley, Christopher, Riley, Eleanor, Kwiatkowski, Dominic, and Rockett, Kirk

Subjects
3. Good health
Abstract

MalariaGEN Supplementary Sample Handling Procedures. This file includes more detail on sample handling procedures including extracting DNA, genotyping methodology, ELISA protocols with ELISA data processing.

9. Additional file 1: of Evaluation of the performances of six commercial kits designed for dengue NS1 and anti-dengue IgM, IgG and IgA detection in urine and saliva clinical specimens

Author

Anne-Claire Andries, Veasna Duong, Sivuth Ong, Sopheaktra Ros, Anavaj Sakuntabhai, Horwood, Paul, Dussart, Philippe, and Buchy, Philippe

Subjects
viruses, virus diseases, biochemical phenomena, metabolism, and nutrition, 3. Good health
Abstract

Characteristics of the rapid diagnostic tests for NS1, anti-DENV IgG/IgM and anti-DENV IgA detection in saliva and urine according to the manufacturerâ s instructions. (PDF 87 kb)

10. Additional file 2: of Evaluation of the performances of six commercial kits designed for dengue NS1 and anti-dengue IgM, IgG and IgA detection in urine and saliva clinical specimens

Author

Anne-Claire Andries, Veasna Duong, Sivuth Ong, Sopheaktra Ros, Anavaj Sakuntabhai, Horwood, Paul, Dussart, Philippe, and Buchy, Philippe

Subjects
viruses, parasitic diseases, virus diseases, cardiovascular diseases, biochemical phenomena, metabolism, and nutrition, 3. Good health
Abstract

Concordance between RDTs and IPC ELISAs for NS1, anti-DENV IgG/IgM and anti-DENV IgA detection in saliva and urine. (PDF 29 kb)

11. Additional file 9: of Genetic determinants of anti-malarial acquired immunity in a large multi-centre study

Author

Shelton, Jennifer, Corran, Patrick, Risley, Paul, Nilupa Silva, Hubbart, Christina, Jeffreys, Anna, Rowlands, Kate, Craik, Rachel, Cornelius, Victoria, Hensmann, Meike, Molloy, Sile, Sepulveda, Nuno, Taane Clark, Band, Gavin, Clarke, Geraldine, Spencer, Christopher, Kerasidou, Angeliki, Campino, Susana, Auburn, Sarah, Tall, Adama, Alioune Ly, Mercereau-Puijalon, Odile, Anavaj Sakuntabhai, Abdoulaye DjimdĂŠ, Boubacar Maiga, Ousmane TourĂŠ, Ogobara Doumbo, Amagana Dolo, Troye-Blomberg, Marita, Mangano, Valentina, Verra, Frederica, Modiano, David, Bougouma, Edith, Sodiomon Sirima, Muntaser Ibrahim, Hussain, Ayman, Eid, Nahid, Abier Elzein, Mohammed, Hiba, Elhassan, Ahmed, Elhassan, Ibrahim, Williams, Thomas, Ndila, Carolyne, Macharia, Alexander, Marsh, Kevin, Alphaxard Manjurano, Reyburn, Hugh, Lemnge, Martha, Deus Ishengoma, Carter, Richard, Karunaweera, Nadira, Fernando, Deepika, Rajika Dewasurendra, Drakeley, Christopher, Riley, Eleanor, Kwiatkowski, Dominic, and Rockett, Kirk

Subjects
3. Good health
Abstract

Additional figure SF3: Heatmap matrix plot of the correlations between residuals from the antibody linear regression models with non-genetic factors at each site. Matrix plot of the pairwise correlations as r2 between antibody titres using data from all sites.

12. Additional file 14: of Genetic determinants of anti-malarial acquired immunity in a large multi-centre study

Author

Shelton, Jennifer, Corran, Patrick, Risley, Paul, Nilupa Silva, Hubbart, Christina, Jeffreys, Anna, Rowlands, Kate, Craik, Rachel, Cornelius, Victoria, Hensmann, Meike, Molloy, Sile, Sepulveda, Nuno, Taane Clark, Band, Gavin, Clarke, Geraldine, Spencer, Christopher, Kerasidou, Angeliki, Campino, Susana, Auburn, Sarah, Tall, Adama, Alioune Ly, Mercereau-Puijalon, Odile, Anavaj Sakuntabhai, Abdoulaye DjimdĂŠ, Boubacar Maiga, Ousmane TourĂŠ, Ogobara Doumbo, Amagana Dolo, Troye-Blomberg, Marita, Mangano, Valentina, Verra, Frederica, Modiano, David, Bougouma, Edith, Sodiomon Sirima, Muntaser Ibrahim, Hussain, Ayman, Eid, Nahid, Abier Elzein, Mohammed, Hiba, Elhassan, Ahmed, Elhassan, Ibrahim, Williams, Thomas, Ndila, Carolyne, Macharia, Alexander, Marsh, Kevin, Alphaxard Manjurano, Reyburn, Hugh, Lemnge, Martha, Deus Ishengoma, Carter, Richard, Karunaweera, Nadira, Fernando, Deepika, Rajika Dewasurendra, Drakeley, Christopher, Riley, Eleanor, Kwiatkowski, Dominic, and Rockett, Kirk

Subjects
parasitic diseases, 3. Good health
Abstract

Additional Table ST8: Results of linear regression analysis investigating the effect of age, gender, malaria status as determined by microscopy and bednet use* on logged antibody levels to AMA1, MSP1, MSP2, NANP and IgE. This table shows the results of the analysis of antibody levels with bednet use. Results shown as betas indicating the direction of effect of the clinical covariates on antibody levels.

