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Your search keyword '"Pennington, Taylor"' showing total 5 results
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5 results on '"Pennington, Taylor"'

1. Additional file 1 of TREM2 splice isoforms generate soluble TREM2 species that disrupt long-term potentiation

Author

Moutinho, Miguel, Coronel, Israel, Tsai, Andy P., Di Prisco, Gonzalo Viana, Pennington, Taylor, Atwood, Brady K., Puntambekar, Shweta S., Smith, Daniel C., Martinez, Pablo, Han, Seonggyun, Lee, Younghee, Lasagna-Reeves, Cristian A., Lamb, Bruce T., Bissel, Stephanie J., Nho, Kwangsik, and Landreth, Gary E.

Abstract

Additional file 1: Table S1. Information of post-mortem samples obtained from Johns Hopkins. Table S2. List of primers Table S3. Nucleotide sequence TREM2 HA- and FLAG-tagged constructs Figure S1. Relative expression of TREM2 alternative isoforms, specificity of TREM2 primers and expression of Trem2 splice isoforms amyloidogenic mouse models. Figure S2. Secretion of murine TREM2 isoforms. Figure S3. Soluble TREM2 species inhibit long-term potentiation (LTP) in brain slices of amyloidogenic 5xFAD mice. Figure S4. Murine soluble TREM2 species inhibit LTP. Figure S5. Western blot of TREM2222 and TREM2219, ELISA dilutions and standard curves. Figure S6. Uncropped western blots.

Published
2023
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2. Additional file 9 of Trem2 Y38C mutation and loss of Trem2 impairs neuronal synapses in adult mice

Author

Vaishnavi S. Jadhav, Lin, Peter B. C., Pennington, Taylor, Prisco, Gonzalo Viana Di, Jannu, Asha Jacob, Guixiang Xu, Moutinho, Miguel, Zhang, Jie, Atwood, Brady K., Puntambekar, Shweta S., Bissel, Stephanie J., Oblak, Adrian L., Landreth, Gary E., and Lamb, Bruce T.

Subjects
sense organs
Abstract

Additional file 9 : Table S7. Downregulated genes associated with oligodendrocyte/myelin in Trem2Y38C/Y38C versus WT mice. logFC = Log fold change.

Published
2020
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3. Additional file 2 of Trem2 Y38C mutation and loss of Trem2 impairs neuronal synapses in adult mice

Author

Vaishnavi S. Jadhav, Lin, Peter B. C., Pennington, Taylor, Prisco, Gonzalo Viana Di, Jannu, Asha Jacob, Guixiang Xu, Moutinho, Miguel, Zhang, Jie, Atwood, Brady K., Puntambekar, Shweta S., Bissel, Stephanie J., Oblak, Adrian L., Landreth, Gary E., and Lamb, Bruce T.

Subjects
genetic processes, information science, natural sciences, eye diseases
Abstract

Additional file 2 : Table S2. Primers for Sanger’s sequencing of predicted off-target mutations from CRISPR/Cas9.

Published
2020
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4. Additional file 10 of Trem2 Y38C mutation and loss of Trem2 impairs neuronal synapses in adult mice

Author

Vaishnavi S. Jadhav, Lin, Peter B. C., Pennington, Taylor, Prisco, Gonzalo Viana Di, Jannu, Asha Jacob, Guixiang Xu, Moutinho, Miguel, Zhang, Jie, Atwood, Brady K., Puntambekar, Shweta S., Bissel, Stephanie J., Oblak, Adrian L., Landreth, Gary E., and Lamb, Bruce T.

Subjects
sense organs
Abstract

Additional file 10: Table S8. Downregulated genes associated with oligodendrocyte/myelin genes Trem2-/- versus WT mice. logFC = Log fold change.

Published
2020
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5. Additional file 1 of Trem2 Y38C mutation and loss of Trem2 impairs neuronal synapses in adult mice

Author

Vaishnavi S. Jadhav, Lin, Peter B. C., Pennington, Taylor, Prisco, Gonzalo Viana Di, Jannu, Asha Jacob, Guixiang Xu, Moutinho, Miguel, Zhang, Jie, Atwood, Brady K., Puntambekar, Shweta S., Bissel, Stephanie J., Oblak, Adrian L., Landreth, Gary E., and Lamb, Bruce T.

Abstract

Additional file 1: Table S1. Primers for amplification of genomic regions predicted to have off-target mutations from CRISPR/Cas9.

Published
2020
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