13. Additional file 10: of Genetic determinants of anti-malarial acquired immunity in a large multi-centre study

Author

Shelton, Jennifer, Corran, Patrick, Risley, Paul, Nilupa Silva, Hubbart, Christina, Jeffreys, Anna, Rowlands, Kate, Craik, Rachel, Cornelius, Victoria, Hensmann, Meike, Molloy, Sile, Sepulveda, Nuno, Taane Clark, Band, Gavin, Clarke, Geraldine, Spencer, Christopher, Kerasidou, Angeliki, Campino, Susana, Auburn, Sarah, Tall, Adama, Alioune Ly, Mercereau-Puijalon, Odile, Anavaj Sakuntabhai, Abdoulaye DjimdĂŠ, Boubacar Maiga, Ousmane TourĂŠ, Ogobara Doumbo, Amagana Dolo, Troye-Blomberg, Marita, Mangano, Valentina, Verra, Frederica, Modiano, David, Bougouma, Edith, Sodiomon Sirima, Muntaser Ibrahim, Hussain, Ayman, Eid, Nahid, Abier Elzein, Mohammed, Hiba, Elhassan, Ahmed, Elhassan, Ibrahim, Williams, Thomas, Ndila, Carolyne, Macharia, Alexander, Marsh, Kevin, Alphaxard Manjurano, Reyburn, Hugh, Lemnge, Martha, Deus Ishengoma, Carter, Richard, Karunaweera, Nadira, Fernando, Deepika, Rajika Dewasurendra, Drakeley, Christopher, Riley, Eleanor, Kwiatkowski, Dominic, and Rockett, Kirk

Subjects
3. Good health
Abstract

Additional figure SF4: Scatter plot of the correlations between residuals from the antibody linear regression models with non-genetic factors at each site and age-group. This plot shows the pairwise correlations (as r2) for each malariaâ malaria antibody pair as a function of each study site. The sites are ordered according to malaria microscopically-positive-prevalence recorded at sample collection (low to high). Several panels are shown according to age-group.

14. Additional file 7: of Genetic determinants of anti-malarial acquired immunity in a large multi-centre study

Author

Shelton, Jennifer, Corran, Patrick, Risley, Paul, Nilupa Silva, Hubbart, Christina, Jeffreys, Anna, Rowlands, Kate, Craik, Rachel, Cornelius, Victoria, Hensmann, Meike, Molloy, Sile, Sepulveda, Nuno, Taane Clark, Band, Gavin, Clarke, Geraldine, Spencer, Christopher, Kerasidou, Angeliki, Campino, Susana, Auburn, Sarah, Tall, Adama, Alioune Ly, Mercereau-Puijalon, Odile, Anavaj Sakuntabhai, Abdoulaye DjimdĂŠ, Boubacar Maiga, Ousmane TourĂŠ, Ogobara Doumbo, Amagana Dolo, Troye-Blomberg, Marita, Mangano, Valentina, Verra, Frederica, Modiano, David, Bougouma, Edith, Sodiomon Sirima, Muntaser Ibrahim, Hussain, Ayman, Eid, Nahid, Abier Elzein, Mohammed, Hiba, Elhassan, Ahmed, Elhassan, Ibrahim, Williams, Thomas, Ndila, Carolyne, Macharia, Alexander, Marsh, Kevin, Alphaxard Manjurano, Reyburn, Hugh, Lemnge, Martha, Deus Ishengoma, Carter, Richard, Karunaweera, Nadira, Fernando, Deepika, Rajika Dewasurendra, Drakeley, Christopher, Riley, Eleanor, Kwiatkowski, Dominic, and Rockett, Kirk

Subjects
Statistics::Machine Learning, Statistics::Theory, Statistics::Methodology, Statistics::Computation, 3. Good health
Abstract

Additional Table ST3A-D: Details of the linear regression models used in this study. Model formulae for the various linear regression analyses showing how the different co-variates were used.

15. Additional file 2: of Evaluation of the performances of six commercial kits designed for dengue NS1 and anti-dengue IgM, IgG and IgA detection in urine and saliva clinical specimens

Author

Anne-Claire Andries, Veasna Duong, Sivuth Ong, Sopheaktra Ros, Anavaj Sakuntabhai, Horwood, Paul, Dussart, Philippe, and Buchy, Philippe

Subjects
viruses, parasitic diseases, virus diseases, cardiovascular diseases, biochemical phenomena, metabolism, and nutrition, 3. Good health
Abstract

Concordance between RDTs and IPC ELISAs for NS1, anti-DENV IgG/IgM and anti-DENV IgA detection in saliva and urine. (PDF 29 kb)

16. Additional file 6: of Genetic determinants of anti-malarial acquired immunity in a large multi-centre study

Author

Shelton, Jennifer, Corran, Patrick, Risley, Paul, Nilupa Silva, Hubbart, Christina, Jeffreys, Anna, Rowlands, Kate, Craik, Rachel, Cornelius, Victoria, Hensmann, Meike, Molloy, Sile, Sepulveda, Nuno, Taane Clark, Band, Gavin, Clarke, Geraldine, Spencer, Christopher, Kerasidou, Angeliki, Campino, Susana, Auburn, Sarah, Tall, Adama, Alioune Ly, Mercereau-Puijalon, Odile, Anavaj Sakuntabhai, Abdoulaye DjimdĂŠ, Boubacar Maiga, Ousmane TourĂŠ, Ogobara Doumbo, Amagana Dolo, Troye-Blomberg, Marita, Mangano, Valentina, Verra, Frederica, Modiano, David, Bougouma, Edith, Sodiomon Sirima, Muntaser Ibrahim, Hussain, Ayman, Eid, Nahid, Abier Elzein, Mohammed, Hiba, Elhassan, Ahmed, Elhassan, Ibrahim, Williams, Thomas, Ndila, Carolyne, Macharia, Alexander, Marsh, Kevin, Alphaxard Manjurano, Reyburn, Hugh, Lemnge, Martha, Deus Ishengoma, Carter, Richard, Karunaweera, Nadira, Fernando, Deepika, Rajika Dewasurendra, Drakeley, Christopher, Riley, Eleanor, Kwiatkowski, Dominic, and Rockett, Kirk

Subjects
body regions, nervous system, sense organs, equipment and supplies, 3. Good health
Abstract

Additional Figure SF2: Histograms of residuals from antibody linear regression models with non-genetic factors. Histograms of the residuals from the antibody linear regression model analysis with non-genetic factors.

17. Additional file 5: of Genetic determinants of anti-malarial acquired immunity in a large multi-centre study

Author

Shelton, Jennifer, Corran, Patrick, Risley, Paul, Nilupa Silva, Hubbart, Christina, Jeffreys, Anna, Rowlands, Kate, Craik, Rachel, Cornelius, Victoria, Hensmann, Meike, Molloy, Sile, Sepulveda, Nuno, Taane Clark, Band, Gavin, Clarke, Geraldine, Spencer, Christopher, Kerasidou, Angeliki, Campino, Susana, Auburn, Sarah, Tall, Adama, Alioune Ly, Mercereau-Puijalon, Odile, Anavaj Sakuntabhai, Abdoulaye DjimdĂŠ, Boubacar Maiga, Ousmane TourĂŠ, Ogobara Doumbo, Amagana Dolo, Troye-Blomberg, Marita, Mangano, Valentina, Verra, Frederica, Modiano, David, Bougouma, Edith, Sodiomon Sirima, Muntaser Ibrahim, Hussain, Ayman, Eid, Nahid, Abier Elzein, Mohammed, Hiba, Elhassan, Ahmed, Elhassan, Ibrahim, Williams, Thomas, Ndila, Carolyne, Macharia, Alexander, Marsh, Kevin, Alphaxard Manjurano, Reyburn, Hugh, Lemnge, Martha, Deus Ishengoma, Carter, Richard, Karunaweera, Nadira, Fernando, Deepika, Rajika Dewasurendra, Drakeley, Christopher, Riley, Eleanor, Kwiatkowski, Dominic, and Rockett, Kirk

Subjects
body regions, endocrine system, nervous system, sense organs, equipment and supplies, 3. Good health
Abstract

Additional Figure SF1: Histograms of logged antibody levels before further manipulations were made. Histograms of the logged antibody titres across all samples for each antibody measured in this study.

18. Additional file 15: of Genetic determinants of anti-malarial acquired immunity in a large multi-centre study

Author

Shelton, Jennifer, Corran, Patrick, Risley, Paul, Nilupa Silva, Hubbart, Christina, Jeffreys, Anna, Rowlands, Kate, Craik, Rachel, Cornelius, Victoria, Hensmann, Meike, Molloy, Sile, Sepulveda, Nuno, Taane Clark, Band, Gavin, Clarke, Geraldine, Spencer, Christopher, Kerasidou, Angeliki, Campino, Susana, Auburn, Sarah, Tall, Adama, Alioune Ly, Mercereau-Puijalon, Odile, Anavaj Sakuntabhai, Abdoulaye DjimdĂŠ, Boubacar Maiga, Ousmane TourĂŠ, Ogobara Doumbo, Amagana Dolo, Troye-Blomberg, Marita, Mangano, Valentina, Verra, Frederica, Modiano, David, Bougouma, Edith, Sodiomon Sirima, Muntaser Ibrahim, Hussain, Ayman, Eid, Nahid, Abier Elzein, Mohammed, Hiba, Elhassan, Ahmed, Elhassan, Ibrahim, Williams, Thomas, Ndila, Carolyne, Macharia, Alexander, Marsh, Kevin, Alphaxard Manjurano, Reyburn, Hugh, Lemnge, Martha, Deus Ishengoma, Carter, Richard, Karunaweera, Nadira, Fernando, Deepika, Rajika Dewasurendra, Drakeley, Christopher, Riley, Eleanor, Kwiatkowski, Dominic, and Rockett, Kirk

Subjects
3. Good health
Abstract

Additional Table ST9: Details of 196 genotyped SNPs and their derived allele frequencies at each site. This table shows allele frequencies for each SNP analysed in this study according to each study site.

19. Additional file 13: of Genetic determinants of anti-malarial acquired immunity in a large multi-centre study

Author

Shelton, Jennifer, Corran, Patrick, Risley, Paul, Nilupa Silva, Hubbart, Christina, Jeffreys, Anna, Rowlands, Kate, Craik, Rachel, Cornelius, Victoria, Hensmann, Meike, Molloy, Sile, Sepulveda, Nuno, Taane Clark, Band, Gavin, Clarke, Geraldine, Spencer, Christopher, Kerasidou, Angeliki, Campino, Susana, Auburn, Sarah, Tall, Adama, Alioune Ly, Mercereau-Puijalon, Odile, Anavaj Sakuntabhai, Abdoulaye DjimdĂŠ, Boubacar Maiga, Ousmane TourĂŠ, Ogobara Doumbo, Amagana Dolo, Troye-Blomberg, Marita, Mangano, Valentina, Verra, Frederica, Modiano, David, Bougouma, Edith, Sodiomon Sirima, Muntaser Ibrahim, Hussain, Ayman, Eid, Nahid, Abier Elzein, Mohammed, Hiba, Elhassan, Ahmed, Elhassan, Ibrahim, Williams, Thomas, Ndila, Carolyne, Macharia, Alexander, Marsh, Kevin, Alphaxard Manjurano, Reyburn, Hugh, Lemnge, Martha, Deus Ishengoma, Carter, Richard, Karunaweera, Nadira, Fernando, Deepika, Rajika Dewasurendra, Drakeley, Christopher, Riley, Eleanor, Kwiatkowski, Dominic, and Rockett, Kirk

Subjects
3. Good health
Abstract

Additional Table ST7Aâ E: Results of site-specific linear regression analysis investigating the effect of age, gender and malaria status as determined by microscopy on antibody levels to the different antibodies measured in the study. This data shows the site-specific analyses of the various epidemiological parameters and antibody measurements.

20. Additional file 2: of Genetic determinants of anti-malarial acquired immunity in a large multi-centre study

Author

Shelton, Jennifer, Corran, Patrick, Risley, Paul, Nilupa Silva, Hubbart, Christina, Jeffreys, Anna, Rowlands, Kate, Craik, Rachel, Cornelius, Victoria, Hensmann, Meike, Molloy, Sile, Sepulveda, Nuno, Taane Clark, Band, Gavin, Clarke, Geraldine, Spencer, Christopher, Kerasidou, Angeliki, Campino, Susana, Auburn, Sarah, Tall, Adama, Alioune Ly, Mercereau-Puijalon, Odile, Anavaj Sakuntabhai, Abdoulaye DjimdĂŠ, Boubacar Maiga, Ousmane TourĂŠ, Ogobara Doumbo, Amagana Dolo, Troye-Blomberg, Marita, Mangano, Valentina, Verra, Frederica, Modiano, David, Bougouma, Edith, Sodiomon Sirima, Muntaser Ibrahim, Hussain, Ayman, Eid, Nahid, Abier Elzein, Mohammed, Hiba, Elhassan, Ahmed, Elhassan, Ibrahim, Williams, Thomas, Ndila, Carolyne, Macharia, Alexander, Marsh, Kevin, Alphaxard Manjurano, Reyburn, Hugh, Lemnge, Martha, Deus Ishengoma, Carter, Richard, Karunaweera, Nadira, Fernando, Deepika, Rajika Dewasurendra, Drakeley, Christopher, Riley, Eleanor, Kwiatkowski, Dominic, and Rockett, Kirk

Subjects
3. Good health
Abstract

Additional Table ST2: Details of covariates adjusted for in linear regression analysis of non-genetic factors with logged antibody levels, their relevance to the study and their previous association(s) with malaria or anti-malarial antibodies. Information on the covariates used in this study as con-variates in the various analyses.

21. Additional file 16: of Genetic determinants of anti-malarial acquired immunity in a large multi-centre study

Author

Shelton, Jennifer, Corran, Patrick, Risley, Paul, Nilupa Silva, Hubbart, Christina, Jeffreys, Anna, Rowlands, Kate, Craik, Rachel, Cornelius, Victoria, Hensmann, Meike, Molloy, Sile, Sepulveda, Nuno, Taane Clark, Band, Gavin, Clarke, Geraldine, Spencer, Christopher, Kerasidou, Angeliki, Campino, Susana, Auburn, Sarah, Tall, Adama, Alioune Ly, Mercereau-Puijalon, Odile, Anavaj Sakuntabhai, Abdoulaye DjimdĂŠ, Boubacar Maiga, Ousmane TourĂŠ, Ogobara Doumbo, Amagana Dolo, Troye-Blomberg, Marita, Mangano, Valentina, Verra, Frederica, Modiano, David, Bougouma, Edith, Sodiomon Sirima, Muntaser Ibrahim, Hussain, Ayman, Eid, Nahid, Abier Elzein, Mohammed, Hiba, Elhassan, Ahmed, Elhassan, Ibrahim, Williams, Thomas, Ndila, Carolyne, Macharia, Alexander, Marsh, Kevin, Alphaxard Manjurano, Reyburn, Hugh, Lemnge, Martha, Deus Ishengoma, Carter, Richard, Karunaweera, Nadira, Fernando, Deepika, Rajika Dewasurendra, Drakeley, Christopher, Riley, Eleanor, Kwiatkowski, Dominic, and Rockett, Kirk

Subjects
3. Good health
Abstract

Additional Table ST10: Meta-analysis p-values obtained for 178 SNPs passing QC criteria detailed in materials and methods. Details of the analyses for each SNP and antibody across all sites for different genetic inheritance models.

22. Additional file 11: of Genetic determinants of anti-malarial acquired immunity in a large multi-centre study

Author

Shelton, Jennifer, Corran, Patrick, Risley, Paul, Nilupa Silva, Hubbart, Christina, Jeffreys, Anna, Rowlands, Kate, Craik, Rachel, Cornelius, Victoria, Hensmann, Meike, Molloy, Sile, Sepulveda, Nuno, Taane Clark, Band, Gavin, Clarke, Geraldine, Spencer, Christopher, Kerasidou, Angeliki, Campino, Susana, Auburn, Sarah, Tall, Adama, Alioune Ly, Mercereau-Puijalon, Odile, Anavaj Sakuntabhai, Abdoulaye DjimdĂŠ, Boubacar Maiga, Ousmane TourĂŠ, Ogobara Doumbo, Amagana Dolo, Troye-Blomberg, Marita, Mangano, Valentina, Verra, Frederica, Modiano, David, Bougouma, Edith, Sodiomon Sirima, Muntaser Ibrahim, Hussain, Ayman, Eid, Nahid, Abier Elzein, Mohammed, Hiba, Elhassan, Ahmed, Elhassan, Ibrahim, Williams, Thomas, Ndila, Carolyne, Macharia, Alexander, Marsh, Kevin, Alphaxard Manjurano, Reyburn, Hugh, Lemnge, Martha, Deus Ishengoma, Carter, Richard, Karunaweera, Nadira, Fernando, Deepika, Rajika Dewasurendra, Drakeley, Christopher, Riley, Eleanor, Kwiatkowski, Dominic, and Rockett, Kirk

Subjects
parasitic diseases, 3. Good health
Abstract

Additional table ST5: Linear regression analysis of the correlations between residuals from the malaria antibody pairs. This data shows the results of the analysis of the correlations between antibodies.

23. Additional file 8: of Genetic determinants of anti-malarial acquired immunity in a large multi-centre study

Author

Shelton, Jennifer, Corran, Patrick, Risley, Paul, Nilupa Silva, Hubbart, Christina, Jeffreys, Anna, Rowlands, Kate, Craik, Rachel, Cornelius, Victoria, Hensmann, Meike, Molloy, Sile, Sepulveda, Nuno, Taane Clark, Band, Gavin, Clarke, Geraldine, Spencer, Christopher, Kerasidou, Angeliki, Campino, Susana, Auburn, Sarah, Tall, Adama, Alioune Ly, Mercereau-Puijalon, Odile, Anavaj Sakuntabhai, Abdoulaye DjimdĂŠ, Boubacar Maiga, Ousmane TourĂŠ, Ogobara Doumbo, Amagana Dolo, Troye-Blomberg, Marita, Mangano, Valentina, Verra, Frederica, Modiano, David, Bougouma, Edith, Sodiomon Sirima, Muntaser Ibrahim, Hussain, Ayman, Eid, Nahid, Abier Elzein, Mohammed, Hiba, Elhassan, Ahmed, Elhassan, Ibrahim, Williams, Thomas, Ndila, Carolyne, Macharia, Alexander, Marsh, Kevin, Alphaxard Manjurano, Reyburn, Hugh, Lemnge, Martha, Deus Ishengoma, Carter, Richard, Karunaweera, Nadira, Fernando, Deepika, Rajika Dewasurendra, Drakeley, Christopher, Riley, Eleanor, Kwiatkowski, Dominic, and Rockett, Kirk

Subjects
parasitic diseases, 3. Good health
Abstract

Additional Table ST4: Results of linear regression analysis investigating the effect of age, gender and HbS genotype on parasite density in malaria-positive individuals using combined site data. Results of linear regression analysis investigating the effect of age, gender and HbS genotype on parasite density in malaria-positive individuals using combined data. This is an extension to that shown in the main text and is a reduced dataset as not all sites provided parasitaemia data.

24. Additional file 15: of Genetic determinants of anti-malarial acquired immunity in a large multi-centre study

Author

Shelton, Jennifer, Corran, Patrick, Risley, Paul, Nilupa Silva, Hubbart, Christina, Jeffreys, Anna, Rowlands, Kate, Craik, Rachel, Cornelius, Victoria, Hensmann, Meike, Molloy, Sile, Sepulveda, Nuno, Taane Clark, Band, Gavin, Clarke, Geraldine, Spencer, Christopher, Kerasidou, Angeliki, Campino, Susana, Auburn, Sarah, Tall, Adama, Alioune Ly, Mercereau-Puijalon, Odile, Anavaj Sakuntabhai, Abdoulaye DjimdĂŠ, Boubacar Maiga, Ousmane TourĂŠ, Ogobara Doumbo, Amagana Dolo, Troye-Blomberg, Marita, Mangano, Valentina, Verra, Frederica, Modiano, David, Bougouma, Edith, Sodiomon Sirima, Muntaser Ibrahim, Hussain, Ayman, Eid, Nahid, Abier Elzein, Mohammed, Hiba, Elhassan, Ahmed, Elhassan, Ibrahim, Williams, Thomas, Ndila, Carolyne, Macharia, Alexander, Marsh, Kevin, Alphaxard Manjurano, Reyburn, Hugh, Lemnge, Martha, Deus Ishengoma, Carter, Richard, Karunaweera, Nadira, Fernando, Deepika, Rajika Dewasurendra, Drakeley, Christopher, Riley, Eleanor, Kwiatkowski, Dominic, and Rockett, Kirk

Subjects
3. Good health
Abstract

Additional Table ST9: Details of 196 genotyped SNPs and their derived allele frequencies at each site. This table shows allele frequencies for each SNP analysed in this study according to each study site.

25. Additional file 1: of Inhibition of protein kinase C promotes dengue virus replication

Author

Warobon Noppakunmongkolchai, Teera Poyomtip, Thichakorn Jittawuttipoka, Natthanej Luplertlop, Anavaj Sakuntabhai, Sarin Chimnaronk, Siwanon Jirawatnotai, and Rutaiwan Tohtong

Subjects
nervous system, viruses, fungi, virus diseases, biochemical phenomena, metabolism, and nutrition, 3. Good health
Abstract

Viral kinetics of wild type DENV 16681, and the recombinant DENV etDENV. (PDF 63 kb)

26. Additional file 6: of Genetic determinants of anti-malarial acquired immunity in a large multi-centre study

Author

Shelton, Jennifer, Corran, Patrick, Risley, Paul, Nilupa Silva, Hubbart, Christina, Jeffreys, Anna, Rowlands, Kate, Craik, Rachel, Cornelius, Victoria, Hensmann, Meike, Molloy, Sile, Sepulveda, Nuno, Taane Clark, Band, Gavin, Clarke, Geraldine, Spencer, Christopher, Kerasidou, Angeliki, Campino, Susana, Auburn, Sarah, Tall, Adama, Alioune Ly, Mercereau-Puijalon, Odile, Anavaj Sakuntabhai, Abdoulaye DjimdĂŠ, Boubacar Maiga, Ousmane TourĂŠ, Ogobara Doumbo, Amagana Dolo, Troye-Blomberg, Marita, Mangano, Valentina, Verra, Frederica, Modiano, David, Bougouma, Edith, Sodiomon Sirima, Muntaser Ibrahim, Hussain, Ayman, Eid, Nahid, Abier Elzein, Mohammed, Hiba, Elhassan, Ahmed, Elhassan, Ibrahim, Williams, Thomas, Ndila, Carolyne, Macharia, Alexander, Marsh, Kevin, Alphaxard Manjurano, Reyburn, Hugh, Lemnge, Martha, Deus Ishengoma, Carter, Richard, Karunaweera, Nadira, Fernando, Deepika, Rajika Dewasurendra, Drakeley, Christopher, Riley, Eleanor, Kwiatkowski, Dominic, and Rockett, Kirk

Subjects
body regions, nervous system, sense organs, equipment and supplies, 3. Good health
Abstract

Additional Figure SF2: Histograms of residuals from antibody linear regression models with non-genetic factors. Histograms of the residuals from the antibody linear regression model analysis with non-genetic factors.

27. Additional file 7: of Genetic determinants of anti-malarial acquired immunity in a large multi-centre study

Author

Shelton, Jennifer, Corran, Patrick, Risley, Paul, Nilupa Silva, Hubbart, Christina, Jeffreys, Anna, Rowlands, Kate, Craik, Rachel, Cornelius, Victoria, Hensmann, Meike, Molloy, Sile, Sepulveda, Nuno, Taane Clark, Band, Gavin, Clarke, Geraldine, Spencer, Christopher, Kerasidou, Angeliki, Campino, Susana, Auburn, Sarah, Tall, Adama, Alioune Ly, Mercereau-Puijalon, Odile, Anavaj Sakuntabhai, Abdoulaye DjimdĂŠ, Boubacar Maiga, Ousmane TourĂŠ, Ogobara Doumbo, Amagana Dolo, Troye-Blomberg, Marita, Mangano, Valentina, Verra, Frederica, Modiano, David, Bougouma, Edith, Sodiomon Sirima, Muntaser Ibrahim, Hussain, Ayman, Eid, Nahid, Abier Elzein, Mohammed, Hiba, Elhassan, Ahmed, Elhassan, Ibrahim, Williams, Thomas, Ndila, Carolyne, Macharia, Alexander, Marsh, Kevin, Alphaxard Manjurano, Reyburn, Hugh, Lemnge, Martha, Deus Ishengoma, Carter, Richard, Karunaweera, Nadira, Fernando, Deepika, Rajika Dewasurendra, Drakeley, Christopher, Riley, Eleanor, Kwiatkowski, Dominic, and Rockett, Kirk

Subjects
Statistics::Machine Learning, Statistics::Theory, Statistics::Methodology, Statistics::Computation, 3. Good health
Abstract

Additional Table ST3A-D: Details of the linear regression models used in this study. Model formulae for the various linear regression analyses showing how the different co-variates were used.

28. Additional file 4: of Genetic determinants of anti-malarial acquired immunity in a large multi-centre study

Author

Shelton, Jennifer, Corran, Patrick, Risley, Paul, Nilupa Silva, Hubbart, Christina, Jeffreys, Anna, Rowlands, Kate, Craik, Rachel, Cornelius, Victoria, Hensmann, Meike, Molloy, Sile, Sepulveda, Nuno, Taane Clark, Band, Gavin, Clarke, Geraldine, Spencer, Christopher, Kerasidou, Angeliki, Campino, Susana, Auburn, Sarah, Tall, Adama, Alioune Ly, Mercereau-Puijalon, Odile, Anavaj Sakuntabhai, Abdoulaye DjimdĂŠ, Boubacar Maiga, Ousmane TourĂŠ, Ogobara Doumbo, Amagana Dolo, Troye-Blomberg, Marita, Mangano, Valentina, Verra, Frederica, Modiano, David, Bougouma, Edith, Sodiomon Sirima, Muntaser Ibrahim, Hussain, Ayman, Eid, Nahid, Abier Elzein, Mohammed, Hiba, Elhassan, Ahmed, Elhassan, Ibrahim, Williams, Thomas, Ndila, Carolyne, Macharia, Alexander, Marsh, Kevin, Alphaxard Manjurano, Reyburn, Hugh, Lemnge, Martha, Deus Ishengoma, Carter, Richard, Karunaweera, Nadira, Fernando, Deepika, Rajika Dewasurendra, Drakeley, Christopher, Riley, Eleanor, Kwiatkowski, Dominic, and Rockett, Kirk

Subjects
3. Good health
Abstract

MalariaGEN Supplementary Sample Handling Procedures. This file includes more detail on sample handling procedures including extracting DNA, genotyping methodology, ELISA protocols with ELISA data processing.

29. Additional file 18: of Genetic determinants of anti-malarial acquired immunity in a large multi-centre study

Author

Shelton, Jennifer, Corran, Patrick, Risley, Paul, Nilupa Silva, Hubbart, Christina, Jeffreys, Anna, Rowlands, Kate, Craik, Rachel, Cornelius, Victoria, Hensmann, Meike, Molloy, Sile, Sepulveda, Nuno, Taane Clark, Band, Gavin, Clarke, Geraldine, Spencer, Christopher, Kerasidou, Angeliki, Campino, Susana, Auburn, Sarah, Tall, Adama, Alioune Ly, Mercereau-Puijalon, Odile, Anavaj Sakuntabhai, Abdoulaye DjimdĂŠ, Boubacar Maiga, Ousmane TourĂŠ, Ogobara Doumbo, Amagana Dolo, Troye-Blomberg, Marita, Mangano, Valentina, Verra, Frederica, Modiano, David, Bougouma, Edith, Sodiomon Sirima, Muntaser Ibrahim, Hussain, Ayman, Eid, Nahid, Abier Elzein, Mohammed, Hiba, Elhassan, Ahmed, Elhassan, Ibrahim, Williams, Thomas, Ndila, Carolyne, Macharia, Alexander, Marsh, Kevin, Alphaxard Manjurano, Reyburn, Hugh, Lemnge, Martha, Deus Ishengoma, Carter, Richard, Karunaweera, Nadira, Fernando, Deepika, Rajika Dewasurendra, Drakeley, Christopher, Riley, Eleanor, Kwiatkowski, Dominic, and Rockett, Kirk

Subjects
parasitic diseases, 3. Good health
Abstract

Additional Figure SF6: Forest plot of the association of A: CD36 (rs3211938), B: LOC441108 (rs2522051), C: RTN3 (rs542998) and D: P4HA2 (rs156029) with antibody levels to AMA1, MSP1, MSP2 and NANP. Forest plots of the betas obtained from meta-analysis of results obtained from linear regression models of SNP with logged antibody levels, adjusted for relevant clinical covariates.

30. Additional file 11: of Genetic determinants of anti-malarial acquired immunity in a large multi-centre study

Author

Shelton, Jennifer, Corran, Patrick, Risley, Paul, Nilupa Silva, Hubbart, Christina, Jeffreys, Anna, Rowlands, Kate, Craik, Rachel, Cornelius, Victoria, Hensmann, Meike, Molloy, Sile, Sepulveda, Nuno, Taane Clark, Band, Gavin, Clarke, Geraldine, Spencer, Christopher, Kerasidou, Angeliki, Campino, Susana, Auburn, Sarah, Tall, Adama, Alioune Ly, Mercereau-Puijalon, Odile, Anavaj Sakuntabhai, Abdoulaye DjimdĂŠ, Boubacar Maiga, Ousmane TourĂŠ, Ogobara Doumbo, Amagana Dolo, Troye-Blomberg, Marita, Mangano, Valentina, Verra, Frederica, Modiano, David, Bougouma, Edith, Sodiomon Sirima, Muntaser Ibrahim, Hussain, Ayman, Eid, Nahid, Abier Elzein, Mohammed, Hiba, Elhassan, Ahmed, Elhassan, Ibrahim, Williams, Thomas, Ndila, Carolyne, Macharia, Alexander, Marsh, Kevin, Alphaxard Manjurano, Reyburn, Hugh, Lemnge, Martha, Deus Ishengoma, Carter, Richard, Karunaweera, Nadira, Fernando, Deepika, Rajika Dewasurendra, Drakeley, Christopher, Riley, Eleanor, Kwiatkowski, Dominic, and Rockett, Kirk

Subjects
parasitic diseases, 3. Good health
Abstract

Additional table ST5: Linear regression analysis of the correlations between residuals from the malaria antibody pairs. This data shows the results of the analysis of the correlations between antibodies.

31. Additional file 1: of Genetic determinants of anti-malarial acquired immunity in a large multi-centre study

Author

Shelton, Jennifer, Corran, Patrick, Risley, Paul, Nilupa Silva, Hubbart, Christina, Jeffreys, Anna, Rowlands, Kate, Craik, Rachel, Cornelius, Victoria, Hensmann, Meike, Molloy, Sile, Sepulveda, Nuno, Taane Clark, Band, Gavin, Clarke, Geraldine, Spencer, Christopher, Kerasidou, Angeliki, Campino, Susana, Auburn, Sarah, Tall, Adama, Alioune Ly, Mercereau-Puijalon, Odile, Anavaj Sakuntabhai, Abdoulaye DjimdĂŠ, Boubacar Maiga, Ousmane TourĂŠ, Ogobara Doumbo, Amagana Dolo, Troye-Blomberg, Marita, Mangano, Valentina, Verra, Frederica, Modiano, David, Bougouma, Edith, Sodiomon Sirima, Muntaser Ibrahim, Hussain, Ayman, Eid, Nahid, Abier Elzein, Mohammed, Hiba, Elhassan, Ahmed, Elhassan, Ibrahim, Williams, Thomas, Ndila, Carolyne, Macharia, Alexander, Marsh, Kevin, Alphaxard Manjurano, Reyburn, Hugh, Lemnge, Martha, Deus Ishengoma, Carter, Richard, Karunaweera, Nadira, Fernando, Deepika, Rajika Dewasurendra, Drakeley, Christopher, Riley, Eleanor, Kwiatkowski, Dominic, and Rockett, Kirk

Subjects
education, 3. Good health
Abstract

Additional Table ST1 Details of Principal Investigators and Ethics Review Committees for each site. Details of Principal Investigators and Ethics Review Committees for each site.

32. Additional file 1: of Inhibition of protein kinase C promotes dengue virus replication

Author

Warobon Noppakunmongkolchai, Teera Poyomtip, Thichakorn Jittawuttipoka, Natthanej Luplertlop, Anavaj Sakuntabhai, Sarin Chimnaronk, Siwanon Jirawatnotai, and Rutaiwan Tohtong

Subjects
nervous system, viruses, fungi, virus diseases, biochemical phenomena, metabolism, and nutrition, 3. Good health
Abstract

Viral kinetics of wild type DENV 16681, and the recombinant DENV etDENV. (PDF 63 kb)

33. Additional file 13: of Genetic determinants of anti-malarial acquired immunity in a large multi-centre study

Author

Shelton, Jennifer, Corran, Patrick, Risley, Paul, Nilupa Silva, Hubbart, Christina, Jeffreys, Anna, Rowlands, Kate, Craik, Rachel, Cornelius, Victoria, Hensmann, Meike, Molloy, Sile, Sepulveda, Nuno, Taane Clark, Band, Gavin, Clarke, Geraldine, Spencer, Christopher, Kerasidou, Angeliki, Campino, Susana, Auburn, Sarah, Tall, Adama, Alioune Ly, Mercereau-Puijalon, Odile, Anavaj Sakuntabhai, Abdoulaye DjimdĂŠ, Boubacar Maiga, Ousmane TourĂŠ, Ogobara Doumbo, Amagana Dolo, Troye-Blomberg, Marita, Mangano, Valentina, Verra, Frederica, Modiano, David, Bougouma, Edith, Sodiomon Sirima, Muntaser Ibrahim, Hussain, Ayman, Eid, Nahid, Abier Elzein, Mohammed, Hiba, Elhassan, Ahmed, Elhassan, Ibrahim, Williams, Thomas, Ndila, Carolyne, Macharia, Alexander, Marsh, Kevin, Alphaxard Manjurano, Reyburn, Hugh, Lemnge, Martha, Deus Ishengoma, Carter, Richard, Karunaweera, Nadira, Fernando, Deepika, Rajika Dewasurendra, Drakeley, Christopher, Riley, Eleanor, Kwiatkowski, Dominic, and Rockett, Kirk

Subjects
3. Good health
Abstract

Additional Table ST7Aâ E: Results of site-specific linear regression analysis investigating the effect of age, gender and malaria status as determined by microscopy on antibody levels to the different antibodies measured in the study. This data shows the site-specific analyses of the various epidemiological parameters and antibody measurements.

34. Additional file 9: of Genetic determinants of anti-malarial acquired immunity in a large multi-centre study

Author

Shelton, Jennifer, Corran, Patrick, Risley, Paul, Nilupa Silva, Hubbart, Christina, Jeffreys, Anna, Rowlands, Kate, Craik, Rachel, Cornelius, Victoria, Hensmann, Meike, Molloy, Sile, Sepulveda, Nuno, Taane Clark, Band, Gavin, Clarke, Geraldine, Spencer, Christopher, Kerasidou, Angeliki, Campino, Susana, Auburn, Sarah, Tall, Adama, Alioune Ly, Mercereau-Puijalon, Odile, Anavaj Sakuntabhai, Abdoulaye DjimdĂŠ, Boubacar Maiga, Ousmane TourĂŠ, Ogobara Doumbo, Amagana Dolo, Troye-Blomberg, Marita, Mangano, Valentina, Verra, Frederica, Modiano, David, Bougouma, Edith, Sodiomon Sirima, Muntaser Ibrahim, Hussain, Ayman, Eid, Nahid, Abier Elzein, Mohammed, Hiba, Elhassan, Ahmed, Elhassan, Ibrahim, Williams, Thomas, Ndila, Carolyne, Macharia, Alexander, Marsh, Kevin, Alphaxard Manjurano, Reyburn, Hugh, Lemnge, Martha, Deus Ishengoma, Carter, Richard, Karunaweera, Nadira, Fernando, Deepika, Rajika Dewasurendra, Drakeley, Christopher, Riley, Eleanor, Kwiatkowski, Dominic, and Rockett, Kirk

Subjects
3. Good health
Abstract

Additional figure SF3: Heatmap matrix plot of the correlations between residuals from the antibody linear regression models with non-genetic factors at each site. Matrix plot of the pairwise correlations as r2 between antibody titres using data from all sites.

35. Additional file 1: of Evaluation of the performances of six commercial kits designed for dengue NS1 and anti-dengue IgM, IgG and IgA detection in urine and saliva clinical specimens

Author

Anne-Claire Andries, Veasna Duong, Sivuth Ong, Sopheaktra Ros, Anavaj Sakuntabhai, Horwood, Paul, Dussart, Philippe, and Buchy, Philippe

Subjects
viruses, virus diseases, biochemical phenomena, metabolism, and nutrition, 3. Good health
Abstract

Characteristics of the rapid diagnostic tests for NS1, anti-DENV IgG/IgM and anti-DENV IgA detection in saliva and urine according to the manufacturerâ s instructions. (PDF 87 kb)

36. Additional file 14: of Genetic determinants of anti-malarial acquired immunity in a large multi-centre study

Author

Shelton, Jennifer, Corran, Patrick, Risley, Paul, Nilupa Silva, Hubbart, Christina, Jeffreys, Anna, Rowlands, Kate, Craik, Rachel, Cornelius, Victoria, Hensmann, Meike, Molloy, Sile, Sepulveda, Nuno, Taane Clark, Band, Gavin, Clarke, Geraldine, Spencer, Christopher, Kerasidou, Angeliki, Campino, Susana, Auburn, Sarah, Tall, Adama, Alioune Ly, Mercereau-Puijalon, Odile, Anavaj Sakuntabhai, Abdoulaye DjimdĂŠ, Boubacar Maiga, Ousmane TourĂŠ, Ogobara Doumbo, Amagana Dolo, Troye-Blomberg, Marita, Mangano, Valentina, Verra, Frederica, Modiano, David, Bougouma, Edith, Sodiomon Sirima, Muntaser Ibrahim, Hussain, Ayman, Eid, Nahid, Abier Elzein, Mohammed, Hiba, Elhassan, Ahmed, Elhassan, Ibrahim, Williams, Thomas, Ndila, Carolyne, Macharia, Alexander, Marsh, Kevin, Alphaxard Manjurano, Reyburn, Hugh, Lemnge, Martha, Deus Ishengoma, Carter, Richard, Karunaweera, Nadira, Fernando, Deepika, Rajika Dewasurendra, Drakeley, Christopher, Riley, Eleanor, Kwiatkowski, Dominic, and Rockett, Kirk

Subjects
parasitic diseases, 3. Good health
Abstract

Additional Table ST8: Results of linear regression analysis investigating the effect of age, gender, malaria status as determined by microscopy and bednet use* on logged antibody levels to AMA1, MSP1, MSP2, NANP and IgE. This table shows the results of the analysis of antibody levels with bednet use. Results shown as betas indicating the direction of effect of the clinical covariates on antibody levels.

37. Additional file 5: of Genetic determinants of anti-malarial acquired immunity in a large multi-centre study

Author

Shelton, Jennifer, Corran, Patrick, Risley, Paul, Nilupa Silva, Hubbart, Christina, Jeffreys, Anna, Rowlands, Kate, Craik, Rachel, Cornelius, Victoria, Hensmann, Meike, Molloy, Sile, Sepulveda, Nuno, Taane Clark, Band, Gavin, Clarke, Geraldine, Spencer, Christopher, Kerasidou, Angeliki, Campino, Susana, Auburn, Sarah, Tall, Adama, Alioune Ly, Mercereau-Puijalon, Odile, Anavaj Sakuntabhai, Abdoulaye DjimdĂŠ, Boubacar Maiga, Ousmane TourĂŠ, Ogobara Doumbo, Amagana Dolo, Troye-Blomberg, Marita, Mangano, Valentina, Verra, Frederica, Modiano, David, Bougouma, Edith, Sodiomon Sirima, Muntaser Ibrahim, Hussain, Ayman, Eid, Nahid, Abier Elzein, Mohammed, Hiba, Elhassan, Ahmed, Elhassan, Ibrahim, Williams, Thomas, Ndila, Carolyne, Macharia, Alexander, Marsh, Kevin, Alphaxard Manjurano, Reyburn, Hugh, Lemnge, Martha, Deus Ishengoma, Carter, Richard, Karunaweera, Nadira, Fernando, Deepika, Rajika Dewasurendra, Drakeley, Christopher, Riley, Eleanor, Kwiatkowski, Dominic, and Rockett, Kirk

Subjects
body regions, endocrine system, nervous system, sense organs, equipment and supplies, 3. Good health
Abstract

Additional Figure SF1: Histograms of logged antibody levels before further manipulations were made. Histograms of the logged antibody titres across all samples for each antibody measured in this study.

38. Additional file 2: of Genetic determinants of anti-malarial acquired immunity in a large multi-centre study

Author

Shelton, Jennifer, Corran, Patrick, Risley, Paul, Nilupa Silva, Hubbart, Christina, Jeffreys, Anna, Rowlands, Kate, Craik, Rachel, Cornelius, Victoria, Hensmann, Meike, Molloy, Sile, Sepulveda, Nuno, Taane Clark, Band, Gavin, Clarke, Geraldine, Spencer, Christopher, Kerasidou, Angeliki, Campino, Susana, Auburn, Sarah, Tall, Adama, Alioune Ly, Mercereau-Puijalon, Odile, Anavaj Sakuntabhai, Abdoulaye DjimdĂŠ, Boubacar Maiga, Ousmane TourĂŠ, Ogobara Doumbo, Amagana Dolo, Troye-Blomberg, Marita, Mangano, Valentina, Verra, Frederica, Modiano, David, Bougouma, Edith, Sodiomon Sirima, Muntaser Ibrahim, Hussain, Ayman, Eid, Nahid, Abier Elzein, Mohammed, Hiba, Elhassan, Ahmed, Elhassan, Ibrahim, Williams, Thomas, Ndila, Carolyne, Macharia, Alexander, Marsh, Kevin, Alphaxard Manjurano, Reyburn, Hugh, Lemnge, Martha, Deus Ishengoma, Carter, Richard, Karunaweera, Nadira, Fernando, Deepika, Rajika Dewasurendra, Drakeley, Christopher, Riley, Eleanor, Kwiatkowski, Dominic, and Rockett, Kirk

Subjects
3. Good health
Abstract

Additional Table ST2: Details of covariates adjusted for in linear regression analysis of non-genetic factors with logged antibody levels, their relevance to the study and their previous association(s) with malaria or anti-malarial antibodies. Information on the covariates used in this study as con-variates in the various analyses.

39. Additional file 1: of Genetic determinants of anti-malarial acquired immunity in a large multi-centre study

Author

Shelton, Jennifer, Corran, Patrick, Risley, Paul, Nilupa Silva, Hubbart, Christina, Jeffreys, Anna, Rowlands, Kate, Craik, Rachel, Cornelius, Victoria, Hensmann, Meike, Molloy, Sile, Sepulveda, Nuno, Taane Clark, Band, Gavin, Clarke, Geraldine, Spencer, Christopher, Kerasidou, Angeliki, Campino, Susana, Auburn, Sarah, Tall, Adama, Alioune Ly, Mercereau-Puijalon, Odile, Anavaj Sakuntabhai, Abdoulaye DjimdĂŠ, Boubacar Maiga, Ousmane TourĂŠ, Ogobara Doumbo, Amagana Dolo, Troye-Blomberg, Marita, Mangano, Valentina, Verra, Frederica, Modiano, David, Bougouma, Edith, Sodiomon Sirima, Muntaser Ibrahim, Hussain, Ayman, Eid, Nahid, Abier Elzein, Mohammed, Hiba, Elhassan, Ahmed, Elhassan, Ibrahim, Williams, Thomas, Ndila, Carolyne, Macharia, Alexander, Marsh, Kevin, Alphaxard Manjurano, Reyburn, Hugh, Lemnge, Martha, Deus Ishengoma, Carter, Richard, Karunaweera, Nadira, Fernando, Deepika, Rajika Dewasurendra, Drakeley, Christopher, Riley, Eleanor, Kwiatkowski, Dominic, and Rockett, Kirk

Subjects
education, 3. Good health
Abstract

Additional Table ST1 Details of Principal Investigators and Ethics Review Committees for each site. Details of Principal Investigators and Ethics Review Committees for each site.

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